Protein Alignment Kif3C and Kif9

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001398108.1
• Gene: Kif9 / 16578
• MGIID: 1098237
• Length: 824
• Species: Mus musculus
• Alignment Length: 737
• Identity: 195/737 - (26%)
• Similarity: 294/737 - (39%)
• Gaps: 231/737 - (31%)

  Fly     3 ENIKVVVRCRPMNQTEKERNCQNIVEINEFAVSVTNPSARISQQKKFIFDSVYNMKTD------- 60
            :.::..||.||.:....|     :::..|     .|.|..|..:|......|.|.:||
Mouse    19 KKVQAFVRVRPTDDFAHE-----MIKYGE-----DNKSIDIHLKKDTRRGVVNNQQTDWSFKLDG 73

  Fly    61 ------TEVIYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQG-DENFSNSTGIIPKCFDHI 118
                  .:::|:.:....|...::||||||..|||||.|||:||.| .||:.: .||:|:....:
Mouse    74 VLHNASQDLVYETVAKDAVSQALDGYNGTIMCYGQTGAGKTYTMTGATENYKH-RGILPRALQQV 137

  Fly   119 FERISMTTNVRYLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVNAN 183
            |..|...........|:|||||||.:.|||:             .||.:|   |::|...:|...
Mouse   138 FRMIEERPTHAITVRVSYLEIYNENLFDLLS-------------TLPYVG---PSVTPMTIVENP 186

  Fly   184 Q-----------------CYDWLHFGNKNRVTAATLMNKNSSRSHTIFTI-------TLEQSPFL 224
            |                 .:..|..|..||:.|:..|||||||||.||||       ||....::
Mouse   187 QGIFIKGLSVHLTSQEEDAFSLLFEGETNRIIASHTMNKNSSRSHCIFTIYMEAHSRTLSDEKYI 251

  Fly   225 NSIGSDAFGGICRGKLSLVDLAGSERQRKTGAQGDRLKEASQINLSLSALGNVISSLVDGKAKHV 289
            .|            |::|||||||||..|||::|..||||:.||.|||.|...|.:|.|....||
Mouse   252 TS------------KINLVDLAGSERLSKTGSEGRVLKEATYINKSLSFLEQAIIALGDQNRDHV 304

  Fly   290 PFRDSKLTRLLQDSLGGNTKTLMISCISPTDIHYDETISTLRYASRAKNISNKPKINEDPKDARL 354
            |||.||||..|:||||||...::::.|.......|||:|:||:|||.|.::.:|.|||.....|:
Mouse   305 PFRQSKLTHALKDSLGGNCNMVLVTNIYGEAAQLDETLSSLRFASRMKLVTTEPAINEKYDAERM 369

  Fly   355 -RQYQNEILYLKRMLQESQQIINK---NNDPNKIIKSPLKIIQHTNMNS---------TKNVQII 406
             :..:.|:..||:.|.....:.|:   |.|       |:..||...:||         ...:.||
Mouse   370 VKNLEKELALLKQELAIHDSLSNRTLVNYD-------PMDEIQIAEINSQVRRYLEGTLDEIDII 427

  Fly   407 DLGRNCKASFKTNNSILT----------KPNFPLIQSKEEVQLQARSRIDL--IKRSLIG----- 454
            :| |..:..|.....:|:          :..:.||...:...:.|..::.|  |:.:|:|
Mouse   428 NL-RQIQEVFNQFRVVLSQQEQEVESALRRKYTLIDKNDFAAISAVQKVGLMDIEGNLVGEPDGQ 491

  Fly   455 --GERIHDFELKE--------------KHMARK-------------------------------- 471
              |..:..|.:|.              ...|||
Mouse   492 SFGLGVAPFSVKPGKKPKTKKTPKDQFSSSARKEGASSPVSGKDFDVASISKTQLIPSSKDGDLK 556

  Fly   472 --YAAQRHLSAIAIALS----------------------------------RVKCEDRDLLQ--- 497
              .|.:|..|:|...:|                                  |:..|::.:|.
Mouse   557 DMLARERETSSIEPLISDSPKEELRAPRPSTPPSRTVAFEEFKNERGSEINRIFKENKSILNERK 621

  Fly   498 -------GHYATITQEIDIKNDYIRKCK------------------EKIKMLEMEVSDLNSEFQL 537
                   .....|.||||...|.:...|                  |:..:|.:::.||..::
Mouse   622 KRASETTQRINAIKQEIDETKDALNFQKSLREKQGEYENKGLMIIDEEEFLLILKLKDLKKQY-- 684

  Fly   538 DREDYLDEIRNLGRQVKFHQQL 559
             |.:| .|:|:|..::::.|:|
Mouse   685 -RNEY-QELRDLRAEIQYCQRL 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	133/373 (36%)
Kif9	NP_001398108.1	KISc_KIF9_like	20..352	CDD:276826	132/370 (36%)