Protein Alignment Kif3C and Kif6

DIOPT Version :9

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_796026.2
• Gene: Kif6 / 319991
• MGIID: 1098238
• Length: 802
• Species: Mus musculus
• Alignment Length: 705
• Identity: 184/705 - (26%)
• Similarity: 289/705 - (40%)
• Gaps: 194/705 - (27%)

  Fly     1 MSENIKVVVRCRP-----------MNQTEKERNCQNIVEINEFAVSVTNPSARISQQKKFIFDSV 54
            :.:.|::..|.:|           :::.||..:...||...:.|....|..   .:..||.|..:
Mouse     2 VKQTIQIFARVKPTVRKQQQGIYSIDEDEKLTHSLEIVLPRDLADGFVNNK---RESYKFKFQRI 63

  Fly    55 YNMKTDTEVIYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIF 119
            ::.:...|:|::.:...:.|||:.|||||||||||||.|||.|:.|.....:..||||:...:||
Mouse    64 FDQEAKQEIIFEIIAKPVAESTLAGYNGTIFAYGQTGSGKTFTITGGAERYSDRGIIPRTLSYIF 128

  Fly   120 ERISMTTNVRYLALVTYLEIYNERIRDLLNKNENTNVINHFLK----ELPGIGVSVPTLTTQPVV 180
            |::...::..|...::|||||||...|||:.....:.:....|    |.|...:.:..|:.....
Mouse   129 EQLQKDSSKIYTTHISYLEIYNECGYDLLDPRHEASKLEDLPKVTILEDPDQNIHLKNLSLHQAT 193

  Fly   181 NANQCYDWLHFGNKNRVTAATLMNKNSSRSHTIFTITL-EQSPFLNSIGSDAFGGICRGKLSLVD 244
            ...:..:.|..|:.||:.|.|.||:.|:|||.|||:.| .:.|     ||   ..:...||.|||
Mouse   194 TEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTVHLSSKEP-----GS---ATVRHAKLHLVD 250

  Fly   245 LAGSERQRKTGAQGDRLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTK 309
            ||||||..|||..|..|.||..|||||..|..||.:|.:....|:|:|:|.:|.:|:||||||..
Mouse   251 LAGSERVSKTGVGGLLLTEAKYINLSLHYLEQVIIALSEKHRTHIPYRNSMMTSVLRDSLGGNCM 315

  Fly   310 TLMISCISPTDIHYDETISTLRYASRAKNISNKPKINE--DPK---------------------- 350
            |.||:.:|....:.||:|||.|:|.|...|.|:..:||  ||:
Mouse   316 TTMIATLSLEKRNIDESISTCRFAQRVALIKNEAILNEEIDPRLMIVRLQKEIEDLKAELAMATG 380

  Fly   351 --------DARLRQYQNEIL--------------------------YLKRMLQESQQIIN--KNN 379
                    :|.|.|.:..|.                          :.|::|.:.:.:.|  .:.
Mouse   381 EQRTEALTEAELLQLEKLIASYLEDQDPESRLEVGADMRKIHHCFHHFKKLLNDKKTLENTVSSE 445

  Fly   380 DPNKIIKSPLKIIQHTNM-------NSTKNVQIIDLGRNCKASFKT----NNSIL----TKP--N 427
            ...:..:.||:..::|.:       ::..|:.:..|.:..|   ||    .||.|    |:|  |
Mouse   446 STRQACQEPLRDEEYTKLLGLLKQRDNEINILVNMLKKEKK---KTQDALQNSSLEKSDTRPPQN 507

  Fly   428 FPLIQS-----------------------------------KEEVQLQARSRIDLIKRSLIGGER 457
            .|.|..                                   :||:.|..:...::.||.......
Mouse   508 SPFIAGSPAVPRTPFSSAPSHTQDLSICRHRSSLLHKKTGMREEMSLGRQEAFEIFKRDHADSVT 572

  Fly   458 IHDFE--LKEKHMARKYAA------------------QRHLSAIAIALS---------------- 486
            |.|.:  ||::....|...                  ||||..:|:.:|
Mouse   573 IEDNKQVLKQRFSEAKALGESINEARSKIGQLKDAINQRHLQQVALGISENTVPASTPDPQEEKL 637

  Fly   487 RVKCEDRDLLQGHYATI-----TQEIDIKNDYIRKCKEKIKMLEMEVSDLNSEFQ 536
            |.:.|:.   :|.|.|.     ..:::|::..:...|.|:|        |..||:
Mouse   638 RAQLEEE---KGRYKTAFMHLKALKVEIEHLQLLMDKAKVK--------LQKEFE 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:277568	127/351 (36%)
		Kinesin	10..339	CDD:278646	126/344 (37%)
Kif6	NP_796026.2	KISc_KIF9_like	5..343	CDD:276826	127/348 (36%)
		Kinesin	11..345	CDD:278646	126/344 (37%)
		Cob_adeno_trans	<350..>408	CDD:294596	8/57 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4280
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810