Protein Alignment Kif3C and kif5ba

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_005171465.1
• Gene: kif5ba / 563459
• ZFINID: ZDB-GENE-070629-2
• Length: 969
• Species: Danio rerio
• Alignment Length: 750
• Identity: 209/750 - (27%)
• Similarity: 340/750 - (45%)
• Gaps: 167/750 - (22%)

  Fly     5 IKVVVRCRPMNQTEKERNCQNIVEINEFAVSVTNPSARISQQKKFIFDSVYNMKTDTEVIYDEMC 69
            |||:.|.||:|.:|..|.       :::..:.....:.:...|.::||.|:...|..|.:|....
Zfish     9 IKVMCRFRPLNSSEVTRG-------DKYIPNFQGQDSVVIGGKPYVFDRVFQSNTTQEQVYTACA 66

  Fly    70 YSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERI-SMTTNVRYLAL 133
            ..:|:..:.||||||||||||..||||||:|:.:.::..||||:....||..| ||..|:.:...
Zfish    67 QQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGNLHDTDGMGIIPRIVQDIFNYIYSMDENLEFHIK 131

  Fly   134 VTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNANQCYDWLHFGNKNRVT 198
            |:|.|||.::|||||:.::....::.....:|    .|...|.:.|.:..:..|.:..|..||..
Zfish   132 VSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVP----YVKGCTERFVCSPEEVMDTIDEGKSNRHV 192

  Fly   199 AATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAGSERQRKTGAQGDRLKE 263
            |.|.||::|||||:||.|.::|.   |:.......    |||.||||||||:..||||:|..|.|
Zfish   193 AVTNMNEHSSRSHSIFLINVKQE---NTQTEQKLS----GKLYLVDLAGSEKVSKTGAEGAVLDE 250

  Fly   264 ASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKTLMISCISPTDIHYDETIS 328
            |..||.|||:||||||:|.:| :.:||:||||:||:||||||||.:|.::.|.||:..:..||.|
Zfish   251 AKNINKSLSSLGNVISALAEG-STYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSAFNEAETKS 314

  Fly   329 TLRYASRAKNISNKPKIN-----------EDPKDARLRQYQNEILYLKRML-------------Q 369
            ||.:..|||.|.|...:|           .:.:..|.:..:|.|.:|:..|             |
Zfish   315 TLMFGQRAKTIKNTVCVNVELTAEQWKKKYEKERERNKSLRNTITWLENELNRWRNGETVPAEEQ 379

  Fly   370 ESQQIINK---------NNDPNKIIKSPL------------------------------------ 389
            ..::.:|.         |||  |...:|.
Zfish   380 YDKEKVNAEVLALDNTINND--KFASTPSMPPMPGMLGTRLTGVEKDKCEVELGKLYKQLDDKDE 442

  Fly   390 KIIQHTNMNSTKNVQIIDLGRNCKASFKTNNSI---LTKPNFPLIQSKEEVQ--LQARSR--IDL 447
            :|.|.:.:......|::|......:|.:.::::   ||:.......|||||:  |||...  ::.
Zfish   443 EINQQSQLVEKLKQQMLDQEELLASSRRDHDNLQAELTRLQLENEASKEEVKEVLQALEELAVNY 507

  Fly   448 IKRSLIGGERIHDFELKEKHMARKYAAQRHLSAIAIALSRVK----------------------- 489
            .::|....::..:||...:.:::|.:.   |::|...|.::|
Zfish   508 DQKSQEVEDKTKEFEALSEELSQKSST---LASIDSELQKLKEMANHQKKRVTEMMSSLLKDLTE 569

  Fly   490 ----CEDRDLLQGHYAT--ITQEIDIKNDYIRKCKEKIKML-----EMEVSDLNSEFQLDREDYL 543
                ..:.|:.| |..:  |.:|..:...||.|.|.::|.:     ::|.:...|..::|..|
Zfish   570 IGIAVGNNDIKQ-HEGSGLIDEEFTVARLYISKMKSEVKSMVKRCKQLENTQSESNKKMDESD-- 631

  Fly   544 DEIRNLGRQVKFHQQLFLKFSSNPGKFDRNWTPDTILQNSLWNDDLKMWRIPE------SDLIKL 602
                   :::...|   |:.|.:..|...       |...|.|.:.|..::.|      .:|:|:
Zfish   632 -------KELAACQ---LRISQHEAKIKS-------LTEYLQNVEQKKRQLEEDVDSLNEELVKI 679

  Fly   603 PPATQKSGLHCIHPLVIHSENQHNNQNEIVVGEKV 637
             .|.:|     :|.:...||.|..|:.:..|.:::
Zfish   680 -SAQEK-----VHAMEKESEIQSANEVKEAVEKQI 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	138/334 (41%)
kif5ba	XP_005171465.1	KISc_KHC_KIF5	6..325	CDD:276820	138/334 (41%)
		SMC_prok_B	<427..806	CDD:274008	56/310 (18%)
		Khc_CBD_cc	837..906	CDD:467880