DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kif3C and Kif26a

DIOPT Version :9

Sequence 1:	NP_651939.4	Gene:	Kif3C / 43820	FlyBaseID:	FBgn0039925	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	XP_006240697.1	Gene:	Kif26a / 314473	RGDID:	1307957	Length:	1881	Species:	Rattus norvegicus

Alignment Length:	370	Identity:	99/370 - (26%)
Similarity:	175/370 - (47%)	Gaps:	45/370 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IKVVVRCRPMNQTEKERNCQNIVEINEFAVSVT----------------NPSARISQQKKFIFDS 53
            :||::|..|....::.....:.::::.....||                .|:|.:  .|.|.||:
  Rat   365 VKVMLRIWPAQGVQRSAESTSFLKVDSRKKQVTLYDPAAGPPGCAGLRHAPTAPV--PKMFAFDA 427

  Fly    54 VYNMKTDTEVIYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHI 118
            ::...::...:.......:::|.:.|.:|.||::|....||::||.|.::...|.||:|.....:
  Rat   428 IFPQDSEQAEVCSGTVADVLQSVVGGADGCIFSFGHMSLGKSYTMIGKDSSPQSLGIVPCAISWL 492

  Fly   119 F-------ERISMTTNVRYLALVTYLEI--YNERIRDLLNK-----NENTNVINHFLKELPGIGV 169
            |       ||:....::|    |:.:|:  :::.:||||.:     .::|.....:|:|.|..|.
  Rat   493 FRLIDERKERLGTRFSIR----VSAVEVCGHDQSLRDLLAEVASGCLQDTQSPGVYLREDPVCGT 553

  Fly   170 SVPTLTTQPVVNANQCYDWLHFGNKNRVTAATLMNKNSSR-SHTIFTITLEQSPFLNSIGSDAFG 233
            .:..........|.:...:|......|.|:.....:::.| ||.:||:.:.|.. :...|.....
  Rat   554 QLRNQNELRAPTAEKAAFYLDAALAARSTSRAGCGEDARRTSHMLFTLHVYQYR-VEKCGQGGMS 617

  Fly   234 GICRGKLSLVDLAGSERQRKTGAQGDRLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTR 298
            | .|.:|.|:||...|.....|.:.    ....:.|||||||:||.:||:| |||||:||..||.
  Rat   618 G-GRSRLHLIDLGSCEAAPSRGGEA----SGGPLCLSLSALGSVILALVNG-AKHVPYRDHTLTM 676

  Fly   299 LLQDSLGGNT-KTLMISCISPTDIHYDETISTLRYASRAKNISNK 342
            ||::||...: .|.||:.||.:..|:.||:||::.|:|...:..|
  Rat   677 LLRESLATTSCCTTMIAHISDSPTHHAETLSTVQLAARIHRLRRK 721

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:277568	98/365 (27%)
Kif3C	NP_651939.4	Kinesin	10..339	CDD:278646	96/360 (27%)
Kif26a	XP_006240697.1	KISc	364..716	CDD:276812	98/363 (27%)
		KISc	365..725	CDD:214526	99/370 (27%)
		PRK07764	<837..1309	CDD:236090
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4280
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900