Protein Alignment MED26 and Med26

DIOPT Version :10

• Sequence 1: NP_651936.1
• Gene: MED26 / 43816
• FlyBaseID: FBgn0039923
• Length: 1483
• Species: Drosophila melanogaster
• Sequence 2: XP_038950406.1
• Gene: Med26 / 306328
• RGDID: 1309524
• Length: 609
• Species: Rattus norvegicus
• Alignment Length: 695
• Identity: 146/695 - (21%)
• Similarity: 230/695 - (33%)
• Gaps: 270/695 - (38%)

  Fly    25 NMDAVLCVICALEGTTITKEQLEATRLAKYINQLRRRTKNEHLARRAKSLLKKWREMV------- 82
            ||.|||.||.:||...||||.||.|||.|.||.:|::||||.||:|||.||:.|::::
  Rat    48 NMVAVLEVISSLERYPITKEALEETRLGKLINDVRKKTKNEELAKRAKRLLRSWQKLIEPVHQNE 112

  Fly    83 -------GIQQTATENLAH-----------PSQISSSQPALDLVKSP------------------ 111
                   |...:|... ||           |..|...:...|:.:.|
  Rat   113 VALRALAGAAGSANGG-AHNCRPELGVAGAPKSIHDLKNRNDIQRLPGQRLDRLGSRKRRGDQRD 176

  Fly   112 ---------ITSFITEPIAPSQQIVSDLHSNIDSAEP-----PLSGE-HTLLHPNFSNLVNSIKD 161
                     ::....:|:.|:   .|.|.:|..|..|     ||.|. |  |.|:.|.|  .:.:
  Rat   177 LGHPGPPHKVSKGSPDPLVPN---ASPLPTNGISGSPESLPSPLDGSGH--LGPDGSRL--ELSE 234

  Fly   162 SDRHE-NIAITTLH----------------------------------------------THKDR 179
            :::|. .|.:..:.                                              :.::.
  Rat   235 NEKHSTKIPVNAVRPRPSSPGLGKPPVPCLQTKAAQLQPLDRADEPPGPPYPRGSPRCSISPRNS 299

  Fly   180 RHSHSI---RSCH-----VASPQPIVIDHSVNSVINLTDDSTVKINEASVVIDIASDSDENDNNG 236
            ||..|.   ||.:     |:||.|
  Rat   300 RHEGSFARHRSSYIPKGPVSSPSP----------------------------------------- 323

  Fly   237 SLNPKKLNSI-VPAPLPI--PSTPSSRQRKLKKEKRS-----KEREGQVATNTRFGAKASDGFQQ 293
              .|:.|::. ||:|||:  |.||..|:..|.....|     ::.||    :.|....|.    :
  Rat   324 --RPQPLDTTQVPSPLPLAQPPTPPVRRLDLLPNAESPVHWPEQPEG----HPRLTGPAC----R 378

  Fly   294 AALTTDSEIFSLSNSSMSSIVSGDATSSYSQNKSRLNSNELTFTGRFKAVDHLFRSTESGKHKID 358
            |.|:.||   |.::|..:|  ||   .|.|:.|.|....:.|..
  Rat   379 AGLSPDS---SKADSDAAS--SG---GSDSKKKKRYRPRDYTVN--------------------- 414

  Fly   359 EYSAYDSNASCSRLSPSTVDEVKKAEHLFDAQLTNTTANQI-PMSAVSIGYESNTRHEYLESDSP 422
                .|...:.:.:.|..:.|.|..   ||..     ..|| |:          |:.|.:.:|||
  Rat   415 ----LDGQVAEAGVKPVRLKERKLT---FDPM-----TRQIRPL----------TQKEPVRADSP 457

  Fly   423 ---SQIPKRRGRKKGSKGVDALIAKESSSLSQQIFFGGSTVKKVKTTKELFNEIQSRKLSVSMQS 484
               .|:|:..            :.::.:..|.|..|..:..|::..     |||....|  |.||
  Rat   458 VPTEQLPRTE------------LEQQEAKASLQSPFEQTNWKELSR-----NEIIQSYL--SRQS 503

  Fly   485 SASNLSNSSTNRDLPSHTTFPRQTSSCSDTSMNSPHILETLSGSAIFASKIDDLGNTDSDTVTSD 549
            |..:.|.:.|.........:.:|..| |......||:|..|...........::...|.|.:.:.
  Rat   504 SLLSSSGAQTPGAHHFMAEYLKQEES-SRQGARQPHVLLPLPTPTDLPGLTREVTQDDLDRIQAQ 567

  Fly   550 PSHDSNKSQEIK-------ECTSLDSNSNSIQSLPLANNRENLIP 587
            .....|..::.:       :|.|||.:.:        :.|.|::|
  Rat   568 QWPGVNGCEDTQGNWYDWTQCISLDPHGD--------DGRLNILP 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MED26	NP_651936.1	TFSII	13..>129	CDD:273592	44/155 (28%)
		Med26	32..82	CDD:462573	29/49 (59%)
Med26	XP_038950406.1	TFS2N	47..107	CDD:197766	34/58 (59%)
		Med26_M	199..426	CDD:464807	56/314 (18%)
		Med26_C	428..607	CDD:464806	45/223 (20%)