DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bt and ttn-1

DIOPT Version :9

Sequence 1:	NP_001162825.1	Gene:	bt / 43814	FlyBaseID:	FBgn0005666	Length:	8933	Species:	Drosophila melanogaster
Sequence 2:	NP_001346715.1	Gene:	ttn-1 / 266969	WormBaseID:	WBGene00006436	Length:	15188	Species:	Caenorhabditis elegans

Alignment Length:	10025	Identity:	2182/10025 - (21%)
Similarity:	3627/10025 - (36%)	Gaps:	2576/10025 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 DIEWFRSDNKVVEDVRTKFKIQPVGENKYTVVLELDDVVE-TDAGLYKVKAK------NKSGEVS 96
            |::...:.:..||.  |..|:.|| |:|.|..:|..::|| .|..:.:..|.      .|...|.
Worm  5152 DVQVPETSSPTVEP--TVEKLAPV-ESKETSEVEPAEIVEQKDVPVPETSAPTVEPTVEKLAPVE 5213

  Fly    97 ASINLNFTPADEPKEKQI---DGFAPTFAKKPAIRQEEDGKRLLFECRVNADPIPAIIWFHNGAA 158
            :.......||:..::|.:   :..|||.  :|.:.     |....|.:..::..||.|..|....
Worm  5214 SKETSEVEPAEIVEQKDVPVPETSAPTV--EPTVE-----KLAPVESKETSEVQPAEIVEHKDVQ 5271

  Fly   159 VKES-------ERHKIT-VDKDVHSYFATLEIL---NVTVEDAGKYKVNAKNEL---GESNATIS 209
            |.|:       .:.|:. ||....|...|.||:   :|.|.:.....|....|.   |||..|..
Worm  5272 VPETTATTFEPTKEKLAPVDSKETSEVQTAEIVEQKDVPVPETSATTVEPTKEKLAPGESKETSE 5336

  Fly   210 LN----FDSDEAPVPE-SAEGIKPTFTERPVIRQSEDGGNVTFECRCVGD-PTPTVTWSHGET-- 266
            :.    .:..:..||| ||..::||..:...:...|.....|.|.....| |.|..:.|:.|.
Worm  5337 VQQAAIVEQKDVAVPETSATTVEPTKEKLAPVESKETSEIQTAEIVEQKDVPVPETSTSYVEPTK 5401

  Fly   267 ------ELNESNRYKMSLTMDQKLYHIACLEISSVVSSDQGEYRAQAKNKHGSGV---ATINLNF 322
                  |..|::..:.:..::||  .:...|.|:.......|..|..::|..|.:   |.:.
Worm  5402 EKLAPGESKETSEVQQAAIVEQK--DVPVPETSATTVEPTKEKLAPVESKETSEIQQAAVVE--- 5461

  Fly   323 ESGSKKIPDGKSPRFPKKPT------IRQEEDLLIMECVLEAH---PVPDIVWYCSE------KE 372
               .|.:|..::.....:||      :..:|...:.:..:...   |||:......|      ..
Worm  5462 ---QKDVPVPETSATTVEPTKEKLAPVESKETSEVQQAAIVEQKDVPVPEANAPTFEPTVEKLAP 5523

  Fly   373 ICNNQRTKMTRKAITKDSYILTLEIQNPT-------------KEDGGNYRCNAINMYGESNANIA 424
            :.:.:.:::.:.||.:...:...|...||             ||.....:        |:.|:..
Worm  5524 VESKETSEVQQAAIVEQKDVPVPEANAPTVEPTVEKLAPVESKETSVESK--------ETQADAK 5580

  Fly   425 LNFQGASDANGFAPSFIEKPRIIPNESGTLITMKCKCKAKPEPTVTWYRGQDL-VEKSKKIKINT 488
            |..:........|.:.::|      |:...:..:...|.|.|......:..|. ::|....|:..
Worm  5581 LKKEKDDKHKQEADAKLQK------ENDDKLKQEADAKLKKENDDKLKQEADAKLKKENDDKLKQ 5639

