Protein Alignment Kif3C and KIFC3

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_006721251.1
• Gene: KIFC3 / 3801
• HGNCID: 6326
• Length: 1022
• Species: Homo sapiens
• Alignment Length: 350
• Identity: 132/350 - (37%)
• Similarity: 201/350 - (57%)
• Gaps: 32/350 - (9%)

  Fly     4 NIKVVVRCRPMNQTEKE----RNCQNIVEINEFAVSVTNPSARISQQKKFIFDSVYNMKTDTEVI 64
            ||:|:.|.||:.:.:.|    .|.......::..:.:.:....:|    |..|.|::.:...:.:
Human   634 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVS----FELDKVFSPQASQQDV 694

  Fly    65 YDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERI-SMTTNV 128
            :.|: .:||.|.|:|:|..||||||||.|||:||:|.   :.:.||..:....:|..: ...::.
Human   695 FQEV-QALVTSCIDGFNVCIFAYGQTGAGKTYTMEGT---AENPGINQRALQLLFSEVQEKASDW 755

  Fly   129 RYLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIG-VSVPTLT---TQPVVNANQCYDWL 189
            .|...|:..|||||.:||||.|.....:......:  |.| :.||.||   .|.|.:.|:.::
Human   756 EYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPD--GSGQLYVPGLTEFQVQSVDDINKVFE-- 816

  Fly   190 HFGNKNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGI-CRGKLSLVDLAGSERQRK 253
             ||:.||.|..|.:|::|||||.:..:|:.        |.|...|: ..|||:|||||||||..|
Human   817 -FGHTNRTTEFTNLNEHSSRSHALLIVTVR--------GVDCSTGLRTTGKLNLVDLAGSERVGK 872

  Fly   254 TGAQGDRLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKTLMISCISP 318
            :||:|.||:||..||.||||||:||::| ..:..|||||:||||.||||||.|::||||:..:||
Human   873 SGAEGSRLREAQHINKSLSALGDVIAAL-RSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSP 936

  Fly   319 TDIHYDETISTLRYASRAKNISNKP 343
            .:.:..||:.:|::|.|.:::...|
Human   937 VEKNTSETLYSLKFAERVRSVELGP 961

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	131/344 (38%)
KIFC3	XP_006721251.1	SMC_prok_B	294..>618	CDD:274008
		KISc_C_terminal	632..959	CDD:276817	131/346 (38%)