Protein Alignment Kif3C and kif13ba

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_005169924.1
• Gene: kif13ba / 571520
• ZFINID: ZDB-GENE-070521-1
• Length: 1822
• Species: Danio rerio
• Alignment Length: 747
• Identity: 222/747 - (29%)
• Similarity: 340/747 - (45%)
• Gaps: 176/747 - (23%)

  Fly     4 NIKVVVRCRPMNQTEKERNCQNIVEI--NE---FAVSVTNPSARISQQKKFIFD-SVYNM-KTDT 61
            |:||.||.||||:.||:.|.:.:||:  |:   ::.::...|:| .|.|.|.:| ..::| :::|
Zfish    10 NVKVAVRVRPMNRREKDLNTKCVVEMEGNQTFLYSTNLGKDSSR-GQPKTFAYDYCFWSMDESET 73

  Fly    62 E------VIYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFE 120
            |      |::..:..||:.:..:|||..||||||||.||::||.|.   .:..|:||:....:||
Zfish    74 EKFAGQDVVFQCLGESLLHNAFQGYNACIFAYGQTGSGKSYTMMGS---VDQPGLIPRLCSSLFE 135

  Fly   121 R--ISMTTNVRYLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNAN 183
            |  :.......:...|:|:|||||::||||:...:...:.  ::|...:|..|..|:...|.:..
Zfish   136 RTVLHQREEESFTVEVSYMEIYNEKVRDLLDPKGSRQALR--VREHKVLGPYVDGLSRLAVESYK 198

  Fly   184 QCYDWLHFGNKNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAGS 248
            .....:..|||:|..|||.||:.|||||.:|.|.|..:  |..:.|...|... .||||||||||
Zfish   199 DIESLMSEGNKSRTVAATNMNEESSRSHAVFNIILTHT--LKDLQSGTSGEKV-SKLSLVDLAGS 260

  Fly   249 ERQRKTGAQGDRLKEASQINLSLSALGNVISSLVD-----GKAKHVPFRDSKLTRLLQDSLGGNT 308
            ||..||||.|:||||.|.||.||:.||.|||:|.|     .|.|.||:|||.||.||:||||||:
Zfish   261 ERAAKTGAAGERLKEGSNINKSLTTLGLVISALADQGAGKNKNKFVPYRDSVLTWLLKDSLGGNS 325

  Fly   309 KTLMISCISPTDIHYDETISTLRYASRAKNISNKPKINEDPKDARLRQYQNEI------------ 361
            :|.|::.:||...:||||:||||||.|||:|.|...:||||....:|:.:.|:
Zfish   326 RTAMVATVSPAADNYDETLSTLRYADRAKSIVNHAVVNEDPNARIIRELREEVEKLRDQLTQAES 390

  Fly   362 ---LYLKRMLQESQQII-----------------------------------------------N 376
               ..||..|:||:::|                                               |
Zfish   391 MKAPELKERLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQSSGIKVGEDKCFLVN 455

  Fly   377 KNNDP--NKIIKSPLKIIQHTNMNS--TKNVQIIDLG---RNCKASFKTNNSILTKP-------- 426
            .|.||  |:::...||  :||.:.|  ::::|:..:|   .:|..:.....::...|
Zfish   456 LNADPALNELLVYYLK--EHTKVGSADSQDIQLCGMGIQAEHCVINITPEGAVFINPYRNSRTCV 518

  Fly   427 NFPLIQSKEEVQLQAR--------SRIDLIKRSLIGGERIHDFELKEKHMARKYAAQRHLSAIAI 483
            |...:.|::::....|        .||:|.||.|.|.|     |..|....:...:...|.....
Zfish   519 NGSPVTSRQQLHHGDRILWGNNHFFRINLPKRRLRGEE-----EEGEGGNMKSSNSNEQLDGEGD 578

  Fly   484 ALSRVKCEDRDLLQGHYATITQEIDIK----NDYIRKCKEKIKMLEMEVSDLNSEFQLDREDYLD 544
            ..|.|..|    :...|.....|:.:|    ||.::...:.::....|  :..:..:..|..|..
Zfish   579 TASEVSSE----VSFSYEFAQTEVMMKALGSNDPMQAVLQSLERQHEE--EKRTALERQRLMYEQ 637

  Fly   545 EIRNLGRQVKFHQQLFLKFSSNPGKFDRNWTPDTILQNSLWNDDLKMWRIPES--------DLIK 601
            |::.|.||:                     |||.           :..:||:|        .:.:
Zfish   638 ELQQLRRQL---------------------TPDR-----------QSMQIPQSQPLQPHYRSMER 670

  Fly   602 LPPATQKSGLHCIHPLVIHSENQHNNQNEIVV 633
            |......|.....|.|     .|.:.:.|:|:
Zfish   671 LSQGGMSSSSSAQHRL-----RQWSEEREVVL 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	152/354 (43%)
kif13ba	XP_005169924.1	KISc_KIF1A_KIF1B	9..363	CDD:276816	154/361 (43%)
		Kinesin_assoc	360..472	CDD:465047	19/113 (17%)
		FHA_KIF13B	450..548	CDD:438782	19/99 (19%)
		KIF1B	774..820	CDD:463574
		DUF3694	1021..>1084	CDD:463599
		bMERB_dom	<1102..1161	CDD:463467
		DUF3694	<1239..1296	CDD:463599
		CAP_GLY	1717..1781	CDD:460154