  Fly   489 TVIAEDTYELTLEIKDPGATDGGTYRCNVKNEYGE---SNANLNLNIEAEPEPEGEGPTFIEKPR 550
            ...|:...|...::|...|       ..:|.|..:   ..|:..|..|.:.:.:.|....::|
Worm  5640 EADAKLKKENDDKLKQEAA-------AKLKKENDDKLKQEADAKLKKENDDKLKQEADAKLQK-- 5695

  Fly   551 IVSENNGKLVIMECKVKADPKPDVIWFRNGEVIKESNKIKTFIEQRGDQYYIKLELLDPQLEDSG 615
               ||:.||     |.:||.|   :...|.:.:|:....|  :::..|.   ||:    |..|:.
Worm  5696 ---ENDDKL-----KQEADAK---LQKENDDKLKQEADAK--LQKENDD---KLK----QEADAK 5740

  Fly   616 LYKCNIKNTLGELNANLTLNIEIVPVIKDKPK---IIKIIKKRTVVIECTVASKF-EPKCTWYKE 676
            |.|.|......|.:|.|....:      ||.|   ..|:.|:....::....:|. :.|....|:
Worm  5741 LQKENDDKLKQEADAKLQKEND------DKLKQEADAKLKKENDDKLKQEADAKLKKEKHDKLKQ 5799

  Fly   677 TSTVKESKRHVYQVEQ------TKEGEFAVKLEIN---DVEESDKGAYKLVA--SNEKGEAVSQI 730
            .:..|..|.:..:::|      .||.:..:|.|.:   ..|:.||...:..|  ..||.:.:.|.
Worm  5800 EADAKLQKENDDKLKQEADAKLQKENDDKLKQEADAKLQKEKDDKLKQEADAKLKKEKDDKLKQD 5864

  Fly   731 VNLVDIPEEERKPCKPEISRKL-----------ADQKVAESKTFELLVSLSQTDRKCKVEWYKGS 784
            .: ..:.:|:....|.|...||           ||.|:.:.|..:|   ..:.|.|.|.|  |..
Worm  5865 AD-AKLQKEKDDKLKQEADAKLKKEKDDKLKHEADAKLQKEKDDKL---KQEADAKLKKE--KDD 5923

  Fly   785 TV-------IRETKDITTTFDGTTARLTFSSARTEHTSNYKV-IVTNEVGKDESSCKITVEKVAK 841
            .:       :::.||.....:...........:.:|.::.|: ...::..|.|:..|:..||..|
Worm  5924 RLKKDADAKLQKEKDDKLKQEADAKLKKEKDDKLKHEADAKLQKEKDDKLKQEADAKLKKEKDDK 5988

  Fly   842 KKEEK----PKEK-EKTKNEKEVEQKEMEEDK-NESGQSVAQTEGRINIEQISEGDPKEELTVKE 900
            .|:|.    .||| :|.|.|.:.:.|:.::|| .:...:..|.|....::|  |.|.|.:....:
Worm  5989 LKQEADAKLQKEKDDKLKQEADAKLKKEKDDKLKQEADAKLQKEKDDKLKQ--EADAKLKKEKDD 6051

  Fly   901 EILDKRDTQEVKESSVELQDSAGHEVPEPK----KATSDSKL------------DQSNQKNLDKK 949
            ::..:.|.:..||...:|:..|..::.:.|    |..:|:||            |...||..|.|
Worm  6052 KLKQEADAKLQKEKDDKLKQEADAKLKKEKDDKLKQEADAKLKKEKDDKLKQDADAKLQKEKDDK 6116

  Fly   950 HKTD-QSESKTNKNVSLAE----PIKSNKQESEEQQATEQIGLKKVDRKASIVSVKEEISSDVRR 1009
            .|.: .::.|..|:..|..    .:|..|.:..:|:|..::..:|.|:      :|::..:.:::
Worm  6117 LKQEADAKLKKEKDDKLKHEADAKLKKEKDDKLKQEADAKLKKEKDDK------LKQDADAKLKK 6175

