Protein Alignment MED26 and DST1

DIOPT Version :10

• Sequence 1: NP_651936.1
• Gene: MED26 / 43816
• FlyBaseID: FBgn0039923
• Length: 1483
• Species: Drosophila melanogaster
• Sequence 2: NP_011472.1
• Gene: DST1 / 852839
• SGDID: S000003011
• Length: 309
• Species: Saccharomyces cerevisiae
• Alignment Length: 306
• Identity: 55/306 - (17%)
• Similarity: 119/306 - (38%)
• Gaps: 70/306 - (22%)

  Fly     4 IEIQELTTHLSQALDQNYDVVNMDAVLCVICALEGTTI-TKEQLEATRLAKYINQLRRRTKNEHL 67
            ::.:|:..|:.. |::|..  |..|||.::..|:...: |::.|..|::...:|:.::.| |..:
Yeast     1 MDSKEVLVHVKN-LEKNKS--NDAAVLEILHVLDKEFVPTEKLLRETKVGVEVNKFKKST-NVEI 61

  Fly    68 ARRAKSLLKKWREMVGIQQTATENLAHPSQISSSQPALDLVKSPITSFITEPIAPSQQIVSDLHS 132
            ::..|.::..|::.:...:.:.:...|....:...                  |..:..|.:
Yeast    62 SKLVKKMISSWKDAINKNKRSRQAQQHHQDHAPGN------------------AEDKTTVGE--- 105

  Fly   133 NIDSAEPPLSGEHTLLHPNFSNLVNSIKDSDRHENIAITTLHTHKDR-------------RHSHS 184
            :::..:.|.|.:...:..:  ..|::...:.:::.:. |.::.||.|             ...|.
Yeast   106 SVNGVQQPASSQSDAMKQD--KYVSTKPRNSKNDGVD-TAIYHHKLRDQVLKALYDVLAKESEHP 167

  Fly   185 IRS-CHVASPQPIVIDHSVNSVINL-TDDSTVKINEASVVIDIAS----DSDENDNNGSLNPKKL 243
            .:| .|.|.    .|:..:|.|.|. |:::..|.....:..::.|    |......||.:.|:.|
Yeast   168 PQSILHTAK----AIESEMNKVNNCDTNEAAYKARYRIIYSNVISKNNPDLKHKIANGDITPEFL 228

  Fly   244 -----NSIVPAPLPIPSTPSSRQRKLKKEKRSKER--EGQVATNTR 282
                 ..:.||||           |.|.|:.:|:.  ..|.||..|
Yeast   229 ATCDAKDLAPAPL-----------KQKIEEIAKQNLYNAQGATIER 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MED26	NP_651936.1	TFSII	13..>129	CDD:273592	18/116 (16%)
		Med26	32..82	CDD:462573	9/50 (18%)
DST1	NP_011472.1	TFSII	3..309	CDD:273592	55/304 (18%)