Protein Alignment Kif3C and Kif18a

DIOPT Version :9

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_038961378.1
• Gene: Kif18a / 362186
• RGDID: 1561740
• Length: 886
• Species: Rattus norvegicus
• Alignment Length: 713
• Identity: 209/713 - (29%)
• Similarity: 317/713 - (44%)
• Gaps: 191/713 - (26%)

  Fly     1 MSENIKVVVRCRPMNQTEKERNCQNIVEINEFAVSVTNP------------------SARISQQK 47
            :..::|||||.||.|..||......:|.:.:..:.|.:|                  :.|.::..
  Rat     8 LCHHMKVVVRVRPENTKEKAVQFHKVVHVVDKHILVFDPKQEEISFFHRKKTTNFDITKRQNKDL 72

  Fly    48 KFIFDSVYNMKTDTEV-IYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGI- 110
            ||:||:|:: :|.|:: :::.....::.|.:.|||.|:||||.||.||||||.|.   :...|:
  Rat    73 KFVFDAVFD-ETSTQMEVFEHTTKPILHSFLNGYNCTVFAYGATGSGKTHTMLGS---TAEPGVM 133

  Fly   111 ------IPKCFDHIFERISMTTNVRYLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGV 169
                  :.||.|.:.:....:|      .|:|||:|||:|||||     ||.....::|....||
  Rat   134 YLTMLDLFKCMDEVKDEKECST------AVSYLEVYNEQIRDLL-----TNSGPLAVREDAQKGV 187

  Fly   170 SVPTLTTQPVVNANQCYDWLHFGNKNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGG 234
            .|..||.....::.:....|..|||||....|.||..|||||.:|.|.|.|.....||..:
  Rat   188 VVQGLTLHQPKSSEEILQLLDNGNKNRTQHPTDMNAASSRSHAVFQIYLRQQDKTASINQN---- 248

  Fly   235 ICRGKLSLVDLAGSERQRKTGAQGDRLKEASQINLSLSALGNVISSLVDGKAK--HVPFRDSKLT 297
            :...|:||:|||||||...:|.:|.|..|.:.||.||.||||||::|.|.|.:  |:|:|:||||
  Rat   249 VHIAKMSLIDLAGSERASISGTKGTRFVEGTNINKSLLALGNVINALADTKRRNQHIPYRNSKLT 313

  Fly   298 RLLQDSLGGNTKTLMISCISPTDIHYDETISTLRYASRAKNI-SNKPKINEDPKDARLRQY---- 357
            |||:||||||.:|:||:.:||:.:.||:|.:||:||:|||:| |::.|.|.....:.:.||
  Rat   314 RLLKDSLGGNCQTIMIAAVSPSSLFYDDTYNTLKYANRAKDIKSSQLKSNVVNLSSHISQYVKIC 378

  Fly   358 ---QNEILYLKRMLQ--ESQQIINKNNDPNKIIKSPLKIIQHTNMNSTKNVQIIDLGRNCKASFK 417
               :.|||.||..|:  |.|:.:...||..|::        |:|:.. |.::......||
  Rat   379 NMQKAEILMLKEKLKAYEGQKALTDRNDCAKLV--------HSNVED-KEIERFQEILNC----- 429

  Fly   418 TNNSILTKPNFPLIQSKEEVQLQARSRIDLIKRSLIGGERIHDFELKEKHMARKYAAQRHLSAIA 482
                        |.|::|.:: |...:::::              |||..:...|..|.| ..|.
  Rat   430 ------------LFQNREGMR-QEYLKVEML--------------LKENELKSSYHQQCH-KQIE 466

  Fly   483 IALSRVKCEDRDLLQGHYATITQEIDIKNDYIRKCKEKIKMLEMEVSDLNSEFQLDREDYLDEIR 547
            :..|..|.|.....:.|             .:.|.|....:||.:..::..:|        ||..
  Rat   467 MMCSEDKLEKATCRRDH-------------RLEKLKSNRCVLEKKKEEMLKQF--------DENT 510

  Fly   548 NLGRQVKFHQQLFLKFSSNPGKFDRNWTPDTILQNSLWNDDLKMWRIPESDLIKLPPATQKSGLH 612
            |...:|:...:|.       |:                |.|     |||.         ....||
  Rat   511 NWLHRVESEMRLL-------GQ----------------NGD-----IPEG---------LNKDLH 538

  Fly   613 CIHPLVIHSEN------------------QHNNQNEIVVG-------------EKVSISNIAF 644
            |.|   :|.:|                  |.:.|.|.|:.             ::..:||.||
  Rat   539 CHH---LHLQNKDLKTQMGHMMTLAALQEQQHGQTEAVLNALLPVLRKQYWRLKETGLSNAAF 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:277568	142/363 (39%)
		Kinesin	10..339	CDD:278646	138/356 (39%)
Kif18a	XP_038961378.1	KISc_KIP3_like	11..355	CDD:276821	142/362 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910