  Fly  1010 KSTIKAKEEITVDDKKASSRRSSLAVEESNTESRRSSIIDKKPLEQVDNKPIDANKNPQPLKEEI 1074
            :...|.|.|.   |.|....:.....:|:|.:.::.. .||...|:.||...:||...|  ||:.
Worm  6176 EKDDKLKHEA---DAKLQKEKDDNFKQEANAKLQKEK-DDKLKQEKDDNFKQEANAKLQ--KEKD 6234

  Fly  1075 PRLKPAE----KRRTSKVIEEPKPD----EGLPKLRKASIAQVKEEA-----KPAAPKLKAKAKA 1126
            .:||..:    |:.....:::.|.|    |...||:|....::|:||     |....|||.:|.|
Worm  6235 DKLKQEKDDKLKQEADAKLKKEKDDKLKQEADAKLKKEKDDKLKQEADAKLKKDKDDKLKQEADA 6299

  Fly  1127 KPKYEELPEIPDYERPQLEKYEKSDFTPSDFARDLEIPNKMEKPIIDSGKKEPAVLAQKNGIPK- 1190
            |.|.|:..::......:|:| :|.|....      |...|::|...|..|:|.....:|....|
Worm  6300 KLKKEKDDKLKQEADAKLKK-DKDDKLKQ------EADAKLKKDKDDKLKQEADAKLKKEKDDKL 6357

  Fly  1191 ---KTDIIEQYADEPKGLKVGKGKLPDEGDGRDGAVLKPVIIEPEKEILDLGNKKN-----NQHA 1247
               |.|.::|.|| .|..|....||..|.|    |.||....:..|:..|...||:     .|.|
Worm  6358 KQEKNDKLKQEAD-AKLKKEKDDKLKQEAD----AKLKKEKDDKLKQETDAKLKKDKDDKLKQEA 6417

  Fly  1248 D---KPTVLDIIKQRRRSSIRNLMTKEPIQNESFLGVVLKPVIKDTREQAAPQQAIQLTKANATE 1309
            |   |....|.:||...:.::.  .|:....:...|.:.|.  ||.:.:......::..|.|..:
Worm  6418 DAKLKKDKDDKLKQEADAKLKK--DKDDKLKQEADGKLKKE--KDNKLKQEADGKLKKEKDNKLK 6478

  Fly  1310 QFSPTKAVKAQVADLKKPETLATLEDNYERPVLEKYDPFSIDKTKSEKSTPSIITPDIRGPEVKL 1374
            |.:..| :|.:..|..|.|..|.|:...:..:.::.|.    |.|.:|             :.||
Worm  6479 QEADAK-LKKEKDDKLKQEADAKLKKEKDDKLKQEADA----KLKKDK-------------DDKL 6525

  Fly  1375 PVQ-ETKEEKQKVPKMQPPAPGDPPKIEVIREKRPSLAPEPPSRRGSLIPPADTGRRPSLIINDE 1438
            ..: :.|.:|:|..|::..|.....|.:..:.|:.:.|.....:...|...||..      :..|
Worm  6526 KQEADAKLKKEKDDKLKQEADAKLKKDKDDKLKQEANAKLQKEKDDKLKQEADAK------LQKE 6584

  Fly  1439 KKLRPGEVMDTRLLRPGEVGEGQRRRPSIDVRRPSVQDLEDLINKPSTPLRDVGDGGPPSIVDV- 1502
            |..:..:..|.:|.:.    :..:.:...|.:....:| :.|..:....|:...|.......|.
Worm  6585 KDDKLKQEADAKLKKE----KDDKLKQEADAKLQKEKD-DKLKQEADAKLKKEKDDKLKQEADAK 6644

  Fly  1503 ---QESYSVVEDSTAYLTVGVEGSPAPTFKFYKGVSEIL---EGGRFKFLTDGQTNTITLCMRKC 1561
               ::..:..:::.|              |..|...:.|   :..:.|...|.          |.
Worm  6645 LQKEKDDNFKQEANA--------------KLQKEKDDKLKQEKDDKLKQEADA----------KL 6685

