DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pho and Zbtb6

DIOPT Version :9

Sequence 1:	NP_524630.1	Gene:	pho / 43819	FlyBaseID:	FBgn0002521	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001102423.1	Gene:	Zbtb6 / 366029	RGDID:	1306007	Length:	423	Species:	Rattus norvegicus

Alignment Length:	411	Identity:	92/411 - (22%)
Similarity:	153/411 - (37%)	Gaps:	124/411 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   171 ISDDEYSGSDQIVGASD--------LLKGKE---------EFG----IDGFTSQQNKEYQKMESK 214
            |:|.|:.|...|:.|..        |.:.|.         |.|    :..:|.....:.:::...
  Rat    39 INDTEFQGHKVILAACSTFMRDQFLLTQSKHIRITILQSAEVGRKLLLSCYTGALEVKRKELLKY 103

  Fly   215 FTNAQTLEMPHPISS-VQIMDHLIKERGNLSQENNISERIL--SKTTLSFEEPILLPDSSSIEL- 275
            .|.|..|:|.|.:.. .:.:...::.  :||.:||....:.  |.|.:..||.....|...||:
  Rat   104 LTAASYLQMVHIVEKCTEALSKYLEI--DLSMKNNQHTDLCQSSDTDVKNEEENSDKDCEIIEIS 166

  Fly   276 ----VN-------------ETAAMTINNHR------TLSNHTG---------------NTGDL-- 300
                ||             ::||.|:.:.|      .||...|               :|.|:
  Rat   167 EDSPVNLDPPVKEEEGDALQSAAETLTSERRGVKSPELSTVDGGFKENEICILHVESIHTDDIEN 231

  Fly   301 --------------------HALPSSVPFRIGLHEGQVNDCLSTISQSTHQDNTDSTGCGEMN-L 344
                                |::.:|..      |.:|.:.....:|....:|:|.:. |.:| :
  Rat   232 GQFPQPCTSSNAGMYFPETQHSVINSTV------ENRVTEVPGNTNQGLFSENSDGSH-GTINEI 289

  Fly   345 SEVTVSYTNDKKIACPHKGCNKHFRDSSAMRKHLHTHGPRVHVCAECGKAFVESSKLKRHQLVHT 409
            ..:..:::  .:..||.  |.:.|.......:||..|  ::.:|.:|||.|.:...|.||...|.
  Rat   290 QNLDENFS--LRHQCPR--CPRGFLHVENYLRHLKMH--KLFLCLQCGKTFTQKKNLNRHIRGHM 348

  Fly   410 GEKPFQCTFEGCGKRFSLDFNLRTHVRIHTGDRPFVCPFDACNKKFAQSTNLKSHILTHAKAKRN 474
            |.:|||||.  |.|.|:....|:.|:.||:||||:.|  ..|:..|...:.||.|:
  Rat   349 GIRPFQCTV--CLKTFTAKSTLQDHLNIHSGDRPYKC--HCCDMDFKHKSALKKHL--------- 400

  Fly   475 TSISGKSG----------CSN 485
            ||:.|:|.          |.|
  Rat   401 TSVHGRSSGEKLSRPDLKCQN 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pho	NP_524630.1	Transpos_assoc	<342..382	CDD:290671	7/40 (18%)
		C2H2 Zn finger	359..381	CDD:275368	6/21 (29%)
		COG5048	<386..515	CDD:227381	38/110 (35%)
		zf-C2H2	386..408	CDD:278523	8/21 (38%)
		C2H2 Zn finger	388..408	CDD:275368	8/19 (42%)
		zf-H2C2_2	401..426	CDD:290200	12/24 (50%)
		C2H2 Zn finger	416..438	CDD:275368	7/21 (33%)
		zf-H2C2_2	430..457	CDD:290200	11/26 (42%)
		C2H2 Zn finger	446..468	CDD:275368	6/21 (29%)
Zbtb6	NP_001102423.1	BTB_POZ_ZBTB6	8..123	CDD:349506	16/83 (19%)
		COG5048	<251..>398	CDD:227381	46/163 (28%)
		C2H2 Zn finger	302..322	CDD:275368	6/21 (29%)
		zf-C2H2	325..347	CDD:395048	8/21 (38%)
		C2H2 Zn finger	327..347	CDD:275368	8/19 (42%)
		zf-H2C2_2	339..363	CDD:404364	12/25 (48%)
		C2H2 Zn finger	355..375	CDD:275368	7/21 (33%)
		C2H2 Zn finger	383..400	CDD:275368	5/18 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000