Protein Alignment Kif3C and Kif3b

DIOPT Version :9

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001099999.1
• Gene: Kif3b / 296284
• RGDID: 1306815
• Length: 747
• Species: Rattus norvegicus
• Alignment Length: 701
• Identity: 255/701 - (36%)
• Similarity: 374/701 - (53%)
• Gaps: 121/701 - (17%)

  Fly     2 SENIKVVVRCRPMNQTEKERNCQNIVEINE--FAVSVTNPSARISQQ-KKFIFDSVYNMKTDTEV 63
            ||:::|||||||||..||......:|:::.  ..|||.||.....:. |.|.||:||:.......
  Rat     7 SESVRVVVRCRPMNGKEKAAAYDKVVDVDVKLGQVSVKNPKGTSHEMPKTFTFDAVYDWNAKQFE 71

  Fly    64 IYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERISMTTNV 128
            :|||....||:|.::|:|||||||||||.|||:||:|........|:||..|||||..||.:.|.
  Rat    72 LYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGVRGDPEKRGVIPNSFDHIFTHISRSQNQ 136

  Fly   129 RYLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNANQCYDWLHFGN 193
            :||...:|||||.|.|||||:|::...:   .|||.|..||.|..|::....:..:....::.||
  Rat   137 QYLVRASYLEIYQEEIRDLLSKDQTKRL---ELKERPDTGVYVKDLSSFVTKSVKEIEHVMNVGN 198

  Fly   194 KNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAGSERQRKTGAQG 258
            :||...||.||::|||||.||.||:|.|    .:|.|....|..|||:||||||||||.||||||
  Rat   199 QNRSVGATNMNEHSSRSHAIFVITVECS----EVGLDGENHIRVGKLNLVDLAGSERQAKTGAQG 259

  Fly   259 DRLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKTLMISCISPTDIHY 323
            :|||||::|||||||||||||:|||||:.|:|:||||||||||||||||.||:|::.:.|...:.
  Rat   260 ERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNV 324

  Fly   324 DETISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYLKRML-------------------- 368
            :||::|||||:|||||.|||::|||||||.||::|.||..||..|
  Rat   325 EETLTTLRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGS 389

  Fly   369 --------QESQQIINKNNDPNKIIKSPLKIIQHTNMNSTKNVQIIDLGRNCKASFKTNNSILTK 425
                    :|.::...:.:|.:...:.     |...:...|...:.|            :|::.:
  Rat   390 GGGGEEEEEEGEEGEEEGDDKDDYWRE-----QQEKLEIEKRAIVED------------HSLVAE 437

  Fly   426 PNFPLIQSKEEVQLQARSRID-----------LIKRSLIGGERIHD--------FELKEKHMARK 471
            ....|::.||:.....|...|           :..:.|:||:.|.|        .|.|.:.:|.:
  Rat   438 EKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQ 502

  Fly   472 YAAQRHLSAIAIALSRVKCEDRD----LLQGHYATITQEIDIKNDYIRKCKEKIKMLEMEVSDLN 532
            ...:|.:        :.:.|.||    .|:..|.::.||:|||...::|...|::.::.|:.||.
  Rat   503 KRREREI--------QQQMESRDEETLELKETYTSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQ 559

  Fly   533 SEFQLDREDYLDEIRN-LGRQVKFHQQLFLKFSSNPGKFDRNWTP----DTILQNSLWNDDLKMW 592
            .|...:|:: |::.:| |.|::|....:.           .|:.|    :.|:..|.::|:...|
  Rat   560 EEHIKERQE-LEQTQNELTRELKLKHLII-----------ENFIPLEEKNKIMNRSFFDDEEDHW 612

  Fly   593 ------RIPESDLIKLP--------PATQKSGLHCIHPLVIHSENQHNNQN 629
                  |:....::|.|        |.:|    |....::|..|.::..:|
  Rat   613 KLHPITRLENQQMMKRPVSAVGYKRPLSQ----HARMSMMIRPEPRYRAEN 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:277568	177/338 (52%)
		Kinesin	10..339	CDD:278646	173/331 (52%)
Kif3b	NP_001099999.1	KISc_KIF3	8..340	CDD:276822	177/338 (52%)
		Smc	<352..>614	CDD:224117	58/298 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4280
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145782at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820