  Fly  1562 KPNDESKYKIVV---------SNIHGEDSAEMQLYVSDSSGMDFRAMLKKRRYQKW--------- 1608
            |...:.|.|...         ..:..|..|:::....|....:..|.|||.:..|.
Worm  6686 KKEKDDKLKQEADAKLKKDKDDKLKQEADAKLKKEKDDKLKQEADAKLKKEKDDKLKQEADAKLK 6750

  Fly  1609 -DKDEQDPNWGDLKETEKPLPALK-----KVERKVESFLSPLIDQFAKEGKDKKVVFEARFS--- 1664
             |||::.....|.|..:.....||     |::::.:..|....|...|:.||.|:..||...
Worm  6751 KDKDDKLKQEADAKLKKDKDDKLKQEADAKLKKEKDDKLKQETDAKLKKDKDDKLKQEADAKLKK 6815

  Fly  1665 ------KPNCKPKWLFRKDEVFTGSKFKFKQENDTYQLIITTPKVEDTGKYTIEIGGVSSTAFLN 1723
                  |.....|....||:       |.|||.|      ...|.|...|...|     :.|.|.
Worm  6816 EKDDKLKQEADAKLKKEKDD-------KLKQEAD------AKLKKEKDDKLKQE-----ADAKLK 6862

  Fly  1724 -------VEEADPTYTFTK--PLKKKLEGFTQHE--TTLECSVSSSMANVHWFKNN--------- 1768
                   .:|||......|  .||::.:|..:.|  ..|:......:...   |:|
Worm  6863 KDKDDKLKQEADAKLKKDKDDKLKQEADGKLKKEKDNKLKQEADGKLKKE---KDNKLKQEADAK 6924

  Fly  1769 TKLESDDPRYLISKDINGNLKLIIKDSVLDDAGLYRCQLDKQPD---KTECNLKVTEYPYKFVKV 1830
            .|.|.||.   :.::.:..||....|.:..:|.   .:|.|:.|   |.|.:.|        :|.
Worm  6925 LKKEKDDK---LKQEADAKLKKDKDDKLKQEAD---AKLKKEKDDKLKQEADAK--------LKK 6975

  Fly  1831 LKSQQCIEKDTVTLACEIDDAMGEVQWLRNGEEIKPDKRIQIVKDGRKRKLVIKDCKVTDAGQFK 1895
            .|..:..::....|..:.||.:.:    ....::|.||..::.::...:....||.|:......|
Worm  6976 EKDDKLKQEADAKLKKDKDDKLKQ----EADAKLKKDKDDKLKQEADAKLKKEKDDKLKQEADAK 7036

  Fly  1896 CTTNA-DTTESEIIINYQNRFNKKLKDTEAVEREKLILD-IELQDQTAPCDWKFNGEPIVPSESI 1958
            ...:. |..:.|.....:...:.|||.....:.:|...| ::|:|||       |...|....||
Worm  7037 LKKDKDDKLKQEADAKLKKDKDDKLKQEADAKLKKEKGDKLKLEDQT-------NQSRIFEETSI 7094

  Fly  1959 EIKNMGGGKHQLIFSSLDM---------SNEG---EITCES---GQLSSKCKLSI---RKGESRP 2005
            |:.::...|.|.|..|...         :.|.   |:.|.:   .|.:.|..:.|   |.|.|:.
Worm  7095 EVTSLLKCKQQAIIVSKSFALCERVVLNAEEPFTLEVFCNAVFVKQRTDKIGIGIIFERSGASKK 7159

  Fly  2006 NIDCPDKFSGPISAPVLLEVPFKVSGTKQTPVEAKLFKDGK------PLPVKDVEVAVTDDKVTF 2064
            :...||:.....   ||.:|...:|.....|...|..|..|      .:.||:.|    .|:.|.
Worm  7160 DESRPDRLDDNC---VLTDVTDGLSILSPPPKAKKHLKKKKKHHKKEKIAVKETE----QDEKTV 7217

  Fly  2065 KIKKPSRDLSGPYQIKISNGQGEDTKDVQIIC---------------QDVPQPPQDVDITDVYQT 2114
            ...||  ::||..:.:.::|..:...||.|..               .|..|  .::.|.:.|.:
Worm  7218 SHLKP--EISGMERKRSNSGSSDIFVDVDIEAGEESIHTDALVDLNFYDYDQ--MELSIFEDYDS 7278

