Protein Alignment Kif3C and Khc

DIOPT Version :9

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_476590.1
• Gene: Khc / 36810
• FlyBaseID: FBgn0001308
• Length: 975
• Species: Drosophila melanogaster
• Alignment Length: 652
• Identity: 197/652 - (30%)
• Similarity: 319/652 - (48%)
• Gaps: 107/652 - (16%)

  Fly     3 ENIKVVVRCRPMNQTEKERNCQNIVE----INEFAVSVTNPSARISQQKKFIFDSVYNMKTDTEV 63
            ::||||.|.||:|.:|::...:.:|:    :.|..:|:..        |.::||.|:......|.
  Fly    11 DSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIAG--------KVYLFDKVFKPNASQEK 67

  Fly    64 IYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERI-SMTTN 127
            :|:|...|:|...:.||||||||||||..||||||:|....|...||||:..:.||..| :|..|
  Fly    68 VYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQGIIPRIVNDIFNHIYAMEVN 132

  Fly   128 VRYLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNANQCYDWLHFG 192
            :.:...|:|.|||.::|||||:.::....::.....:|.:..:.....:.|    ...::.:..|
  Fly   133 LEFHIKVSYYEIYMDKIRDLLDVSKVNLSVHEDKNRVPYVKGATERFVSSP----EDVFEVIEEG 193

  Fly   193 NKNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAGSERQRKTGAQ 257
            ..||..|.|.||::|||||::|.|.::|....|.       ....|||.||||||||:..||||:
  Fly   194 KSNRHIAVTNMNEHSSRSHSVFLINVKQENLENQ-------KKLSGKLYLVDLAGSEKVSKTGAE 251

  Fly   258 GDRLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKTLMISCISPTDIH 322
            |..|.||..||.||||||||||:|.||...|:|:|||||||:||:|||||.:|.::.|.||...:
  Fly   252 GTVLDEAKNINKSLSALGNVISALADGNKTHIPYRDSKLTRILQESLGGNARTTIVICCSPASFN 316

  Fly   323 YDETISTLRYASRAKNISNKPKINED--------------PKDARLRQYQNEI-LYLKR-----M 367
            ..||.|||.:..|||.:.|...:||:              .|:|||:....:: :.|.|     .
  Fly   317 ESETKSTLDFGRRAKTVKNVVCVNEELTAEEWKRRYEKEKEKNARLKGKVEKLEIELARWRAGET 381

  Fly   368 LQESQQI----INKNNDPNKIIKS-------PLKIIQHTNM-NSTKNVQIID---LGRNCKASFK 417
            ::..:||    :.:.:.||..:::       .....|.|.: |.:.:|.:.:   |...|:..::
  Fly   382 VKAEEQINMEDLMEASTPNLEVEAAQTAAAEAALAAQRTALANMSASVAVNEQARLATECERLYQ 446

  Fly   418 TNNSILTKPNFPLIQSKEEVQLQARSRIDLIKRSLIGGERI-----HDFELKEKHMARKYAAQRH 477
            .            :..|:|...|.....:.:|..::..|.:     .::|..:..|||  ..|.:
  Fly   447 Q------------LDDKDEEINQQSQYAEQLKEQVMEQEELIANARREYETLQSEMAR--IQQEN 497

  Fly   478 LSAIAIALSRVKCEDRDLLQG------HYATITQEIDIKNDYIRKCKEKIKMLEMEVSDLNSEFQ 536
            .||        |.|.:::||.      :|...:||||.||..|....|:::..:...:..::|.|
  Fly   498 ESA--------KEEVKEVLQALEELAVNYDQKSQEIDNKNKDIDALNEELQQKQSVFNAASTELQ 554

  Fly   537 LDREDYLDEIRNL-GRQVKFHQQLFLKFSSNPGKFDRNWTPDTILQNSLWNDDLKMWRIPESDLI 600
                    ::::: ..|.|...::......:.|:..:...|.   ::|:   ||||..:..:|..
  Fly   555 --------QLKDMSSHQKKRITEMLTNLLRDLGEVGQAIAPG---ESSI---DLKMSALAGTDAS 605

  Fly   601 KL 602
            |:
  Fly   606 KV 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:277568	140/340 (41%)
		Kinesin	10..339	CDD:278646	136/333 (41%)
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	140/340 (41%)
		KISc	12..340	CDD:214526	141/346 (41%)
		Apolipoprotein	595..744	CDD:279749	4/13 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437709
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D24620at33392
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950