DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pho and ZNF367

DIOPT Version :9

Sequence 1:	NP_524630.1	Gene:	pho / 43819	FlyBaseID:	FBgn0002521	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_710162.1	Gene:	ZNF367 / 195828	HGNCID:	18320	Length:	350	Species:	Homo sapiens

Alignment Length:	165	Identity:	49/165 - (29%)
Similarity:	75/165 - (45%)	Gaps:	24/165 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   353 NDKKIACPHKGCNKHFRDSSAMRKHLHTH-GPRVHVC--AECGKAFVESSKLKRHQLVHTGEKPF 414
            :..:|.|  ..||:.|....:::.|..|| |.|.::|  .:||||||:|.:||.||.:|||||||
Human   163 SSSRIRC--NICNRVFPREKSLQAHKRTHTGERPYLCDYPDCGKAFVQSGQLKTHQRLHTGEKPF 225

  Fly   415 QCTFEGCGKRFSLDFNLRTHVRIHTGDRPFVC-----PFDACNKKFAQSTNLKSHILT---HAKA 471
            .|:..||..||       ||...|....|:..     |.|..:|..|......:..|.   ..:.
Human   226 VCSENGCLSRF-------THANRHCPKHPYARLKREEPTDTLSKHQAADNKAAAEWLARYWEMRE 283

  Fly   472 KRNTSISGKSGCSNAESNSQSEDTSANYVKVELQD 506
            :|..::.||.    .:...|.:.....|::.:.:|
Human   284 QRTPTLKGKL----VQKADQEQQDPLEYLQSDEED 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pho	NP_524630.1	Transpos_assoc	<342..382	CDD:290671	8/29 (28%)
		C2H2 Zn finger	359..381	CDD:275368	5/21 (24%)
		COG5048	<386..515	CDD:227381	39/131 (30%)
		zf-C2H2	386..408	CDD:278523	12/23 (52%)
		C2H2 Zn finger	388..408	CDD:275368	12/21 (57%)
		zf-H2C2_2	401..426	CDD:290200	15/24 (63%)
		C2H2 Zn finger	416..438	CDD:275368	7/21 (33%)
		zf-H2C2_2	430..457	CDD:290200	7/31 (23%)
		C2H2 Zn finger	446..468	CDD:275368	5/29 (17%)
ZNF367	NP_710162.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	104..151
		COG5048	167..>240	CDD:227381	36/81 (44%)
		zf-C2H2	168..189	CDD:278523	5/22 (23%)
		C2H2 Zn finger	169..189	CDD:275368	5/21 (24%)
		zf-H2C2_2	181..208	CDD:290200	11/26 (42%)
		C2H2 Zn finger	197..219	CDD:275368	12/21 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	290..327		5/29 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1943
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030