  Fly  2115 -------SCVVSFNPPSDDGGTPI------TKYVIERQDLSKKHGWESVAEVLPSEP-------C 2159
                   .|.||.:..:.|.|..:      |:.|.::..|.|||  :|..:|:..|.       .
Worm  7279 DDDSASIDCDVSLSNVAADDGIDVFPSDGDTQEVEQKVTLPKKH--QSDEDVISKEEENLETSVS 7341

  Fly  2160 LKKIDDLI-------------PKKQYRFRIRAVNAIGQSDPATFKNTILAKDPWDEPGKPKAVDL 2211
            ...|::.:             ||.         :|:||     ..:.::.|....:|
Worm  7342 YGSIEETVSFTIGTGQSIIEHPKS---------HAVGQ-----MNSEVIIKCKTSQP-------- 7384

  Fly  2212 TDWDKDHADLKWEAPETDGGDPITAYIVEYKEKFSNDWVSGKEVDGDARTATVDGLKEGQQYEFR 2276
                  .:|.||                     |.|..|.   :..:....||.|.:
Worm  7385 ------ISDAKW---------------------FCNGMVL---LPDEQVNMTVTGCE-------- 7411

  Fly  2277 VRAVNRAGPGEPSDKTK-------SIIAKCRF----VKPFIVGEGLKNVTVKKGQTIRFDIKYDG 2330
              ||.|.....|.:|..       ||.::...    |.|.|:.:..|.:|.:.|::..:...:.|
Worm  7412 --AVLRLVKFLPQNKGNYHVLIDGSIGSQPAILSGPVPPVILNKLTKPITHQAGKSFTYKFNFMG 7474

  Fly  2331 EPEPAATWVKGTDNLKFDNQRICLDQLERNSSITIKKSVRKDTGKYKLVLSNSSGTIESEAQVVV 2395
            .|.|....:...:.:.||.:....|.:   :|:.|.|..::|.|:|.:||.|..|..||:..:.:
Worm  7475 APAPRLRVLSNGEPVSFDVKYEIYDNI---ASLYIPKMSKRDGGEYTVVLENKYGKDESDLHITM 7536

  Fly  2396 LDRPLPPGGPFEPEEIRA---SHIKMKWKRPDDDGGCEISGYALERMDEETGRWIPAGEVGPNET 2457
            :|.||.|    ...::.|   :....|| .|...|..:|..|.:.|...|:.||...|.|  .|.
Worm  7537 VDTPLKP----RKAQLVALTDTSATFKW-LPPHTGESDILHYIVMRRSTESRRWRNIGHV--QEK 7594

  Fly  2458 SFDFKGLTPNKKYKFRVKAINKEGESEPLETFDAIVARNPYDPPSPPSQPVIDDYDNKSVLLKWK 2522
            :|....|.||:.|.||:.|:|..||..|.|    |:..|..            |||.
Worm  7595 TFTAIELVPNEFYAFRIVAVNGFGEGAPSE----IIEVNTL------------DYDQ-------- 7635

  Fly  2523 RPPSDGGRPITHYIVEIKDKFAPSWSEVAKTDDPNPECNVEGLKEKMVYQFRV-----RAVNKAG 2582
                             ::.|..:..|..|.||  .:.|.|.:.|..:.:..|     |.:.|..
Worm  7636 -----------------EESFDFAGEEELKLDD--VQVNNEVVTEITIEESEVTIEEHRKLKKKS 7681

  Fly  2583 PSEPSQPTDNHLCKHKNLKPQIDRSTFKRVTIKSGRTHKWSVDVLGEPIPELHWSWRDDIPLTNG 2647
            ........:..|.....|:...|.::...:|.:|         .:.:..||...:...:|.:|..
Worm  7682 KKSKKTTDEPELDSEIALEVSSDITSSLEITTES---------TIPDTAPESQETLNVEIAVTET 7737

