Protein Alignment Kif3C and Kif14

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001414162.1
• Gene: Kif14 / 360849
• RGDID: 1310650
• Length: 1672
• Species: Rattus norvegicus
• Alignment Length: 679
• Identity: 192/679 - (28%)
• Similarity: 300/679 - (44%)
• Gaps: 157/679 - (23%)

  Fly     2 SENIKVVVRCRPMNQTEKERNCQNIVEINEFAVSVTNPSARISQQKKFIFDSVY----------- 55
            :..:.|.||.||.::.||......:|..|...::|.:|.  :.|...||:|..:
  Rat   391 NSQVTVAVRVRPFSKREKTEKASQVVFRNGEEITVEHPD--MKQIYSFIYDVAFWSFDECHPGYA 453

  Fly    56 NMKTDTEVIYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFE 120
            |..|    :|:.:...|::...||||..:|||||||.||::||.|   .:...||||:..:.:|.
  Rat   454 NQTT----VYETLAAPLLDRAFEGYNTCLFAYGQTGSGKSYTMMG---LNEEPGIIPRFCEDLFA 511

  Fly   121 RIS--MTTNVRYLALVTYLEIYNERIRDLL-NKNENTNVINHF-LKELPGIGVSVPTLTTQPVVN 181
            :|:  ..:.|.|...:::.|:|||:|.||| .|.||....... ::|.|..|..|..|:...|.:
  Rat   512 QIAKKQASEVSYHLEMSFFEVYNEKIHDLLVCKGENGQRKQPLRVREHPVSGPYVEGLSMNVVSS 576

  Fly   182 ANQCYDWLHFGNKNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLA 246
            .:....||..|||.|.||||.||..|||||::||:.:.|:. ...:..:........:::|:|||
  Rat   577 YSDIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTK-TEFVEGEEHDHRITSRINLIDLA 640

  Fly   247 GSERQRKTGAQGDRLKEASQINLSLSALGNVISSL---VDGKAKHVPFRDSKLTRLLQDSLGGNT 308
            ||||.....:.|:||||...||.||..||.|||:|   .:||...:|:|:|.||.||::|||||:
  Rat   641 GSERCSTAHSSGERLKEGVSINKSLLTLGKVISALSEQANGKRVFIPYRESTLTWLLKESLGGNS 705

  Fly   309 KTLMISCISPTDIHYDETISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYLKRMLQESQQ 373
            ||.||:.|||...:.:||:||||||::|:.|.|..|:|||.....:|:.:.||..||     :.|
  Rat   706 KTAMIATISPAASNIEETLSTLRYATQARLIVNVAKVNEDMNAKLIRELKAEIEKLK-----AAQ 765

  Fly   374 IINKNNDPNKIIKSPLKIIQHTNMNSTKNVQIIDLGRNCKASFKTNNSILTKPNFPLIQSKEEVQ 438
            ..::|.||.:.                         |.|:...                |...::
  Rat   766 KSSRNIDPERY-------------------------RLCRQEI----------------SSLRMK 789

  Fly   439 LQARSRIDLIKRSLIGGERIHDFELKEKHMARKYAAQRHLSAIAIALSRVKCEDRDLLQGHYATI 503
            |..:.| |:.:...:..|:   ||..||
  Rat   790 LHQQER-DMAEIQRVWKEK---FEQAEK------------------------------------- 813

  Fly   504 TQEIDIKNDYIRKCKEKIKMLEMEVSDLNSEFQLDREDYLDEIRNLGRQVKFHQQLFLKFS---S 565
                       ||.:|..::.:..|:     ||:|  ::|..:.||....:..:.|.....   :
  Rat   814 -----------RKLQETKELQKAGVT-----FQMD--NHLPNLVNLNEDPQLSEMLLYMVKEGIT 860

  Fly   566 NPGKFDRNWTPDTILQNSLWNDD---LKMWRIPESDLIKLPPA----TQKSGLHCIHPLVIHSEN 623
            ..||...|.:.|..|...|..||   ::.:    ...:.:.||    |..:|:|...|.|:|..:
  Rat   861 TVGKHTPNSSHDIQLSGVLIADDHCTIRSY----GGTVSIVPAGEAKTYVNGMHISEPTVLHHGD 921

  Fly   624 ----------QHNNQNEIVVGEKVSISNI 642
                      :.|:..|:..|:|.|.:|:
  Rat   922 RVVLGGDHYFRFNHPVEVQKGKKTSRNNL 950

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	133/353 (38%)
Kif14	NP_001414162.1	None