DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment pho and YY1

DIOPT Version :9

Sequence 1:NP_524630.1 Gene:pho / 43819 FlyBaseID:FBgn0002521 Length:520 Species:Drosophila melanogaster
Sequence 2:NP_849323.1 Gene:YY1 / 826093 AraportID:AT4G06634 Length:387 Species:Arabidopsis thaliana


Alignment Length:238 Identity:78/238 - (32%)
Similarity:112/238 - (47%) Gaps:48/238 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   233 MDHLIKERGNLSQENNISERILSKTTLSFEEPILLPDSSSIELVNETAAMTINNHRTLSNHTGNT 297
            |||     .|...:|....|           |||...:.:::.:.|.....|         ....
plant     1 MDH-----QNYQYQNPFERR-----------PILKSKAPAVKWIKEWVPQDI---------VATG 40

  Fly   298 GDLHALPSSVPFRIGLHEGQVNDCLSTISQSTHQDNTDSTGCGEMNLSEVTVSYTNDKKIACPHK 362
            |..|           ||:....|..|.:.:...          |.::.|.....|.:....|.:.
plant    41 GKCH-----------LHKWVTEDTFSRLKEKEK----------EPDVPEPEPEPTTEILFLCSYD 84

  Fly   363 GCNKHFRDSSAMRKHLHTHGPRVHVCAE--CGKAFVESSKLKRHQLVHTGEKPFQCTFEGCGKRF 425
            ||.|.|.|.||:|||.|.||.|.:||.:  |||.|::|||||||.|:||||:.:.||:|||||.|
plant    85 GCGKTFFDVSALRKHSHIHGERQYVCDQEGCGKKFLDSSKLKRHYLIHTGERNYICTYEGCGKAF 149

  Fly   426 SLDFNLRTHVRIHTGDRPFVCPFDACNKKFAQSTNLKSHILTH 468
            |||||||:|::.|:.:...:||:..|.|::|....||:|:..:
plant   150 SLDFNLRSHMKTHSQENYHICPYSGCVKRYAHEYKLKNHVAAY 192

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
phoNP_524630.1 Transpos_assoc <342..382 CDD:290671 14/39 (36%)
C2H2 Zn finger 359..381 CDD:275368 12/21 (57%)
COG5048 <386..515 CDD:227381 43/85 (51%)
zf-C2H2 386..408 CDD:278523 14/23 (61%)
C2H2 Zn finger 388..408 CDD:275368 13/21 (62%)
zf-H2C2_2 401..426 CDD:290200 16/24 (67%)
C2H2 Zn finger 416..438 CDD:275368 16/21 (76%)
zf-H2C2_2 430..457 CDD:290200 9/26 (35%)
C2H2 Zn finger 446..468 CDD:275368 8/21 (38%)
YY1NP_849323.1 C2H2 Zn finger 84..103 CDD:275368 11/18 (61%)
COG5048 <92..170 CDD:227381 45/77 (58%)
C2H2 Zn finger 110..132 CDD:275368 13/21 (62%)
C2H2 Zn finger 140..162 CDD:275368 16/21 (76%)
C2H2 Zn finger 170..189 CDD:275368 7/18 (39%)
SFP1 <196..274 CDD:227516
C2H2 Zn finger 232..252 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 1 1.000 46 1.000 Domainoid score I4584
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0003443
OrthoInspector 1 1.000 - - otm3448
orthoMCL 1 0.900 - - OOG6_104913
Panther 1 1.100 - - LDO PTHR14003
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X3337
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
109.870

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