Protein Alignment Kif3C and Kif13b

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001398965.1
• Gene: Kif13b / 305967
• RGDID: 1303307
• Length: 1843
• Species: Rattus norvegicus
• Alignment Length: 796
• Identity: 225/796 - (28%)
• Similarity: 340/796 - (42%)
• Gaps: 227/796 - (28%)

  Fly     5 IKVVVRCRPMNQTEKERNCQNIVEI-------NEFAVSVTNPSARISQQKKFIFD--------SV 54
            :||.||.||||:.|.:.:.:.:|::       |....:::...|| .|.|.|.:|        ||
  Rat     6 VKVAVRVRPMNRREIDLHTKCVVDVEANKVILNPINTNLSKGDAR-GQPKIFAYDHCFWSMDESV 69

  Fly    55 YNMKTDTEVIYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIF 119
            .......:.::..:..:::::..:|||..||||||||.||::||.|.   ::..|:||:....:|
  Rat    70 REKYAGQDDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGT---ADQPGLIPRLCSGLF 131

  Fly   120 ERISMTTNVR--YLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNA 182
            ||.....|..  :...|:|:|||||::||||:...:...:.  ::|...:|..|..|:...|.:.
  Rat   132 ERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLK--VREHSVLGPYVDGLSKLAVTSY 194

  Fly   183 NQCYDWLHFGNKNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAG 247
            ......:..|||:|..|||.||:.|||||.:|.|||..:.:....|:   .|...||||||||||
  Rat   195 KDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSGT---SGEKVGKLSLVDLAG 256

  Fly   248 SERQRKTGAQGDRLKEASQINLSLSALGNVISSLVD-----GKAKHVPFRDSKLTRLLQDSLGGN 307
            |||..||||.||||||.|.||.||:.||.|||:|.|     .|.|.||:|||.||.||:||||||
  Rat   257 SERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQGAGKNKNKFVPYRDSVLTWLLKDSLGGN 321

  Fly   308 TKTLMISCISPTDIHYDETISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYLKRML---- 368
            :||.|::.:||...:||||:||||||.|||:|.|...:||||....:|..:.|:..|:..|
  Rat   322 SKTAMVATVSPAADNYDETLSTLRYADRAKHIINHAVVNEDPNARIIRDLREEVEKLREQLTKAE 386

  Fly   369 ------------------------------------QESQQ----------------------II 375
                                                ||.|:                      ::
  Rat   387 AMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQTSGIKVGDDKCFLV 451

  Fly   376 NKNNDP--NKIIKSPLKIIQHTNMNS--TKNVQIIDLG---------------------RNCK-- 413
            |.|.||  |:::...||  :||.:.|  ::::|:..:|                     :|.:
  Rat   452 NLNADPALNELLVYYLK--EHTLIGSANSQDIQLCGMGILPEHGIIDIMPEGQVMLTPQKNTRTF 514

  Fly   414 ---------------------------------------------ASFKTNNS------------ 421
                                                         ||.|.::|
  Rat   515 VNGSSVSSPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEEREASLKNDSSSEQLDADGDSSS 579

  Fly   422 -ILTKPNFPLIQSKEEVQLQARSRIDLIKRSLIGGERIHDFELKEKHMARKYAAQRHLSAIAIAL 485
             :.::.||....::.||.::|....|.::..|...|:.|:.|.:.....::...:..|..:...|
  Rat   580 EVSSEINFNFEYAQMEVTMKALGSNDPMQSILSSLEQQHEEEKRSALERQRLMYEHELEQLRRRL 644

  Fly   486 S--RVKCEDRDLLQGHYATITQ---------EIDIKNDYIRKCKEKIK--MLEMEVSDLNSEFQL 537
            |  |..|...|.|..|..:..|         |..:.|..:|..::.:|  :|..|.|.:..|  |
  Rat   645 SPERQNCRGVDRLSFHSPSAQQRLRQWAEEREATLNNSLMRLREQIVKANLLVREASYIAEE--L 707

  Fly   538 D-REDY----------LDEIRNLGR-------QVKFHQQLFLKFSSNPGKFDRNWTPDTILQNSL 584
            | |.:|          ||..|..|.       ||:           ..||..:.|:.:. |:|.|
  Rat   708 DKRTEYKVTLQIPASSLDANRKRGSLLSEPAIQVR-----------RKGKGKQIWSLEK-LENRL 760

  Fly   585 --WNDDLKMWRIPESD 598
              ..|..:.|:..|.|
  Rat   761 LDMRDLYQEWKECEED 776

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	148/355 (42%)
Kif13b	NP_001398965.1	KISc_KIF1A_KIF1B	4..360	CDD:276816	150/362 (41%)
		Kinesin_assoc	357..469	CDD:465047	18/113 (16%)
		FHA_KIF13B	447..545	CDD:438782	13/99 (13%)
		COG4913	<614..>760	CDD:443941	35/159 (22%)
		KIF1B	756..802	CDD:463574	7/21 (33%)
		C2-C2_1	<888..>952	CDD:463310
		bMERB_dom	<1073..1143	CDD:463467
		DUF3694	<1214..1277	CDD:463599
		PHA03247	<1377..1715	CDD:223021
		CAP_GLY	1720..1783	CDD:460154