Protein Alignment Kif3C and kif3cb

DIOPT Version :9

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001017849.2
• Gene: kif3cb / 550547
• ZFINID: ZDB-GENE-080709-4
• Length: 759
• Species: Danio rerio
• Alignment Length: 679
• Identity: 253/679 - (37%)
• Similarity: 375/679 - (55%)
• Gaps: 77/679 - (11%)

  Fly     2 SENIKVVVRCRPMNQTEKERNCQNIVEINE--FAVSVTNPSARISQQKKFIFDSVYNMKTDTEVI 64
            ||.:||||||||:|:.|:..|.:.|||::.  ..|||.||.:..|..|.|.||:||::.:....:
Zfish    19 SEAVKVVVRCRPLNKKEEAMNQERIVEVDVRLGQVSVRNPKSSGSLVKSFTFDAVYDVSSKQNEL 83

  Fly    65 YDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERISMTTNVR 129
            ||..|..|::|.:.|:|||||||||||.|||:||:|......:.|:||..|.|||.:||.:.|.:
Zfish    84 YDYACKPLIDSVLLGFNGTIFAYGQTGTGKTYTMEGVPTDPETRGVIPNSFQHIFTQISRSQNQQ 148

  Fly   130 YLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNANQCYDWLHFGNK 194
            ||..|:|:|||.|.|||||.|:.|..:   .|||.|.:||.|..|:.....|..:....::.||:
Zfish   149 YLVRVSYIEIYQEEIRDLLCKDNNKKL---ELKENPELGVYVKDLSCVVTKNIKEIEHVMNLGNQ 210

  Fly   195 NRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAGSERQRKTGAQGD 259
            :|....|.||:.|||||.||.||:|.|    .:|.|....|..|||::|||||||||.|||.||.
Zfish   211 SRSVGFTKMNERSSRSHAIFVITIECS----EMGIDGEDHIRVGKLNMVDLAGSERQSKTGVQGR 271

  Fly   260 RLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKTLMISCISPTDIHYD 324
            |.|||::|||||||||||||:|||||:.|||:||||||||||||||||.||:|::.:.|...:||
Zfish   272 RFKEAAKINLSLSALGNVISALVDGKSTHVPYRDSKLTRLLQDSLGGNAKTVMVATVGPASCYYD 336

  Fly   325 ETISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYLKRMLQESQQIIN------------K 377
            ||::|||||:|||||.||||||||||||.||::|.||..||..|:|...:..            |
Zfish   337 ETLTTLRYANRAKNIKNKPKINEDPKDALLREFQEEIARLKAQLEERGMLAKERRRQKRNSLRMK 401

  Fly   378 NNDPNKIIKSP----LKIIQHTNMNSTKNV----QIIDLGRNCKASFKTNNSILTKPNFPLIQSK 434
            .:..:..:::|    :::::.....|.::.    |:.....|.|........::.:.    :::.
Zfish   402 RSMSSGEVETPRIGEVEVVETVREESVEDYWWKQQMAKTSANYKPDISRKLGMVNEK----VKTV 462

  Fly   435 EEVQLQARSRIDLIK-------RSLIGGERIHD--------FELKEKHMARKYAAQRHLSAIAIA 484
            ||:..:.::..::|:       :.|:||:.|.|        .||....:|.:...:|.:..:...
Zfish   463 EELLKEQQAMENMIEKYKAMESKLLVGGKNIIDHTNEQQKMLELTRLEIAEQDRKEREMQQLMFE 527

  Fly   485 LSRVKCEDRDLLQGHYATITQEIDIKNDYIRKCKEKIKMLEMEVSDLNSEFQLDREDYLDEIRNL 549
            ......|    |:..::|:.||::.|...:||...|::::..|:.|:.:|....|::....:..|
Zfish   528 QDEETIE----LKETFSTLQQEVEFKTKKLRKFYSKLQLVRSEIGDIINEHVTMRQELEQTMNEL 588

  Fly   550 GRQVKFHQQLFLKFSSNPGKFDRNWTPDTILQNSLWNDDLKMWRIPESDLIKLPPATQKSGLHCI 614
            .|::||...:...|.....|       :.|:....::.:...|::     :.|.|:...|
Zfish   589 TREMKFKNLIIENFIPPEEK-------NKIINRLHFDSEEDQWKV-----LPLLPSENNS----- 636

  Fly   615 HPLVIHSENQHNNQNEIVVGEKVSISNIA 643
             |||       ..:...|||.|..:|..|
Zfish   637 -PLV-------RRRPTSVVGNKRPVSMYA 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:277568	178/337 (53%)
		Kinesin	10..339	CDD:278646	173/330 (52%)
kif3cb	NP_001017849.2	KISc_KIF3	20..351	CDD:276822	178/337 (53%)
		KISc	21..358	CDD:214526	183/343 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4280
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145782at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820