Protein Alignment Kif3C and Klp61F

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_476818.1
• Gene: Klp61F / 38135
• FlyBaseID: FBgn0004378
• Length: 1066
• Species: Drosophila melanogaster
• Alignment Length: 619
• Identity: 201/619 - (32%)
• Similarity: 305/619 - (49%)
• Gaps: 86/619 - (13%)

  Fly     2 SENIKVVVRCRPMNQTEKERNCQNIVEINEFAVSVTNPSARISQQ-------KKFIFDSVYNMKT 59
            ::||:|.||.||:|..|:   |....|:    |.|..|...:::.       |||.||..:..::
  Fly    17 NQNIQVYVRVRPLNSRER---CIRSAEV----VDVVGPREVVTRHTLDSKLTKKFTFDRSFGPES 74

  Fly    60 DTEVIYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENF--------SNSTGIIPKCFD 116
            ....:|..:...|:|..:.|||.|:|||||||.||||||.|:|..        .:..||||:...
  Fly    75 KQCDVYSVVVSPLIEEVLNGYNCTVFAYGQTGTGKTHTMVGNETAELKSSWEDDSDIGIIPRALS 139

  Fly   117 HIFERISMTTNVRYLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVN 181
            |:|:.:.| ..|.|...::|||:|||.:.|||:.::.|. |..|........|.:..|...||.:
  Fly   140 HLFDELRM-MEVEYTMRISYLELYNEELCDLLSTDDTTK-IRIFDDSTKKGSVIIQGLEEIPVHS 202

  Fly   182 ANQCYDWLHFGNKNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLA 246
            .:..|..|..|.:.|.||.||||..||||||:|:|.:.    :...|.:....:..|||:|||||
  Fly   203 KDDVYKLLEKGKERRKTATTLMNAQSSRSHTVFSIVVH----IRENGIEGEDMLKIGKLNLVDLA 263

  Fly   247 GSERQRKTG-AQGDRLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKT 310
            |||...|.| .:|.|::|...||.||..||.||::||| :|.|||:|:||||||||:||||.|||
  Fly   264 GSENVSKAGNEKGIRVRETVNINQSLLTLGRVITALVD-RAPHVPYRESKLTRLLQESLGGRTKT 327

  Fly   311 LMISCISPTDIHYDETISTLRYASRAKNISNKPKINED-PKDARLRQYQNEILYLKRMLQESQQI 374
            .:|:.|||.....:||:|||.||.|||||.|||::|:. .|...|::|..||..|||.|..::
  Fly   328 SIIATISPGHKDIEETLSTLEYAHRAKNIQNKPEVNQKLTKKTVLKEYTEEIDKLKRDLMAAR-- 390

  Fly   375 INKNNDPNKII-------KSPLKIIQHTNMNSTKNVQIIDLGRNCKASFKTNNSILTKPNFPLIQ 432
                 |.|.|.       :..||:   .:.|...|.::: |.:..|...:....|.::.:..|::
  Fly   391 -----DKNGIYLAEETYGEITLKL---ESQNRELNEKML-LLKALKDELQNKEKIFSEVSMSLVE 446

  Fly   433 SKEEVQ------LQARSRIDLIKRSLIGGERIH--DFELKEKHMARKYA----AQRHLSAIAIAL 485
            ..:|::      |..:..:.|.|:.|...:|.:  ..||...||..:..    ||..|:|..:|.
  Fly   447 KTQELKKTEENLLNTKGTLLLTKKVLTKTKRRYKEKKELVASHMKTEQVLTTQAQEILAAADLAT 511

  Fly   486 S-------------------RVKCED-RDLLQGHYATITQEIDIKNDYIRKCKEKIKMLEMEVSD 530
            .                   |..|:. :|.:|.:...|...:::..|.....||::....:..|.
  Fly   512 DDTHQLHGTIERRRELDEKIRRSCDQFKDRMQDNLEMIGGSLNLYQDQQAALKEQLSQEMVNSSY 576

  Fly   531 LNSEFQLDREDYLDEIR-----NLGRQVKFHQQL 559
            ::....|:....::.::     :|..|...|.:|
  Fly   577 VSQRLALNSSKSIEMLKEMCAQSLQDQTNLHNKL 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	146/351 (42%)
Klp61F	NP_476818.1	KISc_BimC_Eg5	17..365	CDD:276815	152/361 (42%)
		SMC_prok_B	<408..728	CDD:274008	36/207 (17%)
		SMC_prok_B	<651..>921	CDD:274008
		Microtub_bind	923..>1004	CDD:464048