DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment pho and salm

DIOPT Version :9

Sequence 1:NP_524630.1 Gene:pho / 43819 FlyBaseID:FBgn0002521 Length:520 Species:Drosophila melanogaster
Sequence 2:NP_723670.2 Gene:salm / 34569 FlyBaseID:FBgn0261648 Length:1365 Species:Drosophila melanogaster


Alignment Length:280 Identity:66/280 - (23%)
Similarity:99/280 - (35%) Gaps:94/280 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   219 QTLEMPHPISSVQIMDHL--IKERGNL-SQENNISERI-LSKTTLSFEEPILLPDSSSIELVNET 279
            |...:.||.||.....||  :...|.| .:|:..:||. |:.||.....|               
  Fly   691 QPAALMHPQSSPGSQSHLDHLPTPGQLPPREDFFAERFPLNFTTAKMLSP--------------- 740

  Fly   280 AAMTINNHRTLSNHTGNTGDLHALPSSVP---------------FRIGLHEGQVNDCLSTISQST 329
                 .:|..:.:..|.     |||..||               |....||      ::.:....
  Fly   741 -----EHHSPVRSPAGG-----ALPPGVPPPPHHHPHHMARSPFFNPIKHE------MAALLPRP 789

  Fly   330 HQDNTD-------STGCGEMNLSEVTVSYTNDKKIACPHKGCNKHFRDSSAMRKHLHTHGPRVHV 387
            |.::..       |..|..|.|.|:    ..:|||:.|::                         
  Fly   790 HSNDNSWENFIEVSNTCETMKLKEL----MKNKKISDPNQ------------------------- 825

  Fly   388 CAECGKAFVESSKLKRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHVRIHTGDRPF----VCPF 448
            |..|.:.....|.|:.|...||||:||:|..  ||:.|:...||:||:.:|....|.    .|| 
  Fly   826 CVVCDRVLSCKSALQMHYRTHTGERPFKCRI--CGRAFTTKGNLKTHMAVHKIRPPMRNFHQCP- 887

  Fly   449 DACNKKFAQSTNLKSHILTH 468
             .|:||::.:..|:.||..|
  Fly   888 -VCHKKYSNALVLQQHIRLH 906

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
phoNP_524630.1 Transpos_assoc <342..382 CDD:290671 7/39 (18%)
C2H2 Zn finger 359..381 CDD:275368 1/21 (5%)
COG5048 <386..515 CDD:227381 30/87 (34%)
zf-C2H2 386..408 CDD:278523 5/21 (24%)
C2H2 Zn finger 388..408 CDD:275368 5/19 (26%)
zf-H2C2_2 401..426 CDD:290200 11/24 (46%)
C2H2 Zn finger 416..438 CDD:275368 8/21 (38%)
zf-H2C2_2 430..457 CDD:290200 11/30 (37%)
C2H2 Zn finger 446..468 CDD:275368 8/21 (38%)
salmNP_723670.2 zf-C2H2 451..473 CDD:278523
C2H2 Zn finger 453..473 CDD:275368
zf-H2C2_2 465..490 CDD:290200
C2H2 Zn finger 481..501 CDD:275368
C2H2 Zn finger 826..846 CDD:275368 5/19 (26%)
zf-H2C2_2 838..863 CDD:290200 12/26 (46%)
zf-C2H2_2 854..922 CDD:289522 19/57 (33%)
C2H2 Zn finger 854..874 CDD:275368 8/21 (38%)
C2H2 Zn finger 886..906 CDD:275368 8/21 (38%)
C2H2 Zn finger 1291..1311 CDD:275368
zf-H2C2_2 1303..1328 CDD:290200
C2H2 Zn finger 1319..1339 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1943
SonicParanoid 00.000 Not matched by this tool.
11.030

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