Protein Alignment Kif3C and Kifc5b

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_444403.2
• Gene: Kifc5b / 16580
• MGIID: 2137414
• Length: 672
• Species: Mus musculus
• Alignment Length: 372
• Identity: 132/372 - (35%)
• Similarity: 187/372 - (50%)
• Gaps: 62/372 - (16%)

  Fly     4 NIKVVVRCRPMNQTEKERNCQNIVEINEFAVSVTNPSAR-----ISQ----------------QK 47
            ||:|..|.||:.:.|...:...:|    |......||.|     :|:                :.
Mouse   309 NIRVFCRVRPVLEGESTPSPGFLV----FPPGPAGPSDRPTGLSLSRSDDRRSTLTGAPAPTVRH 369

  Fly    48 KFIFDSVYNMKTDTEVIYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQ----GDENFSNST 108
            .|.||.|:...:..|.:::|:. .||:|.::||...||||||||.|||.||:    ||...:
Mouse   370 DFSFDRVFPPGSKQEEVFEEIA-MLVQSALDGYPVCIFAYGQTGSGKTFTMEGGPRGDPQLA--- 430

  Fly   109 GIIPKCFDHIFERISMTTNV-----RYLALVTYLEIYNERIRDLL----NKNENTNVINHFLKEL 164
            |:||:...|:|   |:...:     .|..:.:|:|||||.:||||    .|.:....  ...:..
Mouse   431 GLIPRAMRHLF---SVAQEMSGQGWTYSFVASYVEIYNETVRDLLATGPRKGQGGEC--EIRRAS 490

  Fly   165 PGI-GVSVPTLTTQPVVNANQCYDWLHFGNKNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIG 228
            ||. .::|......||....:....||..::||..|.|..||.|||||::|.:.:.        |
Mouse   491 PGSEELTVTNARYVPVSCEKEVEALLHLAHQNRAVAHTAQNKRSSRSHSVFQLQIS--------G 547

  Fly   229 SDAFGGI-CRGKLSLVDLAGSERQRKTGAQG----DRLKEASQINLSLSALGNVISSLVDGKAKH 288
            ..|..|: |...|:|||||||||.......|    |||:|...||.|||.||.||.:| ..|..|
Mouse   548 EHAARGLQCGAPLNLVDLAGSERLDPGLPLGPGERDRLRETQAINSSLSTLGLVIMAL-SNKESH 611

  Fly   289 VPFRDSKLTRLLQDSLGGNTKTLMISCISPTDIHYDETISTLRYASR 335
            ||:|:||||.|||:||||:.|.||...|||.:.:..|::::||:||:
Mouse   612 VPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASK 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	132/372 (35%)
Kifc5b	NP_444403.2	SMC_prok_B	<144..306	CDD:274008
		KISc_C_terminal	307..664	CDD:276817	132/372 (35%)