Protein Alignment Kif3C and kif5aa

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001186705.1
• Gene: kif5aa / 566086
• ZFINID: ZDB-GENE-070912-141
• Length: 1033
• Species: Danio rerio
• Alignment Length: 607
• Identity: 191/607 - (31%)
• Similarity: 292/607 - (48%)
• Gaps: 78/607 - (12%)

  Fly     4 NIKVVVRCRPMNQTEKERNCQNIVEINEFAVSVTNPSARISQQKKFIFDSVYNMKTDTEVIYDEM 68
            ||||:.|.||:||.|       |:..::|..:.......|...|.:.||.|:...|..|.:|:..
Zfish     9 NIKVLCRFRPLNQAE-------ILRGDKFLPTFQGDDTVIIGGKSYAFDRVFPTNTTQEQVYNTC 66

  Fly    69 CYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERI-SMTTNVRYLA 132
            ...:|:..:.||||||||||||..||||||:|:.:.....||||:..:.||..| ||..|:.:..
Zfish    67 AKQIVKDVLGGYNGTIFAYGQTSSGKTHTMEGNLHDPQQMGIIPRIAEDIFNHIFSMDENLEFHI 131

  Fly   133 LVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNANQCYDWLHFGNKNRV 197
            .|:|.|||.|:|||||:..:....::.....:|    .|...|.:.|.:..:..|.:..|..||.
Zfish   132 KVSYFEIYMEKIRDLLDVTKTNLSVHEDKNRVP----YVKGCTERFVSSPEEVMDVIDEGKSNRH 192

  Fly   198 TAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAGSERQRKTGAQGDRLK 262
            .|.|.||::|||||:||.|.::|...      :....:| |||.||||||||:..||||.|..|.
Zfish   193 VAVTNMNEHSSRSHSIFLINIKQEHV------ETEQKLC-GKLYLVDLAGSEKVSKTGAAGAVLD 250

  Fly   263 EASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKTLMISCISPTDIHYDETI 327
            ||..||.||||||||||:|.:|...|||:||||:||:||||||||.:|.|..|.||:..:..||.
Zfish   251 EAKNINKSLSALGNVISALAEGTKSHVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETK 315

  Fly   328 STLRYASRAKNISNKPKIN--------------EDPKDARLRQYQNEILYLKRMLQESQQIINKN 378
            |||.:..|||.|.|...||              |..|:..||.....:....|..:..:::....
Zfish   316 STLMFGQRAKTIKNTASINLELTAEQWKRKYEKEKEKNKSLRDSMQRLELELRRWRNGEKVPETE 380

  Fly   379 NDPNKIIKSPLKIIQHTNMNSTKNVQ--------------IIDLGRNCKASFKTNNSILTKPNFP 429
            .....::|  |.:.:.|::::.|:.:              ::.:....:..::..   :.|....
Zfish   381 QTDADVVK--LDVSEETSLDNEKSCERQRERERDSDTSSIVVRISEEERQKYEEE---IRKLYRQ 440

  Fly   430 LIQSKEEVQLQARSRIDLIKRSLIGGERIHDFELKEKHMARKYAAQRHLSAIAIALSRVKCEDRD 494
            |....:|:.||.: .::.:|..::..:     ||...........|..|..:.......|.|.|:
Zfish   441 LDDKDDEINLQCQ-LVEKLKEQILDQD-----ELLASTRGDSDKVQTELGRLQTESESAKAEVRE 499

  Fly   495 LLQG------HYATITQEIDIKNDYIRKCKEKI--KM-----LEMEVSDLNSEFQLDREDYLDEI 546
            :||.      :|...:||::.|:.:.::..|::  ||     ||.|::.:.......|:...|.:
Zfish   500 VLQALEELAVNYDQKSQEVEEKSLHNKQLAEQLSHKMANLMELEAELAQMQEVSSQQRKRIADVL 564

  Fly   547 RNLGRQVKFHQQLFLKFSSNPG 568
            ..|.:.:.       :|||..|
Zfish   565 NGLMKDLS-------EFSSIVG 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	146/335 (44%)
kif5aa	NP_001186705.1	KISc_KHC_KIF5	7..327	CDD:276820	146/335 (44%)
		SMC_prok_B	<334..614	CDD:274008	42/264 (16%)
		SMC_N	478..>809	CDD:481474	24/109 (22%)
		Khc_CBD_cc	842..911	CDD:467880