  Fly  2648 DRIKIEN-------VDYHTDFSITNVLRKDSGFYTLKAENRNGIDRETVELVVLGKP-------S 2698
            ...||.|       .|.:.|.:::::::||......|:...:|:   |.:..:.|||       .
Worm  7738 TVQKITNPSDESAKKDVNEDTAVSSIVKKDDKDVNKKSLPESGL---TTKKEIQGKPEKKIMKKK 7799

  Fly  2699 SPKGPLAVSDVTASGCK--LQWKKPEDDGG-----VPIKEYVVEKMDTATGKWVRVGR---SPGE 2753
            :.|...::|:.:.:..|  .|.|:.|.:..     ..:::.|..|.:| |.|..:...   .||.
Worm  7800 TEKADSSISETSETLTKDLTQTKQSEPEPAKRTTETSVQDEVKRKTET-TSKSKQTTEEHPQPGG 7863

  Fly  2754 KEPPSFDVTGLSLGSEYMFRVSAVNE-EGESEPLT-----------------TLVGVVAKDPFDE 2800
            |...|  ::..|..||    |..|.: |.|::.:|                 |......|:..||
Worm  7864 KSDSS--ISSTSDASE----VKQVQQSESEAQKVTEKPETAKLESKSKMTEDTTKESDNKETVDE 7922

  Fly  2801 -PNKPGTPEVTDYDNQSIS-------LKWAAPNNDGGAPIQKYIIEKKNKNKTEWEKALEIPGDQ 2857
             |.|....:.|:..:.:||       ::.|.|:......:.....|||.|...|.:|
Worm  7923 KPKKKVLKKKTEKSDSTISETSETSAVESAGPSESETQNVAAVDKEKKQKETDEKQK-------- 7979

  Fly  2858 LEATVAGLQEYGEYQFRVIAVNKAGLSPPSDASVPQIVKYKKLKPRIDRSNLKPLLIRAGKPIRY 2922
            |||.:|| ::..|.:.::.|..|...:...||:       ||.|.:.:.::.|....:.....:.
Worm  7980 LEAEIAG-KKSTEQKSKLEAEAKLKRAAEEDAA-------KKQKEKTEAASKKAAAEKLELEKQA 8036

  Fly  2923 DVNVRGEPAPVITWYQND----------KELKPEEL-----------PSSSEIKNIPYNTKISII 2966
            .:|...|...|..  ||:          |:|..|:|           .::.|...:...||....
Worm  8037 QINKAAEADAVKK--QNELDEQNKLEATKKLAAEKLKLEEQSAAKSKQAAEEQAKLDAQTKAKAA 8099

  Fly  2967 ETVRKHTGIYKIIAVNEHGQDEATVEVNILAPPSKPRGPLDVKDVTKDSCKLKWKKPEDDGGKPI 3031
            |   |.||:.|....|:......|||       .||:..:..|...|....:..|   .|..|.:
Worm  8100 E---KQTGLEKDEKSNKDSGSNETVE-------EKPKKKVLKKKTEKSDSSISQK---SDTSKTV 8151

  Fly  3032 SAYQVEKFDKKQGRWVPLGRTSANDTEFDVKGLQEGHEYQFRVKAINEEGESDPLDSDDSIIAKN 3096
            :    |.....:.....:...::...|.|.|     .:.:..:.|.....|...|:::..:| |.
Worm  8152 A----ESAGSSESETQKVADATSKQKETDKK-----QKLEAEITAKKSADEKSKLETESKLI-KA 8206

  Fly  3097 PYDAASKPGTPNIVDYNEHMVKLKWEAPRSDGGAPISGYIIEKKDKFSPIWD------------- 3148
            ..|||.|        ..|...|||.||..:...|......:||:.:.....:
Worm  8207 AEDAAKK--------QKEKEDKLKLEADVASKKAAAEKLELEKQAQIKKAAEADAVKKQKELAEK 8263

  Fly  3149 EILSTNTSVPEATVEGLVEGNIYQFRVRA-VNKAGFSDPSDATEPHLAKPRNLKPYINRDKMKPI 3212
            :.|.:..:..:|..|.|      :...:| :|||..:|.       :.|.:.|.   .::|::..
Worm  8264 QKLESEAATKKAAAEKL------KLEEQAQINKAAEADA-------VKKQKELD---EKNKLEAN 8312

