Protein Alignment Kif3C and klp-11

DIOPT Version :9

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001369897.1
• Gene: klp-11 / 177685
• WormBaseID: WBGene00002222
• Length: 782
• Species: Caenorhabditis elegans
• Alignment Length: 615
• Identity: 229/615 - (37%)
• Similarity: 346/615 - (56%)
• Gaps: 58/615 - (9%)

  Fly     3 ENIKVVVRCRPMNQTEKERNCQNIVEI--NEFAVSVTNPSARISQQKKFIFDSVYNMKTDTEVIY 65
            |.:||:|||||::..|...|...||.:  ....:.:.||..:....|.|.||::|:..:....:|
 Worm    12 ETVKVIVRCRPLSSQEIANNYSKIVHMRPQRGQIELKNPKEQDEPSKDFTFDAIYDENSTQSDLY 76

  Fly    66 DEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERISMTTNVRY 130
            :|....||:|.:.|||.|||||||||.||||||:|..:.....|:|.||.|||||.::.:.|..|
 Worm    77 EETFRDLVDSVLNGYNATIFAYGQTGTGKTHTMEGKSSDPEQRGVIYKCIDHIFEHMAASHNQEY 141

  Fly   131 LALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNANQCYDWLHFGNKN 195
            |...:|||||.|.:||||....|..:   .:||.|..||.|..||::......:.::.:..||.:
 Worm   142 LVRASYLEIYQEELRDLLEAESNKKL---EIKERPDGGVYVKDLTSKLTRTVGEIHEVMIRGNGH 203

  Fly   196 RVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAGSERQRKTGAQGDR 260
            |....|.||::|||||.||.||:|.|    .||.|....|..|:|:||||||||||.||||.|:|
 Worm   204 RSVGRTNMNEHSSRSHAIFIITVECS----RIGEDGESHITVGRLNLVDLAGSERQSKTGATGER 264

  Fly   261 LKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKTLMISCISPTDIHYDE 325
            .|||::|||||||||||||:|||.|:.|:|:||||||||||||||||:||:|::||.|...:::|
 Worm   265 FKEATKINLSLSALGNVISALVDAKSAHIPYRDSKLTRLLQDSLGGNSKTVMVACIGPASYNFEE 329

  Fly   326 TISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYLKRMLQE---------SQQIIN----K 377
            |:.|||||:|||||.|:||||||||||.||::|.||..|:..|::         :|...:    |
 Worm   330 TLGTLRYANRAKNIKNQPKINEDPKDALLREFQEEIEMLREQLKQRKTRSRDGATQSFYDAERAK 394

  Fly   378 NNDPNKIIKSPLKIIQHTNMNSTKNVQ----IIDLGRNCKASFKTNNSILTKPNFPLIQSKEEVQ 438
            ..|..:.|:....:|:|......:.:|    :::..|..:|  :....|....:..::.|:|:.:
 Worm   395 LEDDIEAIQKDDSLIKHEKDRLIREIQEKHDLLEKERIEQA--RVAERIANIQSRLIVGSEEDGR 457

  Fly   439 LQARSRIDLIKRSLIGGERIHDFELKEKHMARKYAAQRHLSAIAIALSRVKCEDRDLLQGHYATI 503
            |::|::           |:....|.|.:.:|.:...:|.:   ..||.|.:.:..||.| .::.:
 Worm   458 LESRTK-----------EQHAQLEKKRRELAEQKRREREM---VEALERQEEDTVDLKQ-TFSDL 507

  Fly   504 TQEIDIKNDYIRKCKEKIKMLEMEVSDLNSEFQLDREDYLDEIRNLGRQVKFHQQLFLKFSSNPG 568
            ..|::.|...::|...|::....|:.|::..:..:|:|....|..:.:::|....:.
 Worm   508 RTEVEAKTKKLKKMLIKLRQARNEIRDVSGAYSDERQDLDQTIAEVSKELKLKLLIV-------- 564

  Fly   569 KFDRNWTP----DTILQNSLWNDDLKMWRI 594
               .|:.|    :.|.:.:.||:|...|.:
 Worm   565 ---ENFIPRDVSERIKERAEWNEDSFEWNV 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:277568	167/337 (50%)
		Kinesin	10..339	CDD:278646	163/330 (49%)
klp-11	NP_001369897.1	Motor_domain	12..343	CDD:419868	167/337 (50%)
		SMC_prok_B	337..>584	CDD:274008	63/274 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145782at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920