Protein Alignment Kif3C and Kifc2

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001403226.1
• Gene: Kifc2 / 16581
• MGIID: 109187
• Length: 805
• Species: Mus musculus
• Alignment Length: 353
• Identity: 125/353 - (35%)
• Similarity: 178/353 - (50%)
• Gaps: 38/353 - (10%)

  Fly     4 NIKVVVRCRPMNQTEKERNCQNIVEINEFAVSVTNPSARISQQKKFIFDSVYNMKTDTEVIYDEM 68
            ||:|:.|.||     .|....::|.: |.....|..:....:|.:|..|.|:......|.::.::
Mouse   422 NIRVLCRLRP-----AEGQPSSLVSV-EPGQGGTITTCYRGRQHRFRLDWVFPQDASQEEVFRQL 480

  Fly    69 CYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERISMTTNVRYLAL 133
             ...|.|.::||:..||.|||||.|||::|:|.   ....||.|:....:|.  .|.|...:...
Mouse   481 -EPAVLSCLQGYSVCIFTYGQTGTGKTYSMEGP---PEDPGIAPRALQLLFR--EMGTGGHHHVT 539

  Fly   134 VTYLEIYNERIRDLLNKNENTNVINHFLKELPG--IGVSVPTLTTQPVVNANQCYDWLHFGNKNR 196
            ::.:|||||.:||||.......::   :::.|.  .|:.|..||...|.|....:..|..|..||
Mouse   540 LSMVEIYNEAVRDLLATGPPERLV---VRQGPAGQGGIQVAGLTHWDVPNLETLHQMLSLGRSNR 601

  Fly   197 VTAATLMNKNSSRSHTIFTITLEQS--PFLNSIGSDAFGGICRGKLSLVDLAGSERQRKTG---- 255
            .||||:||::|||||.:.|:||..:  |....|         .|.|.|||||||||..|.|
Mouse   602 ATAATVMNQHSSRSHALVTLTLRAASPPRAQGI---------TGTLHLVDLAGSERVWKAGVASP 657

  Fly   256 AQGD-----RLKEASQINLSLSALGNVISSLVDGKAKHVPFRDSKLTRLLQDSLGGNTKTLMISC 315
            .|.|     ||:||..||.||.|||.|:::| ..:..|||||||:||||||.:|...|..:::..
Mouse   658 VQRDPNGARRLREAQAINRSLLALGGVMAAL-RARRPHVPFRDSQLTRLLQPALCAGTTAVLLLQ 721

  Fly   316 ISPTDIHYDETISTLRYASRAKNISNKP 343
            ||.......|||.:|::|.|...:...|
Mouse   722 ISTRAEDLGETICSLKFAERVGQVELGP 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	124/347 (36%)
Kifc2	NP_001403226.1	Smc	<270..>345	CDD:440809
		Motor_domain	421..747	CDD:473979	124/349 (36%)