Protein Alignment Kif3C and Kif12

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_006238315.1
• Gene: Kif12 / 313254
• RGDID: 1308487
• Length: 648
• Species: Rattus norvegicus
• Alignment Length: 483
• Identity: 150/483 - (31%)
• Similarity: 232/483 - (48%)
• Gaps: 67/483 - (13%)

  Fly     5 IKVVVRCRPMNQTEKERNCQNIVEIN-EFAVSVTNPSARISQQKKFIFDSVYN-MKTDTEVIYDE 67
            |:||:|.|||:..|..|..|:.:..: ...:.|:.|..  .....|.|.:|.: .:|..:|....
  Rat    26 IQVVLRVRPMSTVELRRGEQSALHCSGTRTLQVSPPGG--GPDVAFRFGAVLDGARTQEDVFRAC 88

  Fly    68 MCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNS-------TGIIPKCFDHIFERIS-M 124
            ....|.|..:.|::.|:|.:||||.|||:|:.|....:..       .||:.:.|..:.:|:. :
  Rat    89 GVKRLGELALRGFSCTVFTFGQTGSGKTYTLTGPPPQAEGVPVPPSLAGIMQRTFTWLLDRMQHL 153

  Fly   125 TTNVRYLALVTYLEIYNERIRDLLNKNENTNVINHFLKELP-----GIGVSVPTLTTQPVVNANQ 184
            .:.|...|  :|||||||:::|||::...        :.||     ..|..|..|......:...
  Rat   154 DSPVTLRA--SYLEIYNEQVQDLLSQGSP--------RPLPVRWSKARGFYVEQLRLVECGSLEA 208

  Fly   185 CYDWLHFGNKNRVTAATLMNKNSSRSHTIFTI-----TLEQSPFLNSIGSDAFGGICRGKLSLVD 244
            ..:.|..|...|.:::..:|:.|||||.:.|:     |.:|.|.:: :|....|    |||..||
  Rat   209 LMELLQMGLSRRRSSSHTLNQASSRSHALLTLHISRPTSQQVPPVD-LGEPPVG----GKLCFVD 268

  Fly   245 LAGSERQRKTGAQGDRLKEASQINLSLSALGNVISSLVDGKAK--HVPFRDSKLTRLLQDSLGGN 307
            |||||:...||::|..:.||:.||.||.|||:.||.|:|.:.|  |:||||||||:||.|||||.
  Rat   269 LAGSEKVAATGSRGQLMLEANSINRSLLALGHCISLLLDPQRKQSHIPFRDSKLTKLLADSLGGR 333

  Fly   308 TKTLMISCISPTDIHYDETISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYLKRMLQESQ 372
            ..|||::|:||:.....||:|||||||||:.|:.:|:..:.|.....:|.:.|:|    .|||..
  Rat   334 GVTLMVACVSPSAQCLPETLSTLRYASRAQRITTRPQGPKSPAVKPPQQVEAELL----QLQEEN 394

  Fly   373 QIINKNNDPNKIIKSPLKIIQHTNMNSTKNVQIIDLGRNCKA---SFKTNNSILTKPNFPLIQSK 434
            :.:....|.           .:|........::....||...   .|...|..|.|....|..|:
  Rat   395 RCLRLQLDQ-----------MYTKAPRVHGARVAWAQRNLYGMLQEFMLENEKLRKEMRQLRSSR 448

  Fly   435 EEVQLQARSRIDLIKRSLIGGERIHDFE 462
            :..|.:..          :..::||:.|
  Rat   449 DLAQAEQH----------VLAQQIHELE 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	127/355 (36%)
Kif12	XP_006238315.1	KISc	25..363	CDD:276812	126/353 (36%)