Protein Alignment Kif3C and osm-3

DIOPT Version :9

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001367796.1
• Gene: osm-3 / 177141
• WormBaseID: WBGene00003884
• Length: 699
• Species: Caenorhabditis elegans
• Alignment Length: 641
• Identity: 278/641 - (43%)
• Similarity: 376/641 - (58%)
• Gaps: 62/641 - (9%)

  Fly     1 MSENIKVVVRCRPMNQTEKERNCQNIVEINEFAVSVTNPSARISQQKKFIFDSVYNMKTDTEVIY 65
            |:|:::|.|||||.||.||:.|....|.:.. .|...|.:|.....|.|.||..|.|.:..|.||
 Worm     1 MAESVRVAVRCRPFNQREKDLNTTLCVGMTP-NVGQVNLNAPDGAAKDFTFDGAYFMDSTGEQIY 64

  Fly    66 DEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERISMTTNVRY 130
            :::.:.|||:.|||||||:|||||||.|||.:|||.|......|:||:.|||||...:.|.||::
 Worm    65 NDIVFPLVENVIEGYNGTVFAYGQTGSGKTFSMQGIETIPAQRGVIPRAFDHIFTATATTENVKF 129

  Fly   131 LALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNANQCYDWLHFGNKN 195
            |...:|||||||.:||||..:....:   .:||.|..||.|..|:.....:...|.:.:..|..|
 Worm   130 LVHCSYLEIYNEEVRDLLGADNKQKL---EIKEQPDRGVYVAGLSMHVCHDVPACKELMTRGFNN 191

  Fly   196 RVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAGSERQRKTGAQGDR 260
            |...||||||:|||||:|||:.:|        |....|.|..|||:||||||||||.||||.|||
 Worm   192 RHVGATLMNKDSSRSHSIFTVYVE--------GMTETGSIRMGKLNLVDLAGSERQSKTGATGDR 248

  Fly   261 LKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKTLMISCISPTDIHYDE 325
            ||||::|||||||||||||:|||||:||:|:|||||||||||||||||||:||:|:||:..:|||
 Worm   249 LKEATKINLSLSALGNVISALVDGKSKHIPYRDSKLTRLLQDSLGGNTKTIMIACVSPSSDNYDE 313

  Fly   326 TISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYLKRMLQ--------ESQQIINKNNDPN 382
            |:||||||:|||||.|||.||||||||.||:||.||..||.|:|        .:|...:...:..
 Worm   314 TLSTLRYANRAKNIKNKPTINEDPKDALLREYQEEIARLKSMVQPGAVGVGAPAQDAFSIEEERK 378

  Fly   383 KI----------IKSPLKIIQHTNMNSTKNVQIIDLGRNCKASFKTNNSILTKPNFPLIQSKEEV 437
            |:          ::...:..|.:.....|:::      :.:|.::..|:.|...|      .||
 Worm   379 KLREEFEEAMNDLRGEYEREQTSKAELQKDLE------SLRADYERANANLDNLN------PEE- 430

  Fly   438 QLQARSRIDLIKRSLIGGERIHDFELKEKHMARKYAAQRHLSAIAIALSRVKCEDRDLLQGHYAT 502
               |..:|..::...||||...:.:||:|.|.:...|:.....:|.||:..|  |..||| .|:|
 Worm   431 ---AAKKIQQLQDQFIGGEEAGNTQLKQKRMKQLKEAETKTQKLAAALNVHK--DDPLLQ-VYST 489

  Fly   503 ITQEIDIKNDYIRKCKEKIKMLEMEVSDLNSEFQLDREDYLDEIRNLGRQVKFHQQLFLKFSSNP 567
            ..:::|.....:.|..:|.|..|.|:.||:.||:|||.||||.||...:|:|...|:..|.....
 Worm   490 TQEKLDAVTSQLEKEVKKSKGYEREIEDLHGEFELDRLDYLDTIRKQDQQLKLLMQIMDKIQPII 554

  Fly   568 GKFDRNWT-PDTILQNSLWNDDLKMWRIPESDLIK--LP---------PATQKSGL 611
            .| |.|:: .|.|.:.::||:|...|.:||..:.:  ||         ||.|::.|
 Worm   555 KK-DTNYSNVDRIKKEAVWNEDESRWILPEMSMSRTILPLANNGYMQEPARQENTL 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:277568	183/335 (55%)
		Kinesin	10..339	CDD:278646	180/328 (55%)
osm-3	NP_001367796.1	Motor_domain	3..327	CDD:419868	183/335 (55%)
		SMC_prok_B	<342..559	CDD:274008	66/236 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158540
Domainoid	1	1.000	106	1.000	Domainoid score	I4116
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5883
Inparanoid	1	1.050	445	1.000	Inparanoid score	I917
Isobase	1	0.950	-	0	Normalized mean entropy	S2602
OMA	1	1.010	-	-		QHG29098
OrthoDB	1	1.010	-	-		D145782at33208
OrthoFinder	1	1.000	-	-		FOG0006941
OrthoInspector	1	1.000	-	-		oto18152
orthoMCL	1	0.900	-	-		OOG6_107365
Panther	1	1.100	-	-	LDO	PTHR24115
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2703
SonicParanoid	1	1.000	-	-		X5033
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.890