Protein Alignment Kif3C and klp-20

DIOPT Version :9

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_497178.1
• Gene: klp-20 / 3565057
• WormBaseID: WBGene00002230
• Length: 646
• Species: Caenorhabditis elegans
• Alignment Length: 670
• Identity: 256/670 - (38%)
• Similarity: 373/670 - (55%)
• Gaps: 109/670 - (16%)

  Fly     2 SENIKVVVRCRPMNQTEKERNCQNIVEIN--EFAVSVTNPSARISQQ---KKFIFDSVYNMKTDT 61
            :|.:||||||||::.|||.:..:..|..|  |.||::.:    :||:   :.|.||:|::..||.
 Worm     4 AEKVKVVVRCRPISTTEKLQGHKIAVTCNDEEKAVNIKS----LSQEDPPRTFYFDAVFSPNTDQ 64

  Fly    62 EVIYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERISMTT 126
            ..:|:.....:||:.::|||||||||||||.|||.||.||.......||||..|.|||:.|:...
 Worm    65 MTVYNVAARPIVENVLKGYNGTIFAYGQTGTGKTFTMAGDLEPVEMRGIIPNSFAHIFDHIAKCQ 129

  Fly   127 -NVRYLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNANQCYDWLH 190
             :..:|..|:|||||||.|||||:|:.|.|:   .:||.|.:||.|..|:...|.||::....:.
 Worm   130 HDTTFLVRVSYLEIYNEEIRDLLSKDHNGNL---EIKERPDVGVYVRNLSNPTVENASKMQALME 191

  Fly   191 FGNKNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAGSERQRKTG 255
            ||:|||...||.||..|||||.:||:|:|         |...|.:.:|||.||||||||||.|||
 Worm   192 FGSKNRKVGATAMNLESSRSHAMFTVTIE---------SCRNGLVTQGKLQLVDLAGSERQSKTG 247

  Fly   256 AQGDRLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKTLMISCISPTD 320
            |||:|||||::||||||.||||||||||||:.|:|:|:||||||||||||||:||:||:.:.|..
 Worm   248 AQGERLKEAAKINLSLSTLGNVISSLVDGKSTHIPYRNSKLTRLLQDSLGGNSKTVMIANVGPAT 312

  Fly   321 IHYDETISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYLKRMLQESQQIINKNNDPNKII 385
            .:||||:||||||:|||||.|..|||||||||:||::|.||..|:::|.|.    |..:|.|:..
 Worm   313 YNYDETLSTLRYANRAKNIQNVAKINEDPKDAQLRKFQLEIEALRKILDEE----NPGDDENQEE 373

  Fly   386 KSPLKIIQHTNMNSTKNVQIIDLGRNCKASFKTNNSILTKPNFPLIQS--KEEVQL--------Q 440
            ....| :|...:...|..:|::        .:.|:::..:....|::.  :.|.:|        :
 Worm   374 AWEAK-MQEREVEMEKKRKILE--------ERVNSAVNDEETHRLVKEMMENEAELKKARSEHEK 429

  Fly   441 ARSRIDLIKRSLI-GGERIHD--------FELKEKHMARKYAAQRHLSAIAIALSRVKCEDRDLL 496
            .||:::.|::.|| |||.:.:        .|:..|.:.:....:.||.......:.||.|    :
 Worm   430 LRSKLEKIEKKLIVGGENLLEKVEEQAKLLEVNNKELEQSKFQEAHLRTQLEERTAVKVE----I 490

  Fly   497 QGHYATITQEIDIKNDYIRKCKEKIKMLEMEVSDLNSEFQLDREDYLDEIRNLGRQVKF------ 555
            :..|:::.:|..:|:..|:|...::|....|:.||..:.|...|..||:||.|.:::..
 Worm   491 EERYSSLQEEAFVKSKKIKKVSNELKDARAELKDLEEDHQRQVEAMLDDIRQLRKELLLNIAIID 555

  Fly   556 ------HQQLFLKFSSNPGKFDRNWTPDTILQNSLWNDDLKMWRIP------ESDLIKLPPATQK 608
                  |.:|..|:.|                   |:::...|::.      .:.....|||.:
 Worm   556 EYIPVEHVELIEKYVS-------------------WSEEHGDWQLKAIAYTGNNMRASAPPAKK- 600

  Fly   609 SGLHCIHPLVIHSENQHNNQ 628
                         |..:|||
 Worm   601 -------------EFSNNNQ 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:277568	181/341 (53%)
		Kinesin	10..339	CDD:278646	176/334 (53%)
klp-20	NP_497178.1	Motor_domain	5..331	CDD:328930	181/341 (53%)
		SMC_N	<325..>569	CDD:330553	68/260 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4280
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145782at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820