Protein Alignment bt and Ptk7

DIOPT Version :9

• Sequence 1: NP_001162825.1
• Gene: bt / 43814
• FlyBaseID: FBgn0005666
• Length: 8933
• Species: Drosophila melanogaster
• Sequence 2: NP_001382670.1
• Gene: Ptk7 / 301242
• RGDID: 1310472
• Length: 1062
• Species: Rattus norvegicus
• Alignment Length: 1046
• Identity: 225/1046 - (21%)
• Similarity: 374/1046 - (35%)
• Gaps: 272/1046 - (26%)

  Fly   118 APTFAKKPAIRQEEDGKRLLFECRVNA-DPIPAIIWFHNGAAVKESERHKITVDKDVHSYFATLE 181
            |..|.|:|:.:....|:|.|..|.|.| ||: .:.|..||..|:::||.           ||...
  Rat    23 AIVFIKEPSSQDALQGRRALLRCEVEAPDPV-HVYWLLNGVPVQDTERR-----------FAQGS 75

  Fly   182 ILNVT----VEDAGKYKVNAKNEL-GES--NATISLNFDSDEA-PV----PESAEGIKPTFTERP 234
            .|:..    ::|:|.::..|::.: ||.  :|..|.|....|| ||    |.||..|:|
  Rat    76 SLSFAAVDRLQDSGAFQCVARDNITGEEARSANASFNIKWIEAGPVVLKHPASAAEIQP------ 134

  Fly   235 VIRQSEDGGNVTFECRCVGDPTPTVTWSHGETELNESNRYKMSLTMDQKLYHIAC----LEISSV 295
               |::    ||..|...|.|.||..|....|.|::          ||..:.::.    |.:...
  Rat   135 ---QTQ----VTLRCHIDGHPRPTYQWFRDGTPLSD----------DQSTHTVSSKERNLTLRPA 182

  Fly   296 VSSDQGEYRAQAKNKHGSGVATINLNFESGSKKIPDGKSPRF---PKKPTIRQEEDLLIMECVLE 357
            .....|.|...|.|..|...::.|...     .|.|....|.   |:...:.:.|:.: ..|...
  Rat   183 SPEHSGLYSCCAHNAFGQACSSQNFTL-----SIADESFARVLLAPQDVVVARNEEAM-FHCQFS 241

  Fly   358 AHPVPDIVW-YCSEKEICNNQRTKMTRKAITKDSYILTLEIQNPTKEDGGNYRCNAINMYG---- 417
            |.|.|.:.| :..|..|.|..|....|||:...:..|.|....|  .:.|.|||......|
  Rat   242 AQPPPSLQWVFEDETPITNRSRPPHLRKAMVFANGSLLLTQVRP--RNAGVYRCIGQGQRGPPIV 304

  Fly   418 -ESNANIALNFQGASDANGFAPSFIEKPRIIPNESGTLIT---MKCKCKAK---PEPTVTW-YRG 474
             |:..::|                 |...::|.|....|.   .:..|.|.   |.|:|.| :.|
  Rat   305 LEATLHLA-----------------EIEDMLPLEPRVFIAGGEERVACPAPQGLPTPSVWWEHAG 352

  Fly   475 QDLVE----KSKKIKINTTVIAEDTYELTLEIKDPGATDGGTYRCNVKNEYGESNANLNLNIEAE 535
            ..|..    ..|.:::....|||              :|.|.|.|:..|..|:...::|:.:...
  Rat   353 VRLPAHGRVHQKGLELVFATIAE--------------SDAGVYTCHAANLAGQRRQDVNITVATV 403

  Fly   536 PEPEGEGPTFIEKPRIVSENNGKLVIMECKVKADPKPDVIWFRNGEVIKESNKIKTFIEQRGDQY 600
                   ||::.||:......||...:.|..:|.|||.|||:||..:|.|.::.:  :.:.|
  Rat   404 -------PTWLRKPQDSQLEEGKPGYLHCLTQATPKPTVIWYRNQMLISEDSRFE--VSKNG--- 456

