Protein Alignment Kif3C and Kif13b

DIOPT Version :10

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_006518682.1
• Gene: Kif13b / 16554
• MGIID: 1098265
• Length: 1847
• Species: Mus musculus
• Alignment Length: 797
• Identity: 228/797 - (28%)
• Similarity: 340/797 - (42%)
• Gaps: 229/797 - (28%)

  Fly     5 IKVVVRCRPMNQTEKERNCQNIVEINEFAVSVTNP--------SARISQQKKFIFD--------S 53
            :||.||.||||:.|.:.:.:.:|::....| :.||        .|| .|.|.|.:|        |
Mouse     6 VKVAVRVRPMNRREIDLHTKCVVDVEANKV-ILNPVNTNLSKGDAR-GQPKIFAYDHCFWSMDES 68

  Fly    54 VYNMKTDTEVIYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHI 118
            |.......|.::..:..:::::..:|||..||||||||.||::||.|.   ::..|:||:....:
Mouse    69 VREKYAGQEDVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGT---ADQPGLIPRLCSGL 130

  Fly   119 FERISMTTNVR--YLALVTYLEIYNERIRDLLNKNENTNVINHFLKELPGIGVSVPTLTTQPVVN 181
            |||.....|..  :...|:|:|||||::||||:...:...:.  ::|...:|..|..|:...|.:
Mouse   131 FERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLK--VREHSVLGPYVDGLSKLAVTS 193

  Fly   182 ANQCYDWLHFGNKNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLA 246
            .......:..|||:|..|||.||:.|||||.:|.|||..:.:....|:   .|...|||||||||
Mouse   194 YKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSGT---SGEKVGKLSLVDLA 255

  Fly   247 GSERQRKTGAQGDRLKEASQINLSLSALGNVISSLVD-----GKAKHVPFRDSKLTRLLQDSLGG 306
            ||||..||||.||||||.|.||.||:.||.|||:|.|     .|.|.||:|||.||.||:|||||
Mouse   256 GSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQGAGKNKNKFVPYRDSVLTWLLKDSLGG 320

  Fly   307 NTKTLMISCISPTDIHYDETISTLRYASRAKNISNKPKINEDPKDARLRQYQNEILYLKRML--- 368
            |:||.|::.:||...:||||:||||||.|||:|.|...:||||....:|..:.|:..|:..|
Mouse   321 NSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQLTKA 385

  Fly   369 -------------------------------------QESQQ----------------------I 374
                                                 ||.|:                      :
Mouse   386 EAMKSPELKDRLEESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQTSGIKVGDDKCFL 450

  Fly   375 INKNNDP--NKIIKSPLKIIQHTNMNS--TKNVQIIDLG---------------------RNCK- 413
            :|.|.||  |:::...||  :||.:.|  ::::|:..:|                     :|.:
Mouse   451 VNLNADPALNELLVYYLK--EHTLIGSANSQDIQLCGMGILPEHGIIDITPEGQVVLTPQKNTRT 513

  Fly   414 ----------------------------------------------ASFKTNNS----------- 421
                                                          ||.|.::|
Mouse   514 FVNGSSVSSPIQLHHGDRILWGNNHFFRLNLPKKKKKAEREDEDREASLKNDSSSEQLDADGDSS 578

  Fly   422 --ILTKPNFPLIQSKEEVQLQARSRIDLIKRSLIGGERIHDFELKEKHMARKYAAQRHLSAIAIA 484
              :.::.||....::.||.::|....|.::..|...|:.|:.|.:.....::...:..|..:...
Mouse   579 SEVSSEINFNFEYAQMEVTMKALGSNDPMQSILSSLEQQHEEEKRSALERQRLMYEHELEQLRRR 643

  Fly   485 LS--RVKCEDRDLLQGHYATITQ---------EIDIKNDYIRKCKEKIK--MLEMEVSDLNSEFQ 536
            ||  |..|...|.|..|..:..|         |..:.|..:|..::.:|  :|..|.|.:..|
Mouse   644 LSPERQNCRGVDRLSFHSPSAQQRLKQWAEEREATLNNSLMRLREQIVKANLLVREASYIAEE-- 706

  Fly   537 LD-REDY----------LDEIRNLGR-------QVKFHQQLFLKFSSNPGKFDRNWTPDTILQNS 583
            || |.:|          ||..|..|.       ||:           ..||..:.|:.:. |:|.
Mouse   707 LDKRTEYKVTLQIPTSSLDANRKRGSLLSEPAIQVR-----------RKGKGKQIWSLEK-LENR 759

  Fly   584 L--WNDDLKMWRIPESD 598
            |  ..|..:.|:..|.|
Mouse   760 LLDMRDLYQEWKECEED 776

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:473979	151/356 (42%)
Kif13b	XP_006518682.1	KISc_KIF1A_KIF1B	4..360	CDD:276816	153/363 (42%)
		Kinesin_assoc	357..469	CDD:465047	18/113 (16%)
		FHA_KIF13B	447..545	CDD:438782	13/99 (13%)
		KIF1B	756..802	CDD:463574	7/21 (33%)
		C2-C2_1	<888..>952	CDD:463310
		bMERB_dom	<1073..1143	CDD:463467
		DUF3694	<1220..1277	CDD:463599
		PHA03247	<1423..1659	CDD:223021
		CAP_GLY	1724..1787	CDD:460154