DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pho and PZF1

DIOPT Version :9

Sequence 1:	NP_524630.1	Gene:	pho / 43819	FlyBaseID:	FBgn0002521	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_015512.1	Gene:	PZF1 / 856316	SGDID:	S000006390	Length:	429	Species:	Saccharomyces cerevisiae

Alignment Length:	196	Identity:	59/196 - (30%)
Similarity:	94/196 - (47%)	Gaps:	32/196 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   325 ISQSTHQDNTDSTGCGEMNLSEVTVSYTN-DKKIACPHKGCNKHFRDSSAMRKH-LHTH-GPRVH 386
            ||:|...::.:|       |:....|.:| .|...|.:.||:|.|...|.:.:| |..| |.|..
Yeast    23 ISRSESSESLNS-------LTSTRSSSSNRPKTYFCDYDGCDKAFTRPSILTEHQLSVHQGLRAF 80

  Fly   387 VCAECGKAFVESSKLKRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHVRIHTGDRPFVCPFDAC 451
            .|.:|.|:||:.|.|:||...|:..|||||::  |||..:....|:.|...||  :.|:||.:.|
Yeast    81 QCDKCAKSFVKKSHLERHLYTHSDTKPFQCSY--CGKGVTTRQQLKRHEVTHT--KSFICPEEGC 141

  Fly   452 NKKFAQSTNLKSHILT-HAKAKRNTSISGKSGCSNAESNSQSEDTSANYVKVELQDSVTENHVPF 515
            |.:|.:...|::|||: |..         |..|.:...:.|.        ...|::.::::|.|.
Yeast   142 NLRFYKHPQLRAHILSVHLH---------KLTCPHCNKSFQR--------PYRLRNHISKHHDPE 189

  Fly   516 V 516
            |
Yeast   190 V 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pho	NP_524630.1	Transpos_assoc	<342..382	CDD:290671	13/42 (31%)
		C2H2 Zn finger	359..381	CDD:275368	8/22 (36%)
		COG5048	<386..515	CDD:227381	38/129 (29%)
		zf-C2H2	386..408	CDD:278523	9/21 (43%)
		C2H2 Zn finger	388..408	CDD:275368	9/19 (47%)
		zf-H2C2_2	401..426	CDD:290200	12/24 (50%)
		C2H2 Zn finger	416..438	CDD:275368	6/21 (29%)
		zf-H2C2_2	430..457	CDD:290200	10/26 (38%)
		C2H2 Zn finger	446..468	CDD:275368	9/22 (41%)
PZF1	NP_015512.1	COG5048	46..427	CDD:227381	52/166 (31%)
		C2H2 Zn finger	54..74	CDD:275368	7/19 (37%)
		C2H2 Zn finger	82..102	CDD:275368	9/19 (47%)
		C2H2 Zn finger	110..130	CDD:275368	6/21 (29%)
		C2H2 Zn finger	136..155	CDD:275368	6/18 (33%)
		C2H2 Zn finger	165..185	CDD:275368	3/27 (11%)
		C2H2 Zn finger	196..216	CDD:275368
		C2H2 Zn finger	224..244	CDD:275368
		C2H2 Zn finger	255..277	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910