DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pho and Zfp42

DIOPT Version :9

Sequence 1:	NP_524630.1	Gene:	pho / 43819	FlyBaseID:	FBgn0002521	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_002728454.2	Gene:	Zfp42 / 100361947	RGDID:	2319133	Length:	305	Species:	Rattus norvegicus

Alignment Length:	321	Identity:	126/321 - (39%)
Similarity:	157/321 - (48%)	Gaps:	73/321 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 KGKEEFGIDGFTSQQNKEYQKMESKFTNAQTLEMPHPISSVQIMDHLIKERGNLSQEN------- 247
            ||.....:|..|...:      |::......:|.||       :.:.|.|.|.:|.||
  Rat    15 KGPGRRALDRMTLNHD------EARPVQNTRVEPPH-------VTYTIHEEGEISPENEEDVFPN 66

  Fly   248 ---------NISERILSKTTLSFEEPILLPDSSSIELVNETAAMTINNHRTLSNH--TGNTGDLH 301
                     ..||.||       ||.:|.....|:|...:..:..:....:|..:  .|...:..
  Rat    67 GYLECIIRGEFSEPIL-------EEDLLFKSFESLEEAEQDLSCQVLEASSLLEYMTKGTKQEKR 124

  Fly   302 ALPSSVPFRIGLHEGQVNDCL-------------STISQSTHQDNTDSTG--------CGEMNLS 345
            |........:|.:  .|.:|.             |.:..|.|:..:..||        ||.:::.
  Rat   125 ATQEEPQQTVGAN--SVPECSEYLTSRKLPVGEPSEVDLSYHEQLSGFTGEKLKGGPYCGNISML 187

  Fly   346 EVTVSYTNDKKIACPHKGCNKHFRDSSAMRKHLHTHGPRVHVCAECGKAFVESSKLKRHQLVHTG 410
            |            ||..||.|..||.:|:|||:..||||.||||||||||.||||||||.|||||
  Rat   188 E------------CPQAGCKKKLRDKTALRKHMLVHGPRQHVCAECGKAFTESSKLKRHFLVHTG 240

  Fly   411 EKPFQCTFEGCGKRFSLDFNLRTHVRIHTGDRPFVCPFDACNKKFAQSTNLKSHILTHAKA 471
            |:||||||||||||||||||||||||||||::.||||||.|.|.|.||.|||.||||||||
  Rat   241 ERPFQCTFEGCGKRFSLDFNLRTHVRIHTGEKRFVCPFDGCEKSFIQSNNLKIHILTHAKA 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pho	NP_524630.1	Transpos_assoc	<342..382	CDD:290671	12/39 (31%)
		C2H2 Zn finger	359..381	CDD:275368	11/21 (52%)
		COG5048	<386..515	CDD:227381	74/86 (86%)
		zf-C2H2	386..408	CDD:278523	19/21 (90%)
		C2H2 Zn finger	388..408	CDD:275368	17/19 (89%)
		zf-H2C2_2	401..426	CDD:290200	22/24 (92%)
		C2H2 Zn finger	416..438	CDD:275368	21/21 (100%)
		zf-H2C2_2	430..457	CDD:290200	20/26 (77%)
		C2H2 Zn finger	446..468	CDD:275368	15/21 (71%)
Zfp42	XP_002728454.2	C2H2 Zn finger	189..211	CDD:275368	11/21 (52%)
		COG5048	<215..>290	CDD:227381	63/74 (85%)
		C2H2 Zn finger	218..238	CDD:275368	17/19 (89%)
		C2H2 Zn finger	246..268	CDD:275368	21/21 (100%)
		C2H2 Zn finger	276..298	CDD:275368	15/21 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D362296at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010