DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kif3C and Kif26b

DIOPT Version :9

Sequence 1:	NP_651939.4	Gene:	Kif3C / 43820	FlyBaseID:	FBgn0039925	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	XP_038946745.1	Gene:	Kif26b / 305012	RGDID:	1560022	Length:	2138	Species:	Rattus norvegicus

Alignment Length:	365	Identity:	103/365 - (28%)
Similarity:	176/365 - (48%)	Gaps:	38/365 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IKVVVR-CRPMNQTEKERNCQNIVEINEFAVSVTNP---------SARISQ--QKKFIFDSVYNM 57
            :||::| |....:...|.:....|:..:..:::.:|         ..|.||  .|.|.||:|:..
  Rat   471 VKVMLRICSASARDTSESSSFLKVDPRKKQITLYDPLTCGGHNAFQKRSSQVPPKMFAFDAVFPQ 535

  Fly    58 KTDTEVIYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERI 122
            ......:.......:::|.:.|.:|.:|.:|....||::||.|.::...:.||||.....:|:.|
  Rat   536 DASQAEVCAGTVAEVIQSVVNGADGCVFCFGHAKLGKSYTMIGRDDSMQNLGIIPCAISWLFKLI 600

  Fly   123 S---MTTNVRYLALVTYLEIY--NERIRDLLNK--------NENTNVINHFLKELPGIGVSVPTL 174
            :   ..|..|:...::.:|::  .|.:||||::        .::..|   :|.|.|..|..:...
  Rat   601 NERKEKTGARFSVRISAVEVWGKEENLRDLLSEVATGSLQDGQSPGV---YLCEDPICGTQLQNQ 662

  Fly   175 TTQPVVNANQCYDWLHFGNKNRVTAATLMNKNSSR-SHTIFTITLEQSPFLNSIGSDAFGGICRG 238
            :......|.:...:|.....:|.:.....:::..| ||.:||:.:.|.....|......||  |.
  Rat   663 SELRAPTAEKAAFFLDAAIASRRSNQQDCDEDDHRNSHMLFTLHIYQYRMEKSGKGGMSGG--RS 725

  Fly   239 KLSLVDLAGSERQRKTGAQGDRLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDS 303
            :|.|:||....:......:|     .|.:.||||||||||.:||:| :||:|:::||||.||::|
  Rat   726 RLHLIDLGSCVKALSKNREG-----GSGLCLSLSALGNVILALVNG-SKHIPYKESKLTMLLRES 784

  Fly   304 LGG-NTKTLMISCISPTDIHYDETISTLRYASRAKNISNK 342
            ||. |.:|.||:.||.....|.||:||::.|||...:..|
  Rat   785 LGNVNCRTTMIAHISAAAGSYAETLSTIQIASRVLRMKKK 824

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:277568	102/360 (28%)
Kif3C	NP_651939.4	Kinesin	10..339	CDD:278646	100/355 (28%)
Kif26b	XP_038946745.1	KISc	470..818	CDD:276812	101/357 (28%)
Kif26b	XP_038946745.1	PHA03307	1721..>2012	CDD:223039
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4280
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900