  Fly  3213 KVRAGQPVKFDVDVKGEPAPSLTWFLK----ETELTSTGQVRLENIDYNTKLTLLDTDRKQSGQY 3273
            |..|.:.:|.:.:...:...::....|    ..|.|:..|..||..|.:||    |::.|::
Worm  8313 KKSAAEKLKLEEESAAKSKQTVEEQAKLDAQTKEKTAEKQTGLEKDDKSTK----DSESKET--- 8370

  Fly  3274 KLRAENINGVDEAVVEVIILDKPSKPEGPIEVSDIHKEGCKLKWRKPKDDGGIPITGYVIEKMDT 3338
                     |||         ||.|.              .||.:..|.|..|        ...:
Worm  8371 ---------VDE---------KPKKK--------------VLKKKTEKSDSSI--------SQKS 8395

  Fly  3339 ATGKWV-----PAGSVDPEKYDI--EIKGLDPNHRYQFRVKAVNEEGESEPLETESAITAKNPFD 3396
            .|.|.|     |:.|...:..|.  :.|..|...:.:..:.|.....|...||.||.:  |...:
Worm  8396 VTSKTVVESGGPSESETQKVADAARKQKETDEKQKLEAEITAKKSADEKSKLEAESKL--KKAAE 8458

  Fly  3397 VSAPPGLPELEDWDEHHVKLKWEPPIRDGGSPITNYIIEVMD-KDSGEFVKAVETDSPVCKGVVK 3460
            |.|.....|.::    .:||..|...:...:       |.:: :...:..||.|.|:     |.|
Worm  8459 VEAAKKQKEKDE----QLKLDTEAASKKAAA-------EKLELEKQAQIKKAAEADA-----VKK 8507

  Fly  3461 KLEEGQQYKFRVRAVNKAGPSDPSEQTNWHVAKPRFLKPHIDRVNLKPVIVKTGLSISLDINIRG 3525
            :.|..::.|....|..|                    |...:::.|:....|...:.|::.....
Worm  8508 EKELAEKQKLESEAATK--------------------KAAAEKLKLEEQKKKDAETASIEKQKEQ 8552

  Fly  3526 EPAPKVEWFFNNSSVTSDEHSVKIDNVDYNTKFFVMRAQRSQSGKYIIKATNEVGEDEAELEVTV 3590
            |            .:..::..:::|            |::|...:.:...|.....:||..|
Worm  8553 E------------KLAQEQSKLEVD------------AKKSAEKQKLESETKSKKTEEAPKE--- 8590

  Fly  3591 LGKPGKPKGPLQVNDITKHSCKLKWEKPDDDGGSPIDYYEIEKLDPHTGQWLPCGKSTEPEAKVI 3655
             ....|||         |...|.|.||.|    |.|.    :|.|.........|:|.....||
Worm  8591 -SVDEKPK---------KKVLKKKTEKSD----SSIS----QKSDTAKTVAESAGQSDSETQKV- 8636

  Fly  3656 GLHEGKAYKFRVRAVNKEG-ESEDLETEKPIIAKNPYDEPDRPGKPEPTNWDKDFVDLAWDPPKN 3719
             ....||:|      .||. |.:.||:|  |.||.   ..::..|.|.....|..::
Worm  8637 -SEADKAHK------QKESDEKQKLESE--IAAKK---SAEQKSKLETEAKTKKVIE-------- 8681

  Fly  3720 DGGAPIQKYVIQMRDKSGRAWVDSATVPGDKCNGTVTGVEEGHEYEFRIVAVNKAGPSDPSDVSK 3784
            |..|..||   :..||  :...|||....|:        :|..:.|..  |.:|...|:.....|
Worm  8682 DESAKKQK---EQEDK--KKGDDSAKKQKDQ--------KEKQKLESE--ATSKKPTSEKQKDEK 8731

