Protein Alignment Kif3C and kif22

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_031748433.1
• Gene: kif22 / 394855
• XenbaseID: XB-GENE-979888
• Length: 680
• Species: Xenopus tropicalis
• Alignment Length: 571
• Identity: 172/571 - (30%)
• Similarity: 280/571 - (49%)
• Gaps: 110/571 - (19%)

  Fly     2 SENIKVVVRCRPMNQTEKERNCQNIVE-INEFAVSVTNPSARISQQKKFIFDSVY-NMKTDTEVI 64
            |..::|.||.||..:.|.|:.....|. ::..::.:.|...:: :..::.||:.| :..|..|:.
 Frog    29 SARVRVAVRLRPYMEKEDEKAPAACVRGLDSQSLEIVNWRNQL-ETMQYQFDAFYGDSATQREIY 92

  Fly    65 YDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERISMT---- 125
            ...:|:.|....| |.|.::||||.||.||||||.|:   .:..|:||:.   :.:.:.||
 Frog    93 MGSVCHILPHLLI-GQNASVFAYGPTGAGKTHTMLGN---PSQPGVIPRA---VRDLLQMTRTAA 150

  Fly   126 -----TNVRYLALVTYLEIYNERIRDLL---NK------NENTNVINHFLKELPGIGVSVPTLTT 176
                 .|..|...::|:|||.|::.|||   ||      :::.|::      :||:        |
 Frog   151 GGHENENWTYTITMSYVEIYQEKVMDLLEPKNKDLPIREDKDHNIL------IPGV--------T 201

  Fly   177 QPVVNANQCYDWLHF--GNKNRVTAATLMNKNSSRSHTIFTITLEQ----SPFLNSIGSDAFGGI 235
            |..:|:...:| .||  .::||..|:|.:|..|||||.:..|.:::    |||..
 Frog   202 QKTINSFGDFD-EHFIPASQNRTVASTKLNDRSSRSHAVLLIKVQKSQQVSPFRQ---------- 255

  Fly   236 CRGKLSLVDLAGSERQRKTGAQGDRLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLL 300
            ..|||.|:||||||..|:||.||.||||:..||.||..|..|:.:|..|..: :|:|||||||||
 Frog   256 LTGKLYLIDLAGSEDNRRTGNQGIRLKESGAINSSLFTLSKVVDALNQGLPR-IPYRDSKLTRLL 319

  Fly   301 QDSLGGNTKTLMISCISPTDIHYDETISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYLK 365
            ||||||...::||:.|:|...:|.:|::.|.:|:::|.|.|||...|..:...      .:..:|
 Frog   320 QDSLGGTAHSVMIANIAPEQKYYFDTLTALNFAAKSKQIINKPFSQETTQSIA------ALPAMK 378

  Fly   366 RMLQESQQII----NKNNDPNKIIKSPLKIIQHTNMNSTK----NVQIID---LGRNCKASFKTN 419
            |..:|::...    .|.:..:....||     :|:|::..    |:..:|   :.|..|.
 Frog   379 RPREEAETAAGSRQRKKSKTDSTESSP-----NTSMDAASKRKLNLAALDPAVVERLLKL----- 433

  Fly   420 NSILTKPNFPLIQSKEEVQLQA---RSRIDLIKR---SLIGGERIHDFELKEKHMARKYAAQRHL 478
            :.|||:      :..:|.||.:   |.|:.|:|:   |.:..||     ||||   :|...|:.:
 Frog   434 DKILTE------KGMKEAQLLSTPKRERMALLKKWEESQMEIER-----LKEK---QKELEQKAI 484

  Fly   479 SAIAIALSRVKCEDRDLLQGHYATITQEIDI--KNDYIRKCKEKIKMLEME 527
            .|.| .|.:....|.:|.....:..|....:  :|....|.|:.:::|.|:
 Frog   485 EAEA-RLEKSTNSDCNLSDSSVSECTFRAPLRGRNTSTAKAKKVLRVLPMQ 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	124/361 (34%)
kif22	XP_031748433.1	KISc_KID_like	31..356	CDD:276827	123/358 (34%)
		ComEA	617..666	CDD:441164