Protein Alignment Kif3C and kif17

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001373250.1
• Gene: kif17 / 557863
• ZFINID: ZDB-GENE-080724-12
• Length: 823
• Species: Danio rerio
• Alignment Length: 712
• Identity: 271/712 - (38%)
• Similarity: 395/712 - (55%)
• Gaps: 117/712 - (16%)

  Fly     2 SENIKVVVRCRPMNQTEKERNCQNIVEINEFAVS--VTNPSARISQQKKFIFDSVYNMKTDTEVI 64
            ||::||||||||:|..||..||:.:|.::.....  :..|.......|:|.||..|.:...||.:
Zfish     3 SESVKVVVRCRPLNNREKAMNCKIVVSVDSTHCQCFIKKPGDTEEPPKQFTFDGTYYINHSTEEV 67

  Fly    65 YDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERISMTTNVR 129
            |:|:.|.|||...||||||||||||||.||:.||||..:..:..||||:.|:||||.|....|.:
Zfish    68 YNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGVPDPPSQRGIIPRAFEHIFETIQCAENTK 132

  Fly   130 YLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNANQCYDWLHFGNK 194
            :|...:|||||.|.|||||.|:....:   .|||.|..||.|..||.|.|.:..:|...:..|.:
Zfish   133 FLVRASYLEIYKEEIRDLLGKDIKQKM---ELKEHPERGVYVRDLTMQTVHSVGECERVMDLGWR 194

  Fly   195 NRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAGSERQRKTGAQGD 259
            ||....|||||:|||||:||||.||    :.||.:.....:..|||:||||||||||.||||.||
Zfish   195 NRSVGYTLMNKDSSRSHSIFTIHLE----ICSIDTAGDEHLRAGKLNLVDLAGSERQSKTGATGD 255

  Fly   260 RLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKTLMISCISPTDIHYD 324
            ||:||::|||||||||||||:||||::|::|:|||||||||||||||||:|||::|:||.|.:|:
Zfish   256 RLQEATKINLSLSALGNVISALVDGRSKYIPYRDSKLTRLLQDSLGGNTRTLMVACLSPADNNYE 320

  Fly   325 ETISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYLKRMLQ------------------ES 371
            |:|||||||:|||:|.|:|:||||||||.||:||.||..|:.::.                  |:
Zfish   321 ESISTLRYANRAKSIQNRPRINEDPKDALLREYQEEIKKLRALISGQLGSGNLSSFLAGQKSGEA 385

  Fly   372 QQIINK---NNDPNKIIKSPLK---------------IIQHTNMNSTKNVQIIDLGRNCKASFKT 418
            ..::::   |...::..|..:|               ..|.:.:...:::..:      :.|::|
Zfish   386 SAVVSRPQSNTSESEAEKDKIKEEYEKKLARLQAEYDAEQESKVKLQEDIAAL------RTSYET 444

  Fly   419 NNSIL---------TKPNFPLIQSKEE-------VQLQAR------------------------- 442
            ..|.|         |.....|.|.|||       .|.||:
Zfish   445 RLSSLERSRGSRTHTTGGVHLQQHKEEPITASAASQEQAKIDHSESEERPSSVDATVKGAASGES 509

  Fly   443 --------------------SRIDLIKRSLIGGERIHDFELKEKHMARKYAAQRHLSAIAIALSR 487
                                .|:..:::..:|||::.:.|||::|..||..|.:....:..||::
Zfish   510 QILDSVVVDIPGQLDQKLALERLQQLEQEFVGGEQVRNEELKQRHKQRKTLADQRKKQLIEALNQ 574

  Fly   488 VKCEDRD-LLQGHYATITQEIDIKNDYIRKCKEKIKMLEMEVSDLNSEFQLDREDYLDEIRNLGR 551
             ..||.| :|...|.:|.:|:..|:.::...::|:|..::|:.||.:||:::|.|||..||.|.|
Zfish   575 -SSEDGDSVLLNVYDSIQEEVHAKSRHLENTQKKLKAAKLEIRDLQAEFEMERNDYLATIRRLER 638

  Fly   552 QVKFHQQLFLKFSSNPGKFDRNWTP-DTILQNSLWNDDLKMWRIPESDLIKLP-PATQKSGL 611
            :.:..|.:..:..|...: |.|::. |.:.:.::|:::...||:|:..:.|.. ||...||:
Zfish   639 EGQLLQGILERMVSLVRR-DCNYSNLDRLRKEAVWDEEGGTWRLPDVLVQKTTLPAVPPSGV 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	184/337 (55%)
kif17	NP_001373250.1	Motor_domain	4..335	CDD:473979	184/337 (55%)
		Smc	<398..>656	CDD:440809	54/264 (20%)