Protein Alignment Kif3C and KIF15

DIOPT Version :9

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_016862373.1
• Gene: KIF15 / 56992
• HGNCID: 17273
• Length: 1411
• Species: Homo sapiens
• Alignment Length: 587
• Identity: 201/587 - (34%)
• Similarity: 287/587 - (48%)
• Gaps: 105/587 - (17%)

  Fly     5 IKVVVRCRP----MNQTEKERN-CQNIVEINEFAVSVTNPSARISQQKKFIFDSVYNMKTDTEVI 64
            |||.||.||    ....:.|:| |.:::......:. :||     :.|.|.||.|.::.|..|.:
Human    27 IKVFVRIRPPAERSGSADGEQNLCLSVLSSTSLRLH-SNP-----EPKTFTFDHVADVDTTQESV 85

  Fly    65 YDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQG---DENFS-NSTGIIPKCFDHIF-----E 120
            :..:..|:|||.:.|||||||||||||.|||.||.|   .:||| |..|:||:.|:::|     |
Human    86 FATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFSHNLRGVIPRSFEYLFSLIDRE 150

  Fly   121 RISMTTNVRYLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNANQC 185
            :........:|...:::|||||:|.|||:.......:...:|:    ||.|.....|.|.:|.:.
Human   151 KEKAGAGKSFLCKCSFIEIYNEQIYDLLDSASAGLYLREHIKK----GVFVVGAVEQVVTSAAEA 211

  Fly   186 YDWLHFGNKNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAGSER 250
            |..|..|.:||..|:|.||:.|||||.:||||:|.....|.|.:     |....|:|||||||||
Human   212 YQVLSGGWRNRRVASTSMNRESSRSHAVFTITIESMEKSNEIVN-----IRTSLLNLVDLAGSER 271

  Fly   251 QRKTGAQGDRLKEASQINLSLSALGNVISSLVD---GKAKHVPFRDSKLTRLLQDSLGGNTKTLM 312
            |:.|.|:|.|||||..||.|||.||.||::|||   ||.:||.:||||||.||:||||||.||.:
Human   272 QKDTHAEGMRLKEAGNINRSLSCLGQVITALVDVGNGKQRHVCYRDSKLTFLLRDSLGGNAKTAI 336

  Fly   313 ISCISPTDIHYDETISTLRYASRAKNISNKPKINEDPKD---------ARLRQ------------ 356
            |:.:.|....:.||:|||.:|.|||.|.||..:|||.:.         .||::
Human   337 IANVHPGSRCFGETLSTLNFAQRAKLIKNKAVVNEDTQGNVSQLQAEVKRLKEQLAELASGQTPP 401

  Fly   357 ----------------YQNEILYLKRMLQESQQIINKNNDPNKIIKSPLKIIQHTNM-NSTKNVQ 404
                            :|..:|:.|:..||.:.:|.|......:.....|.||...| ...:..|
Human   402 ESFLTRDKKKTNYMEYFQEAMLFFKKSEQEKKSLIEKVTQLEDLTLKKEKFIQSNKMIVKFREDQ 466

  Fly   405 IIDLGRNCKASFKTNNSILTKPNFPLIQSKEEVQLQARSRIDLIKRSLIGGERIHDFELKEKH-M 468
            ||.|.:..|.|         :..| |.:.::.:..:.|:.|..::..:            |.| .
Human   467 IIRLEKLHKES---------RGGF-LPEEQDRLLSELRNEIQTLREQI------------EHHPR 509

  Fly   469 ARKYAAQRHLSAIAIALSRVKCEDRDLLQGHYATITQEIDIKNDYIRKCKEKIKMLE-MEVSDLN 532
            ..|||.:.|         .::.|:|.|.........||:|.:.  |.|.::....:. ||.||.|
Human   510 VAKYAMENH---------SLREENRRLRLLEPVKRAQEMDAQT--IAKLEKAFSEISGMEKSDKN 563

  Fly   533 SE 534
            .:
Human   564 QQ 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:277568	153/350 (44%)
		Kinesin	10..339	CDD:278646	149/345 (43%)
KIF15	XP_016862373.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4280
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810