Protein Alignment Kif3C and Kif19A

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_996208.1
• Gene: Kif19A / 41717
• FlyBaseID: FBgn0038205
• Length: 750
• Species: Drosophila melanogaster
• Alignment Length: 684
• Identity: 181/684 - (26%)
• Similarity: 295/684 - (43%)
• Gaps: 153/684 - (22%)

  Fly     3 ENIKVVVRCRP-MNQTEKERNCQNIVEINEFAVSVTNPSARISQQKKFIFDSVYNMKTDTEVIYD 66
            |.:.|.||.|| |..||:   |..::.    ..|:.......|:.:::.:|.|:......|.:|.
  Fly    34 ERLVVAVRVRPSMEATER---CIEVIS----GGSLLYDDGGKSRPRQYSYDHVFRENDSQEQVYK 91

  Fly    67 EMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQG---------------------DENFSNSTGI 110
            .....||...:.|.|..:||||.||.||||||.|                     .:..|...|:
  Fly    92 TTTAPLVRDVLNGLNAAVFAYGATGSGKTHTMLGPVPRKKPQTSDRAPPTASCDSTDVSSQDIGL 156

  Fly   111 IPKCFDHIFERISMTTNVRYLALVTYLEIYNERIRDLLNKNENTNV-INHFLKELPGIGVS-VPT 173
            :.:..:.||..|...........::|||||||.||||||......: .:|..:.:...|:| :.|
  Fly   157 MVRAIEDIFSHIESAEAYSCRVSISYLEIYNELIRDLLNPGGPLELREDHRGQRITVAGLSEITT 221

  Fly   174 LTTQPVVNANQCYDWLHFGNKNRVTAATLMNKNSSRSHTIFTITLE-QSPFLNSIGSDAFGGICR 237
            .:.:.||:.      |..|||.|....|..|:.|||||.:.:|.:: ::|.          |..:
  Fly   222 SSRKEVVSL------LLKGNKARTMEPTAANQTSSRSHALLSIMVQARTPL----------GTKQ 270

  Fly   238 GKLSLVDLAGSERQRKTGAQGDRLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQD 302
            |:|.|.|||||||.:||..:|.||:|.:.||.||.||||||:.| .|.|::|.:|||||||||::
  Fly   271 GRLFLTDLAGSERAKKTKNRGKRLQEGAHINRSLLALGNVINGL-SGGARYVNYRDSKLTRLLKE 334

  Fly   303 SLGGNTKTLMISCISPTDIHYDETISTLRYASRAKNISNKPKIN---EDPKDARLRQYQNEILYL 364
            :|.|..||:||:.::|...|.|||.:||.||.||.:|:.|.:.:   ::.||...:.||:.:..|
  Fly   335 ALSGRCKTVMIAHVAPESKHRDETKNTLVYADRANSITTKLQNSVYIDEFKDFPTKHYQSLVSEL 399

  Fly   365 K--------RMLQE---------------------------------------------SQQIIN 376
            :        :||.|                                             .:||:.
  Fly   400 RDEVSRLRTKMLTERPRSGAAAAAAAAAASGSAGTAGSGAGSEAVQEQDEQRKTELRYLREQIVL 464

  Fly   377 KNNDPNKIIKSPLKIIQH---TNMNSTKNVQIID-----LGRNCKA----SFKTNNSILTK---- 425
            ......|:.:..|:...|   ..:::.:...||.     :|:...|    ..::..|:..|
  Fly   465 TFKQQMKLRRKLLEAESHLLGLELDAERQHMIISHWQGRIGKLYDAMGDDDIESEGSVALKNAWG 529

  Fly   426 ---------PNFPLIQSKEEVQL-QARSRIDLIKRSLIGGERIHDFELKEKHMARKYAAQRHLSA 480
                     ..:..|:.:.|.:| |.|.:          |.::.| ||.|:..:.:   :|.|.|
  Fly   530 ELAAIEKETRRYKEIRERTEHELEQCRQK----------GVKLED-ELPERISSDE---ERELLA 580

  Fly   481 IAIALSRVKCEDRDLLQGHYATITQEIDIKNDYIRKCKEKIKMLEMEVSD---LNSEFQLDREDY 542
            :...:..::. |:..||........|:..::..:.:.:.:.::.|..:|.   |..|..:|..|.
  Fly   581 LLCRVHELEA-DKVSLQAERLARQAELRRRDLQLLRAERQRRLCEDIISSQRRLIEEGNVDLPDE 644

  Fly   543 LDEIRNLGRQVKFHQQLFLKFSSNPGKFDRNWTP 576
            |.|:..|.:| :.|..:....:||   ::|...|
  Fly   645 LRELYGLYQQ-EIHAGVVTPSTSN---YERKLPP 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	128/360 (36%)
Kif19A	NP_996208.1	Motor_domain	35..371	CDD:473979	127/359 (35%)
		SMC_prok_B	<393..672	CDD:274008	47/297 (16%)