  Fly   601 YIKLELLDPQLEDSGLYKCNIKNTLGELNANLTLNIEIVPVIKDKP-----KIIKIIKKRTVVIE 660
              .|.:...::.|..:|:|......|.:.|.  ..::::..:|..|     :.::..|:.||  .
  Rat   457 --TLRINSVEVYDGTVYRCVSSTPAGSIEAQ--ARVQVLEKLKFTPPPQPQQCMEFDKEATV--P 515

  Fly   661 CTVASKFEPKCTWYK-ETSTVKESKRHVYQVEQTKEGEFAVKLEINDVEESDKGAYKLVASNE-K 723
            |:...:.:|...|.: :.|::.|     :..:......||      .|...|.|.|..:|||| :
  Rat   516 CSATGREKPTVKWVRADGSSLPE-----WVTDNAGTLHFA------RVTRDDAGNYTCIASNEPQ 569

  Fly   724 GEAVSQIVNLVDI-----PEEERKPCKPEISRKLADQKVAESKTFELLVSLSQTDRKCKVEWYKG 783
            |:..:.:...|.:     .|.||             ..|.:..| .||...:|.|.|..::|...
  Rat   570 GQIRAHVQLTVAVFITFKVEPER-------------TTVYQGHT-ALLRCEAQGDPKPLIQWKGK 620

  Fly   784 STVIRETK----------------DITTTFDGTTARLTFSSARTEHTS----------------- 815
            ..::..||                |:.....|:...:..:|....||.
  Rat   621 DRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGSYTCIAGNSCNIRHTEAPLLVVDKPLMEDSEGP 685

  Fly   816 ----NYKVIVTNEVGKDESSCKITVEKVAK-----KKEEKPKEKEKTKNEKEVEQKEMEEDKNES 871
                .||:|.|  :|....:....:..|..     ||..|.|..:|....:|.|.:.:.....::
  Rat   686 GSPPPYKMIQT--IGLSVGAAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQN 748

  Fly   872 GQSVAQTEGRINIEQI-----------SEGD----PKEELTVKEEI--LDKRDTQEVKESSVELQ 919
            ||..|:.:..:.:..:           |.||    |:..|   :.|  |.|.:..||..:..:..
  Rat   749 GQPSAEIQEEVALTSLGSGPTATNKRHSTGDKMHFPRASL---QPITTLGKSEFGEVFLAKAQGL 810

  Fly   920 DSAGHEVPEPKKATSDSKLDQSNQKNLDKKHKTDQSESKTNKNV-------SLAEP--------- 968
            |....|.....|    |..::..|:.||.:.:.:......:.||       ..|||
  Rat   811 DEGATETLVLVK----SLQNKDEQQQLDFRREFEMFGKLNHANVVRLLGLCREAEPHYMVLEYVD 871

  Fly   969 ---------IKSNKQESEEQQ--ATEQIGLKKVDRKASIVSVKEEISSD-------VRRKSTIKA 1015
                     |..||.|..:.|  :|:|    ||...:.:....|.:|::       ..|...:.|
  Rat   872 LGDLKQFLRISKNKDEKLKSQPLSTKQ----KVALCSQVALGMEHLSNNRFVHKDLAARNCLVSA 932

