Protein Alignment Kif3C and Kif19b

DIOPT Version :9

• Sequence 1: NP_651939.4
• Gene: Kif3C / 43820
• FlyBaseID: FBgn0039925
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001365608.1
• Gene: Kif19b / 101055939
• MGIID: 3646257
• Length: 974
• Species: Mus musculus
• Alignment Length: 709
• Identity: 201/709 - (28%)
• Similarity: 321/709 - (45%)
• Gaps: 153/709 - (21%)

  Fly     3 ENIKVVVRCRPMNQTEKERNCQNIV-EINEFAVSVTNPS--------ARISQQKKFIFDSVYNMK 58
            :.:.|.:|.||:|.||.|.....|. ::.:..|.:.:|.        |..|:::.||||:|::..
Mouse    26 QQLMVALRIRPLNSTELEEGATVIAHKVGDQVVVLMDPGEDPEDTLRAHRSRERTFIFDTVFDQH 90

  Fly    59 TDTEVIYDEMCYSLVESTIEGYNGTIFAYGQTGCGKTHTMQGDENFSNSTGIIPKCFDHIFERIS 123
            ...|.:|......|||..|.|||.||||||.:|.||||||.|   .....||..:....:|:.|.
Mouse    91 ASQETVYCATIQHLVEGVISGYNTTIFAYGPSGAGKTHTMLG---VDAEPGIYLQTLTDLFQAIE 152

  Fly   124 MT-TNVRYLALVTYLEIYNERIRDLLNKNENTNVINHF--LKELPGIGVSVPTLTTQPVVNANQC 185
            .| .|:.|...::|||||||.||||||.:..      |  |:|.....:.:..:|.....||.:.
Mouse   153 ETQDNMEYSVSMSYLEIYNEVIRDLLNPSSG------FLELREDSRGSIQIAGITEVSTSNAQEI 211

  Fly   186 YDWLHFGNKNRVTAATLMNKNSSRSHTIFTITLEQSPFLNSIGSDAFGGICRGKLSLVDLAGSER 250
            ...|..||:.|....|..||.|||||.:..:|:.|    .|.|.|....:..|:|.:||||||||
Mouse   212 MQLLTKGNRQRTQEPTATNKTSSRSHAVLQVTVHQ----RSRGGDLAEEVRLGRLFMVDLAGSER 272

  Fly   251 QRKTGAQGDRLKEASQINLSLSALGNVISSLVD---GKAKHVPFRDSKLTRLLQDSLGGNTKTLM 312
            ..:|..:|.|:||.:.||.||.||||.|::|.:   .:|::|.||||||||||:|:||||::|:|
Mouse   273 AAQTQNRGKRMKEGAHINRSLLALGNCINALSEKGGSRAQYVNFRDSKLTRLLKDALGGNSRTVM 337

  Fly   313 ISCISPTDIHYDETISTLRYASRAKNISNKPKINEDPKDARLRQY-------QNEILYLKRMLQE 370
            |:.|||....::|:.:||.||.|||||..:.|.|......|:.||       :.||.:||..:::
Mouse   338 IAHISPASTSFEESRTTLLYAYRAKNIKTRVKRNLLNVSYRIAQYTDVISDLRREIGHLKSKIEK 402

  Fly   371 SQQIINKNNDP---------------------NKI-------------IKSPLKIIQHTNMNSTK 401
            ..:  .|.:||                     |:|             ::..|..:::||:...
Mouse   403 QDK--EKKSDPGVLDIQVTIPHDAEEDSRLQMNRIRAQLIGAFKEQMEMRRSLVELENTNIELH- 464

  Fly   402 NVQIIDLGRNCKASFKTNNSILTKPNFPLIQSKEEVQLQARSR----IDLIKRSLIGGERIHDFE 462
                ||:.|:          :||..::...::.:.|.:.:..|    :|      ..||.:...|
Mouse   465 ----IDMSRH----------LLTIADWEREKTHQHVDVDSGERDKEPVD------ADGEEVGASE 509

  Fly   463 LKEKHMARK-----YAAQRHLSAI------AIALSRVKCEDRDLLQGHYATITQEIDIKNDYIRK 516
            ..|..:||:     .|.|:..:|:      .:|.::.|....:.|.....|..::.::.....|.
Mouse   510 PPEVALAREEVNLLLAEQQKTAALKAGLEQRLAHAKQKASQMEKLLPRQVTSEEQREVLQLLCRA 574

  Fly   517 CKEKIKMLEMEVSDLNSEFQLDREDYLDEIRNLGRQVKFHQ------------------------ 557
            .:.:::..|::..:|..:..|.::|::.:        ::||
Mouse   575 HELEVENTELQADNLFRKNLLCQKDFVIQ--------RYHQHRLLCEQVIQGQRQLMQDNGISAP 631

  Fly   558 ----QLFLKFSS--NPGKFDRNWTPDTILQNSLWNDDLKMWRIPESDLIKLPPATQKSG 610
                |.:..:|.  ..|..||     .:||.|:.:..|:...|..   :..||..:.||
Mouse   632 EPLEQQYRLYSRELGEGTLDR-----LLLQLSVMSSSLQDGPIMN---VSPPPTEESSG 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3C	NP_651939.4	Motor_domain	3..339	CDD:277568	140/350 (40%)
		Kinesin	10..339	CDD:278646	139/343 (41%)
Kif19b	NP_001365608.1	KISc_KIP3_like	27..364	CDD:276821	140/349 (40%)
		PHA03307	675..>974	CDD:223039	4/8 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910