Protein Alignment Kif3C and KIFC1

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_054187052.1
• Gene: KIFC1 / 3833
• HGNCID: 6389
• Length: 674
• Species: Homo sapiens
• Alignment Length: 369
• Identity: 127/369 - (34%)
• Similarity: 181/369 - (49%)
• Gaps: 52/369 - (14%)

  Fly     4 NIKVVVRCRPMNQTEKERNCQNIVEINEFAVSVTNPSARISQQKK------------------FI 50
            ||:|..|.||:...|.... ..::.........::|..|:|..:.                  |.
Human   310 NIRVFCRVRPVLPGEPTPP-PGLLLFPSGPGGPSDPPTRLSLSRSDERRGTLSGAPAPPTRHDFS 373

  Fly    51 FDSVYNMKTDTEVIYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQ----GDENFSNSTGII 111
            ||.|:...:..:.:::|:. .||:|.::||...||||||||.|||.||:    ||....   |:|
Human   374 FDRVFPPGSGQDEVFEEIA-MLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPGGDPQLE---GLI 434

  Fly   112 PKCFDHIFERISMTTNV-----RYLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSV 171
            |:...|:|   |:...:     .|..:.:|:|||||.:||||.................|.|...
Human   435 PRALRHLF---SVAQELSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGECEIRRAGPGSEE 496

  Fly   172 PTLTTQ---PVVNANQCYDWLHFGNKNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFG 233
            .|:|..   ||....:....||...:||..|.|..|:.|||||::|.:.:.        |..:..
Human   497 LTVTNARYVPVSCEKEVDALLHLARQNRAVARTAQNERSSRSHSVFQLQIS--------GEHSSR 553

  Fly   234 GI-CRGKLSLVDLAGSERQRKTGAQG----DRLKEASQINLSLSALGNVISSLVDGKAKHVPFRD 293
            |: |...|||||||||||.....|.|    :||:|...||.|||.||.||.:| ..|..|||:|:
Human   554 GLQCGAPLSLVDLAGSERLDPGLALGPGERERLRETQAINSSLSTLGLVIMAL-SNKESHVPYRN 617

  Fly   294 SKLTRLLQDSLGGNTKTLMISCISPTDIHYDETISTLRYASRAK 337
            ||||.|||:||||:.|.||...|||.:.:..|::::||:||:.:
Human   618 SKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASKVR 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	127/369 (34%)
KIFC1	XP_054187052.1	SMC_prok_B	<138..>312	CDD:274008	1/1 (100%)
		KISc_C_terminal	308..661	CDD:276817	127/367 (35%)