DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pho and Zfp143

DIOPT Version :9

Sequence 1:	NP_524630.1	Gene:	pho / 43819	FlyBaseID:	FBgn0002521	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_006507593.2	Gene:	Zfp143 / 20841	MGIID:	1277969	Length:	653	Species:	Mus musculus

Alignment Length:	412	Identity:	97/412 - (23%)
Similarity:	150/412 - (36%)	Gaps:	124/412 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 FSVTMWASGISDDEYSGSDQIVGASDLLKGKEEFGIDGFTSQ-------------QNKEYQKMES 213
            ||..|..:.|:.|.              :|..||...|..:|             .....:.||.
Mouse    12 FSEKMLLAQINRDS--------------QGMTEFPGGGMEAQHVTLCLTEAVTVADGDNLENMEG 62

  Fly   214 KFTNAQTLE------MPHPISSVQIMDHLI--KERGNLSQENNISERILSKTTLSFEEPILLPDS 270
            ....|.||.      :.|.....:::|..:  .|.|:.:...::.   :.|:|   .:.:.|.|.
Mouse    63 VSLQAVTLADGSTAYIQHNSKDGRLIDGQVIQLEDGSAAYVQHVP---IPKST---GDSLRLEDG 121

  Fly   271 SSIELVNETAAMTINNHRTLSN------------HTGNTGDLH---ALPSSVPFR--------IG 312
            .:::|.:.|.|..   |.|..:            ..|.|..:|   .:|.|....        .|
Mouse   122 QAVQLEDGTTAFI---HHTSKDSYDQSSLQAVQLEDGTTAYIHHAVQVPQSDTILAIQADGTVAG 183

  Fly   313 LHEGQVN---DCLSTISQSTHQ------DNTDST------------------------------- 337
            ||.|...   |.:|.:.|...:      |...||
Mouse   184 LHTGDATIDPDTISALEQYAAKVSIDGSDGVTSTGMIGENEQEKKMQIVLQGHATRVTPKSQQSG 248

  Fly   338 ---------GCGEM-----NLSEVTVSYTNDKKIACPHKGCNKHFRDSSAMRKHLHTH-GPRVHV 387
                     |||::     :|.....|:|.|:...|.|.||.|.|.....::.|..|| |.:.:.
Mouse   249 EKAFRCKYDGCGKLYTTAHHLKVHERSHTGDRPYQCEHSGCGKAFATGYGLKSHFRTHTGEKPYR 313

  Fly   388 CAE--CGKAFVESSKLKRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHVRIHTGDRPFVCPFDA 450
            |:|  |.|:|..|..|::|...||||:||:|..||||:.|:.....:.|:|.|||:||:.|....
Mouse   314 CSEDNCTKSFKTSGDLQKHIRTHTGERPFKCPIEGCGRSFTTSNIRKVHIRTHTGERPYYCTEPG 378

  Fly   451 CNKKFAQSTNLKSHILTHAKAK 472
            |.:.||.:||.|:|:..|...|
Mouse   379 CGRAFASATNYKNHVRIHTGEK 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pho	NP_524630.1	Transpos_assoc	<342..382	CDD:290671	13/45 (29%)
		C2H2 Zn finger	359..381	CDD:275368	7/21 (33%)
		COG5048	<386..515	CDD:227381	37/89 (42%)
		zf-C2H2	386..408	CDD:278523	8/23 (35%)
		C2H2 Zn finger	388..408	CDD:275368	8/21 (38%)
		zf-H2C2_2	401..426	CDD:290200	13/24 (54%)
		C2H2 Zn finger	416..438	CDD:275368	8/21 (38%)
		zf-H2C2_2	430..457	CDD:290200	10/26 (38%)
		C2H2 Zn finger	446..468	CDD:275368	8/21 (38%)
Zfp143	XP_006507593.2	SFP1	<222..307	CDD:227516	15/84 (18%)
		C2H2 Zn finger	254..276	CDD:275368	4/21 (19%)
		COG5048	<266..439	CDD:227381	51/135 (38%)
		C2H2 Zn finger	284..306	CDD:275368	7/21 (33%)
		C2H2 Zn finger	314..336	CDD:275368	8/21 (38%)
		C2H2 Zn finger	344..366	CDD:275368	8/21 (38%)
		C2H2 Zn finger	374..396	CDD:275368	8/21 (38%)
		C2H2 Zn finger	404..426	CDD:275368
		C2H2 Zn finger	434..453	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010