Protein Alignment Kif3C and Kif7

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001419074.1
• Gene: Kif7 / 293047
• RGDID: 1310310
• Length: 1341
• Species: Rattus norvegicus
• Alignment Length: 571
• Identity: 176/571 - (30%)
• Similarity: 271/571 - (47%)
• Gaps: 95/571 - (16%)

  Fly     5 IKVVVRCRPMNQTEKERNCQNIVEINEFAVSVTNPSARISQQKKFIFDSVYNMKTDTEVIYDEMC 69
            ::|.:|.||:...|.....|:.:::......:|     :.:.:.|.|..|.......|.:|....
  Rat    16 VRVALRVRPLLPKELLHGHQSCLQVEPERGRIT-----LGRDRHFGFHVVLGEDAGQEAVYQACV 75

  Fly    70 YSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFS----NSTGIIPKCFDHIFERISMTTNVRY 130
            ..|:|:..||:|.|:|||||||.|||:|| |:.:.:    :..||||:.....|:.|.....:..
  Rat    76 QPLLEAFFEGFNATVFAYGQTGSGKTYTM-GEASVASLHEDEQGIIPRAMAEAFKLIDENDLLDC 139

  Fly   131 LALVTYLEIYNERIRDL-----------LNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNANQ 184
            |..|:|||:|.|..|||           |.:::..||:...:||:             .|...::
  Rat   140 LVHVSYLELYKEEFRDLLEVGTASRDIQLREDDRGNVVLCGVKEV-------------DVEGLDE 191

  Fly   185 CYDWLHFGNKNRVTAATLMNKNSSRSHTIFTITLEQ---SPFLNSIGSDAFGGICRGKLSLVDLA 246
            ....|..||..|.|.||..|:.||||||:||:||||   :|  ..:.....|.:...|...||||
  Rat   192 VLSLLEMGNAARHTGATHFNRLSSRSHTVFTVTLEQRGRAP--TRLPRPGAGHLLVSKFHFVDLA 254

  Fly   247 GSERQRKTGAQGDRLKEASQINLSLSALGNVISSLVD--GKAKHVPFRDSKLTRLLQDSLGGNTK 309
            ||||..|||:.|:||||:.|||.:|.|||||||:|.|  .:..|:|:||||:||:|:||||||.|
  Rat   255 GSERVLKTGSTGERLKESIQINSTLLALGNVISALGDPQRRGSHIPYRDSKITRILKDSLGGNAK 319

  Fly   310 TLMISCISPTDIHYDETISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYLKRMLQESQQI 374
            |:||:|:||:...:|||::||.|||||:||.|:..:|..|:..|:.:               :|.
  Rat   320 TVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVNWRPEAERVPE---------------EQA 369

  Fly   375 INKNNDPNKIIKSPLKIIQHTNMNSTKNVQII----DLGRNC-------KASFKTNNSILTKPNF 428
            ......|..  :|..:||..........|...    .||..|       .|::.....:..:|..
  Rat   370 AGARGPPRH--RSETRIIHRGRRVLCPGVGSAAVAPGLGTECARCRARTSAAYSLLRELQAEPGL 432

  Fly   429 PLIQSKEEVQLQARSRIDLI-----KRSLIGGERIHDFELKEKHMARKYAAQ-----------RH 477
            |        ...||...|.:     :||.:......|..: |...|...|||           :.
  Rat   433 P--------GAAARKVRDWLCAVEGERSALSSASGPDSGI-ESAPADDQAAQGTSGRKGDEGAQQ 488

  Fly   478 LSAIAIALSRVKCEDRDLLQGHYATITQEIDIKNDYIRKCKEKIKMLEMEV 528
            |..:...::|::.|:||.|.. .....::..:::|.:|:.:|::..|.:.:
  Rat   489 LLILQSQVARLEEENRDFLAA-LEDAMEQYKLQSDRLREQQEEMVELRLRL 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	137/353 (39%)
Kif7	NP_001419074.1	KISc_KIF4	15..350	CDD:276823	138/354 (39%)
		Smc	<700..>1196	CDD:440809