DRSC/TRiP Functional Genomics Resources

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Protein Alignment pho and Zfp13

DIOPT Version :9

Sequence 1:NP_524630.1 Gene:pho / 43819 FlyBaseID:FBgn0002521 Length:520 Species:Drosophila melanogaster
Sequence 2:XP_011244722.1 Gene:Zfp13 / 22654 MGIID:99159 Length:546 Species:Mus musculus


Alignment Length:392 Identity:109/392 - (27%)
Similarity:157/392 - (40%) Gaps:102/392 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   123 GVVDKNSPFLTLG------TTILNSNGKSRRWEQKLVHIKTMEGEFSVTMWASGISDDEYSGSDQ 181
            |..|| .|||..|      |.:|:..|::|  |:|:       ....:|.|           |..
Mouse    79 GPKDK-GPFLPGGVVPSPWTPVLSRGGRTR--ERKM-------AAALLTAW-----------SQM 122

  Fly   182 IVGASD--LLKGKEEFG-IDGFTSQQNKEYQKMESKFTNAQTLEMP--HPISSVQIMDHLIKERG 241
            .|...|  |...:||:| :|  .:|||.....::.|  |...|..|  .|....|     |:.:|
Mouse   123 PVTFEDVALYLSQEEWGRLD--HTQQNFYRDVLQGK--NGLALGFPFSRPFWVPQ-----IQGKG 178

  Fly   242 NLSQENNISERILSKTTLSFEEPILLPDSSSIEL---VNETAAMTINNHRT-------------- 289
                      ::.|:.|.:.|...|  .|.::|:   |...|..|:.:.::              
Mouse   179 ----------QVASRITGAEERRGL--GSGAVEMGKVVPALAVATLEDTKSIRTRARWAPGEDPK 231

  Fly   290 ------------LSNHTGNTGDLHALPS-SVPFRIGLHEGQVNDCLSTISQSTHQDNTDSTGCGE 341
                        |:..||..|.|...|| |.|.:.....|          .....:..::...||
Mouse   232 CGQHVASGPGTKLTRDTGKAGQLKPAPSESRPLKTPEDSG----------PEKPSEGEEALKSGE 286

  Fly   342 MNLSEVTVSYTNDKKIACPHKGCNKHFRDSSAMRKHLHTH-GPRVHVCAECGKAFVESSKLKRHQ 405
            ..|  |....|..|...|  :.|.|.|...|.:..|..|| |.:.:.|.:|||.|..||.|.:||
Mouse   287 EGL--VPDGDTGKKTYKC--EQCGKGFSWHSHLVTHRRTHTGEKPYTCTDCGKRFGRSSHLIQHQ 347

  Fly   406 LVHTGEKPFQCTFEGCGKRFSLDFNLRTHVRIHTGDRPFVCPFDACNKKFAQSTNLKSHILTHAK 470
            ::||||||:.|  ..|.|.||....|..|.|||||::|:||  |.|.|:|.:.::|.:|..||..
Mouse   348 IIHTGEKPYTC--PSCWKSFSHHSTLIQHQRIHTGEKPYVC--DRCAKRFTRRSDLVTHQGTHTG 408

  Fly   471 AK 472
            ||
Mouse   409 AK 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
phoNP_524630.1 Transpos_assoc <342..382 CDD:290671 12/40 (30%)
C2H2 Zn finger 359..381 CDD:275368 6/21 (29%)
COG5048 <386..515 CDD:227381 41/87 (47%)
zf-C2H2 386..408 CDD:278523 10/21 (48%)
C2H2 Zn finger 388..408 CDD:275368 10/19 (53%)
zf-H2C2_2 401..426 CDD:290200 12/24 (50%)
C2H2 Zn finger 416..438 CDD:275368 8/21 (38%)
zf-H2C2_2 430..457 CDD:290200 14/26 (54%)
C2H2 Zn finger 446..468 CDD:275368 7/21 (33%)
Zfp13XP_011244722.1 KRAB 124..179 CDD:214630 18/73 (25%)
C2H2 Zn finger 302..322 CDD:275368 6/21 (29%)
zf-H2C2_2 314..339 CDD:372612 9/24 (38%)
C2H2 Zn finger 330..350 CDD:275368 10/19 (53%)
zf-H2C2_2 342..367 CDD:372612 13/26 (50%)
C2H2 Zn finger 358..378 CDD:275368 8/21 (38%)
COG5048 <360..520 CDD:227381 24/53 (45%)
C2H2 Zn finger 386..406 CDD:275368 7/21 (33%)
C2H2 Zn finger 414..434 CDD:275368
C2H2 Zn finger 442..462 CDD:275368
C2H2 Zn finger 470..490 CDD:275368
C2H2 Zn finger 498..518 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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