Protein Alignment Kif3C and klp-19

DIOPT Version :9

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_499742.1
• Gene: klp-19 / 176750
• WormBaseID: WBGene00002229
• Length: 1083
• Species: Caenorhabditis elegans
• Alignment Length: 573
• Identity: 177/573 - (30%)
• Similarity: 278/573 - (48%)
• Gaps: 91/573 - (15%)

  Fly     4 NIKVVVRCRPMNQTEKERNCQNIVEINEFAVSVTNPSARISQQKKFIFDSVYNMKTDTEVIYDEM 68
            :::||||.||||..|.:......|:..|....:.     |::...|.||:|:...:|.|.:|:..
 Worm     6 SLRVVVRARPMNGRETKEGASRCVQFYENTKQIV-----INESATFTFDAVFADTSDQESVYETT 65

  Fly    69 CYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNS---TGIIPKCFDHIFERISMTTNVRY 130
            ...|::....|:|.|:.||||||.|||:||..::|....   .||||:....:|:||..|.....
 Worm    66 ALPLLDRIFAGFNATVLAYGQTGSGKTYTMGTEDNVGTDEMRRGIIPRLVSALFQRIMNTEAPES 130

  Fly   131 LAL-VTYLEIYNERIRDLLNKN----------ENTNVINHFLKELPGIGVSVPTLTTQPVVNANQ 184
            .|: |:..|:|.:.:.|||..:          :|..|:|               ||..||::...
 Worm   131 FAVTVSMFEVYGDNVYDLLRPDKVKLNVHGDEKNCTVVN---------------LTAVPVIDLKG 180

  Fly   185 CYDWLHFGNKNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAGSE 249
            ....|..|...|..|.|.||..|||||.:||:.:|::.....  ..||.    .||.||||||||
 Worm   181 ALKQLAVGCHYRTKAETAMNAMSSRSHAVFTVFVEKTATAEC--DSAFS----AKLQLVDLAGSE 239

  Fly   250 RQRKTGAQGDRLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKTLMIS 314
            |.:||.|:|:|:||...||..|..|..||::|.. |.||:|:|:|.:||:||||||||:.|:.::
 Worm   240 RLKKTEAEGNRMKEGININGGLLILSQVIAALAT-KQKHIPYRNSVITRVLQDSLGGNSFTVFLA 303

  Fly   315 CISPTDIHYDETISTLRYASRAKNISNKPKINEDPK-------DARLRQYQNEILYLKRMLQESQ 372
            ||||.|.:..||::|||||.|||.|.|||.:|::||       .|:|::.|.|...||:.:..::
 Worm   304 CISPADSNSQETLNTLRYADRAKQIKNKPIVNKNPKAEEIAILQAQLKRLQKENADLKQGIAPAE 368

  Fly   373 QIINKNNDPNKIIKSPLKIIQHTNM---NSTKNVQIIDLGRNCKASFKTNNSILTKPNFPLIQSK 434
            ...|..|:..:|:....::::.|..   .:.|..:.|           ...|.||:.|..|.:.|
 Worm   369 VRFNDANNSAEILSLKEEVVRKTEQLKERAMKQSECI-----------IRMSALTQKNSRLEEDK 422

  Fly   435 EEVQLQARSRIDLIKRSLIGGERIHDFELKEKHMARKYAAQRHLSAIAIALSRVKCEDRD--LLQ 497
            .::|    |.:..::.:::..|.:...|: .:.:.:........:.:|       .:|.|  .|.
 Worm   423 AKLQ----SMLTDVRNTVLNEEMLDAAEV-VRSIQQVVGDTEESTTLA-------DDDNDETALG 475

  Fly   498 GHYATITQEIDIKNDYIRKCKEKIKMLEMEVSDLNSEFQL---DREDYLDEIR 547
            |...||..            .|::..|:.|:.||..:..:   :|:..|||.|
 Worm   476 GQDDTIYD------------TERLPELQAELDDLEKQIAMKDENRQKALDEQR 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:277568	131/348 (38%)
		Kinesin	10..339	CDD:278646	128/342 (37%)
klp-19	NP_499742.1	KISc	6..326	CDD:276812	129/346 (37%)
		SMC_prok_A	<342..621	CDD:274009	39/210 (19%)
		Smc	<481..825	CDD:224117	11/48 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910