DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pho and Zbtb6

DIOPT Version :9

Sequence 1:	NP_524630.1	Gene:	pho / 43819	FlyBaseID:	FBgn0002521	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_666365.1	Gene:	Zbtb6 / 241322	MGIID:	2442998	Length:	423	Species:	Mus musculus

Alignment Length:	302	Identity:	74/302 - (24%)
Similarity:	127/302 - (42%)	Gaps:	62/302 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 TSQQNKEYQKMESKFTNAQTLEMPHPISSVQIMDHLIKERGNLSQ---ENNISERILSKTTLSFE 262
            |..:|:|    |:...:.:.:|:... |.|.:..|:.:|..|..|   |...|||:..::
Mouse   147 TDVKNEE----ENSDKDCEIIEISED-SPVNLDFHVKEEESNALQSAAETLTSERMRMQS----- 201

  Fly   263 EPILLPDSSSIE---LVNETAAMTINNHRTLSNHTGNTGD--------------LHALPSSVPFR 310
                 |:.|:::   ..||...:.:.:..|.....|....              .|:|.:|..
Mouse   202 -----PELSAVDGGFKENEICILHVESISTDDVENGQFSQPCTSSKAGIYFPETQHSLINSTV-- 259

  Fly   311 IGLHEGQVNDCLSTISQSTHQDNTDSTGCGEMN-LSEVTVSYTNDKKIACPHKGCNKHFRDSSAM 374
                |.:|.:.....:|....:|:|.:. |.:| :..:..:::  .:..||.  |.:.|......
Mouse   260 ----ENRVTEVPGNTNQGLFSENSDGSH-GTVNEIQNLDENFS--LRHQCPR--CPRGFLHVENY 315

  Fly   375 RKHLHTHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHVRIHT 439
            .:||..|  ::.:|.:|||.|.:...|.||...|.|.:|||||.  |.|.|:....|:.|:.||:
Mouse   316 LRHLKMH--KLFLCLQCGKTFTQKKNLNRHIRGHMGIRPFQCTV--CLKTFTAKSTLQDHLNIHS 376

  Fly   440 GDRPFVCPFDACNKKFAQSTNLKSHILTHAKAKRNTSISGKS 481
            ||||:.|  ..|:..|...:.||.|:         ||:.|:|
Mouse   377 GDRPYKC--HCCDMDFKHKSALKKHL---------TSVHGRS 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pho	NP_524630.1	Transpos_assoc	<342..382	CDD:290671	7/40 (18%)
		C2H2 Zn finger	359..381	CDD:275368	6/21 (29%)
		COG5048	<386..515	CDD:227381	36/96 (38%)
		zf-C2H2	386..408	CDD:278523	8/21 (38%)
		C2H2 Zn finger	388..408	CDD:275368	8/19 (42%)
		zf-H2C2_2	401..426	CDD:290200	12/24 (50%)
		C2H2 Zn finger	416..438	CDD:275368	7/21 (33%)
		zf-H2C2_2	430..457	CDD:290200	11/26 (42%)
		C2H2 Zn finger	446..468	CDD:275368	6/21 (29%)
Zbtb6	NP_666365.1	BTB	23..123	CDD:279045
		BTB	34..127	CDD:197585
		C2H2 Zn finger	302..322	CDD:275368	6/21 (29%)
		zf-C2H2	325..347	CDD:278523	8/21 (38%)
		C2H2 Zn finger	327..347	CDD:275368	8/19 (42%)
		zf-H2C2_2	339..363	CDD:290200	12/25 (48%)
		C2H2 Zn finger	355..375	CDD:275368	7/21 (33%)
		C2H2 Zn finger	383..400	CDD:275368	5/18 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000