Protein Alignment Kif3C and Klp64D

DIOPT Version :9

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Alignment Length: 677
• Identity: 243/677 - (35%)
• Similarity: 363/677 - (53%)
• Gaps: 83/677 - (12%)

  Fly     3 ENIKVVVRCRPMNQTEKERNCQNIVEINEF--AVSVTNPSARISQ-QKKFIFDSVYNMKTDTEVI 64
            ||::||||.|||::.|......:.:.:::.  |::|..|:|..:: .|.:.||:|::..::...:
  Fly    19 ENVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATANEPPKTYYFDNVFDGGSNQMDL 83

  Fly    65 YDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERISMT-TNV 128
            |.:....:|:..:|||||||.||||||.|||:||.|:.:...:.||||..|.|||..|:.. .|.
  Fly    84 YVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAHIFGHIAKAKENQ 148

  Fly   129 RYLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNANQCYDWLHFGN 193
            ::|..|:|:|||||.:||||.|:...::   .:||.|.|||.|..|:...|.||:...:.:..||
  Fly   149 KFLVRVSYMEIYNEEVRDLLGKDVGKSL---EVKERPDIGVFVKDLSGYVVHNADDLENIMRLGN 210

  Fly   194 KNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAGSERQRKTGAQG 258
            |||...||.||:.|||||.||:||:|:|    .:|......:..|||.||||||||||.||.|.|
  Fly   211 KNRAVGATKMNQESSRSHAIFSITVERS----ELGEGDVQHVRMGKLQLVDLAGSERQSKTQASG 271

  Fly   259 DRLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKTLMISCISPTDIHY 323
            .|||||::||||||.||||||:|||||:.|:|:|:||||||||||||||:||:|.:.|||.|.:|
  Fly   272 QRLKEATKINLSLSVLGNVISALVDGKSTHIPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNY 336

  Fly   324 DETISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYLKRMLQESQQI-------INKNNDP 381
            .|||||||||||||||.|:..|||:||||.||.:|.||..|::.|:|...:       ..:.:..
  Fly   337 METISTLRYASRAKNIQNRMHINEEPKDALLRHFQEEIARLRKQLEEGDSLEEEPPSSEEEEDTA 401

  Fly   382 NKIIKSPLKI------IQHTNMNSTKNVQIIDLGRNCKASFKTNNSILTKPNFPLIQSKEEVQLQ 440
            :..:::||:|      ||.......|..:..|..:...|..|..:      ...:..:|.|.:..
  Fly   402 DDELEAPLEIELESSTIQAVEKKPKKKREKTDAEKEELAKRKNEH------QKEIEHAKTEQETL 460

  Fly   441 ARSRIDLIKRSLIGGERIHDFELKEKHMARKYAAQRHLSAIAIALSRVKCEDRDLLQGHYATITQ 505
            ....:.|..:.|:|||     .|.||...::...::.::    .|.:.:..:..|.|......|:
  Fly   461 RNKLVSLEGKILVGGE-----NLLEKAQTQELLLEQSIA----ELEQHEKSEEALKQTLQQKATE 516

  Fly   506 EIDIKNDY-------------IRKCKEKIKMLEMEVSDLNSEFQLDREDYLDEIRNLGRQVKFHQ 557
            .|||:..|             |.:..:.:..::.|::|...|.|.::|...:.||:|.|::...:
  Fly   517 RIDIEERYSTLQDASTGITKKIHRVMQMLMGVKSELADQQQEHQREKEGIYENIRSLSRELALCE 581

  Fly   558 QLFLKFSSNPGKFDRNWTPDTILQNSLWNDDLKMWRIPESDLIKLPPATQKSGLHCIHPLVIHSE 622
            .:...:.  |.::.     ..|.|.:.||:|:..|:                 |.|:       .
  Fly   582 LVLNSYV--PKEYQ-----SMINQYTHWNEDIGEWQ-----------------LKCV-------A 615

  Fly   623 NQHNNQNEIVVGEKVSISNIAFLFLSY 649
            ...||..:.:...|.|.....||.||:
  Fly   616 YTGNNMRKHISAHKTSGKEPDFLDLSH 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:277568	171/339 (50%)
		Kinesin	10..339	CDD:278646	166/332 (50%)
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	171/339 (50%)
		Kinesin	26..352	CDD:278646	166/332 (50%)
		RILP-like	<437..556	CDD:304877	23/133 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437693
Domainoid	1	1.000	253	1.000	Domainoid score	I504
eggNOG	1	0.900	-	-		E2759_KOG4280
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	250	1.000	Inparanoid score	I786
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D13740at7147
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.900