Protein Alignment Kif3C and unc-116

DIOPT Version :9

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001370811.1
• Gene: unc-116 / 176179
• WormBaseID: WBGene00006840
• Length: 815
• Species: Caenorhabditis elegans
• Alignment Length: 639
• Identity: 200/639 - (31%)
• Similarity: 315/639 - (49%)
• Gaps: 105/639 - (16%)

  Fly     5 IKVVVRCRPMNQTEKERNCQNIVE--INEFAVSVTNPSARISQQKKFIFDSVYNMKTDTEVIYDE 67
            ::|..|.||:|:|| |:|....:.  .:|.::|:..        |.::||.|:...|..|.:|..
 Worm    12 VQVFCRIRPLNKTE-EKNADRFLPKFPSEDSISLGG--------KVYVFDKVFKPNTTQEQVYKG 67

  Fly    68 MCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERI-SMTTNVRYL 131
            ..|.:|:..:.|||||:||||||..||||||:|....:..:||||:....||..| ||..|:::.
 Worm    68 AAYHIVQDVLSGYNGTVFAYGQTSSGKTHTMEGVIGDNGLSGIIPRIVADIFNHIYSMDENLQFH 132

  Fly   132 ALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTL---TTQPVVNANQCYDWLHFGN 193
            ..|:|.|||||:|||||:. |..|:..|..|.      .||.:   |.:.|...::....:..|.
 Worm   133 IKVSYYEIYNEKIRDLLDP-EKVNLSIHEDKN------RVPYVKGATERFVGGPDEVLQAIEDGK 190

  Fly   194 KNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAGSERQRKTGAQG 258
            .||:.|.|.||::|||||::|.||::|.       .........|||.||||||||:..||||||
 Worm   191 SNRMVAVTNMNEHSSRSHSVFLITVKQE-------HQTTKKQLTGKLYLVDLAGSEKVSKTGAQG 248

  Fly   259 DRLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKTLMISCISPTDIHY 323
            ..|:||..||.||:|||.|||:|.:|...|||:|||||||:||:|||||::|.:|.|.||:..:.
 Worm   249 TVLEEAKNINKSLTALGIVISALAEGTKSHVPYRDSKLTRILQESLGGNSRTTVIICASPSHFNE 313

  Fly   324 DETISTLRYASRAKNISNKPKINED-PKDARLRQYQNE---ILYLKRMLQESQQIINKNNDPNKI 384
            .||.|||.:.:|||.|.|..:|||: ..:...|:|:.|   ...|..:||.:...:::......:
 Worm   314 AETKSTLLFGARAKTIKNVVQINEELTAEEWKRRYEKEKEKNTRLAALLQAAALELSRWRAGESV 378

  Fly   385 IKSPLKIIQHTNMNSTKNVQIIDLGRN----CKASFKTNNSILTKPNFPLIQSK----EEVQLQA 441
            .:     ::..|::.:..:.:.::...    .:.|......:||....|:...:    ||.:::.
 Worm   379 SE-----VEWVNLSDSAQMAVSEVSGGSTPLMERSIAPAPPMLTSTTGPITDEEKKKYEEERVKL 438

  Fly   442 RSRID--------------------LIKRSLIGGERIHDFEL--KEKHMARKYAAQRH------- 477
            ..::|                    |::...:|..|.:: ||  :|.:..:|.|..:.
 Worm   439 YQQLDEKDDEIQKVSQELEKLRQQVLLQEEALGTMRENE-ELIREENNRFQKEAEDKQQEGKEMM 502

  Fly   478 --LSAIAIALS--RVKC-----------EDRDLLQGHYATITQEIDIKNDYIRKCKEKIK----- 522
              |..||:.|.  :.:|           ||...|:..   :.|...:.|.::.:|..||:
 Worm   503 TALEEIAVNLDVRQAECEKLKRELEVVQEDNQSLEDR---MNQATSLLNAHLDECGPKIRHFKEG 564

  Fly   523 ----MLEMEVSDLNSE-FQLDREDYLDEIRNLGRQVKFHQQLFLKFSSNPGKFD 571
                :.|..::|:.|: .||...|.|:.:| :|....|.:....|.||...:.|
 Worm   565 IYNVIREFNIADIASQNDQLPDHDLLNHVR-IGVSKLFSEYSAAKESSTAAEHD 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:277568	146/339 (43%)
		Kinesin	10..339	CDD:278646	145/334 (43%)
unc-116	NP_001370811.1	KISc_KHC_KIF5	9..329	CDD:276820	146/339 (43%)
		SMC_prok_A	440..>782	CDD:274009	36/183 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910