  Fly  1016 KEEITV 1021
            :.::.|
  Rat   933 QRQVKV 938

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bt	NP_001162825.1	I-set	9..101	CDD:254352
		Ig	26..100	CDD:143165
		I-set	119..210	CDD:254352	26/98 (27%)
		Ig	136..209	CDD:143165	21/80 (26%)
		I-set	228..320	CDD:254352	20/95 (21%)
		IGc2	242..312	CDD:197706	17/73 (23%)
		I-set	335..425	CDD:254352	24/98 (24%)
		Ig	350..423	CDD:143165	21/78 (27%)
		Ig	436..530	CDD:299845	22/104 (21%)
		I-set	438..532	CDD:254352	23/104 (22%)
		I-set	545..636	CDD:254352	23/90 (26%)
		Ig	560..633	CDD:143165	19/72 (26%)
		Ig	657..731	CDD:143165	17/75 (23%)
		I-set	746..835	CDD:254352	20/125 (16%)
		Ig	1496..1586	CDD:299845
		IG_like	1503..1588	CDD:214653
		I-set	1639..1724	CDD:254352
		IG	1750..1821	CDD:214652
		IGc2	1750..1806	CDD:197706
		I-set	1826..1909	CDD:254352
		Ig	1831..1897	CDD:299845
		I-set	1914..1998	CDD:254352
		Ig	2020..2095	CDD:299845
		FN3	2100..2194	CDD:238020
		FN3	2203..2292	CDD:238020
		I-set	2311..2395	CDD:254352
		Ig	2321..2395	CDD:299845
		FN3	2399..2493	CDD:238020
		FN3	2501..2590	CDD:238020
		I-set	2602..2693	CDD:254352
		Ig	2619..2693	CDD:299845
		FN3	2697..2793	CDD:238020
		FN3	2801..2893	CDD:238020
		I-set	2902..2995	CDD:254352
		Ig	2919..2993	CDD:299845
		FN3	2999..3088	CDD:238020
		FN3	3102..3191	CDD:238020
		I-set	3208..3292	CDD:254352
		Ig	3219..3292	CDD:299845
		FN3	3296..3390	CDD:238020
		FN3	3400..3489	CDD:238020
		I-set	3494..3590	CDD:254352
		Ig	3516..3590	CDD:299845
		FN3	3594..3682	CDD:238020
		FN3	3694..3781	CDD:238020
		I-set	3795..3885	CDD:254352
		Ig	3813..3885	CDD:299845
		FN3	3889..3980	CDD:238020
		FN3	3990..4082	CDD:238020
		I-set	4090..4181	CDD:254352
		Ig	4108..4181	CDD:299845
		FN3	4185..4271	CDD:238020
		FN3	4285..4383	CDD:238020
		Ig	4404..4480	CDD:299845
		FN3	4484..4571	CDD:238020
		FN3	4584..4677	CDD:238020
		I-set	4685..4775	CDD:254352
		Ig	4703..4775	CDD:299845
		FN3	4779..4863	CDD:238020
		FN3	4879..4970	CDD:238020
		IG	4989..5069	CDD:214652
		Ig	4996..5069	CDD:299845
		FN3	5073..5166	CDD:238020
		FN3	5175..5265	CDD:238020
I-set	5276..5366	CDD:254352
Ig	5293..5366	CDD:299845
FN3	5370..5462	CDD:238020
FN3	5470..5561	CDD:238020
Ig	5559..5654	CDD:299845
I-set	5570..5660	CDD:254352
FN3	5664..5755	CDD:238020
FN3	5764..5853	CDD:238020
I-set	5865..5954	CDD:254352
Ig	5882..5954	CDD:299845
FN3	5958..6049	CDD:238020
FN3	6062..6153	CDD:238020
I-set	6173..6255	CDD:254352
Ig_Titin_like	6182..6255	CDD:143225
FN3	6259..6350	CDD:238020
FN3	6359..6451	CDD:238020
FN3	6470..6552	CDD:238020
I-set	6564..6650	CDD:254352
Ig_Titin_like	6577..6650	CDD:143225
FN3	6654..6745	CDD:238020
FN3	6754..6840	CDD:238020
I-set	6855..6946	CDD:254352
Ig	6874..6946	CDD:299845
FN3	6950..7042	CDD:238020
FN3	7050..7139	CDD:238020
FN3	7151..7237	CDD:238020
I-set	7254..7334	CDD:254352
Ig	7272..7339	CDD:143165
IG_like	7354..7440	CDD:214653
Ig	7366..7440	CDD:299845
FN3	7444..7531	CDD:238020
FN3	7545..7637	CDD:238020
I-set	7648..7737	CDD:254352
Ig	7665..7734	CDD:143165
Ig	7760..7833	CDD:299845
FN3	7837..7927	CDD:238020
STKc_Twitchin_like	7986..8244	CDD:271016
S_TKc	7989..8244	CDD:214567
Ig	8311..8394	CDD:299845
I-set	8312..8401	CDD:254352
I-set	8437..8525	CDD:254352
Ig	8455..8519	CDD:143165
I-set	8632..8721	CDD:254352
IGc2	8646..8711	CDD:197706
I-set	8740..8831	CDD:254352
Ig	8757..8826	CDD:143165
I-set	8839..8922	CDD:254352
Ig	8845..>8909	CDD:299845
Ptk7	NP_001382670.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4475
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900