  Fly  3785 SVIAKPRFLKPHIDRKNLQKKIMRS-GQMLHIDALIKAEP-PAKVTWTYNKTEIKTSDHIKIENE 3847
            :         |....|:..:.:|.: .|.|.    :|:|| .:..|.|..| |:.:|..   :::
Worm  8732 T---------PQEKAKSENETVMTTEPQQLE----VKSEPKKSDKTETVEK-EVASSTE---KSD 8779

  Fly  3848 DYKTTFIMPKVKRADRGIYIVTAKNDS----------GSDTVEVELEVLCKPSKPKGPLAVSNV- 3901
            |.||.  .||.|:.     |:..|.|:          .||...::||       ....|::..|
Worm  8780 DSKTK--EPKEKKK-----IIKKKKDTTKPQEASKELSSDESRIDLE-------SDISLSLDTVT 8830

  Fly  3902 ------TAETLHLKWEKPEDDGGDPIEQYLVERMDTETGRWVPVLTTKTPEADVTGLTEGKEYLF 3960
                  ||.|  :|.:|..|:.|          :|:..|:
Worm  8831 ESDDLSTAST--IKLQKESDESG----------IDSRMGQ------------------------- 8858

  Fly  3961 RVKAVNSEGESEPLVTDIPTKAKNPFDAADTPGKPQI-VDWSGNHCDLKWRAPEDDGGASITGYI 4024
                 .||.|..|.::. |..|    ...:..|:.:. |.:|.....:||.  .||....:.
Worm  8859 -----TSEAEDSPFISQ-PVSA----TVTEMAGEAKFTVKFSRKPIYVKWM--RDDREIRVA--- 8908

  Fly  4025 VERKDPNTGKWQKALETSTPDCKARVNDLIAGNKYQFRIMAVNKAGKSKPSEPSDQMTAKDRFAP 4089
                      :.||...:|.|....|...|.| |....|.||      ..||....|...|...|
Worm  8909 ----------YGKASVETTDDSSVLVIKNIDG-KDVGNIYAV------FDSEYRSAMARLDLRVP 8956

  Fly  4090 PKI---DRTNIKDITIKAGQHIRFDIKVSGEPPATKV-WLHNKARLEN-------DDSNYNIDME 4143
            .||   ..:|..:|.  ||:::....|:||.|..|.: .|||...|..       |||   |.:.
Worm  8957 CKITLESSSNAPEIV--AGKNLDLSFKISGYPLPTNIELLHNNENLRTRSDVTDFDDS---ISIR 9016

  Fly  4144 SYRTKLTVPISKRFHSGKYTLKAENESGRDEASFEVIVLDKPGPPEGPLRVTDVHKEGCKLKWNA 4208
            ..|.||.       .||:..:..:|:|..|:....:.|::....|.. |:||...:|...|.|:.
Worm  9017 MKRLKLE-------DSGEIKIIGKNDSSEDQLRIPINVIEVTSKPTS-LQVTSTERETVTLTWSL 9073

  Fly  4209 PLDDGGLPIDHYIIEKMDVESGRWLPSGRFKESFAELNNLEPSHEYKFRVLAVNTEGESEPL-TG 4272
            |.:..|..::.|::|:..|:.|||..:....:|.|.::.|....||.|||:|||..|:|.|. |.
Worm  9074 PTELNGSNVNEYLVERKTVDGGRWRHACTVTDSRAVVDGLFSGTEYVFRVVAVNGAGQSAPSDTI 9138

  Fly  4273 EQSVIAKNPFDE--PGKP----GTPEAVDWDK--DHVDLVWRPPINDGGSPITGYVVEKREKGTD 4329
            |.:..|:...||  |..|    ..||:.|.||  |.||          .|.:   :.||::.|.|
Worm  9139 EATTQAEEEIDETVPTSPVEKVKEPESRDDDKSVDEVD----------DSTV---LEEKKDDGDD 9190

  Fly  4330 KWIKGTEITI------PCLGEECKATVPTLNENCEYEFRVKAINAAGPGEPSDASKPI-ITKPRK 4387
            |....|:..|      | ..|:..|..|...:..|.:.:..|....|..:..||.||. ::|.:|
Worm  9191 KSKPKTKKKIIKKKETP-ESEQVTAAEPEQQKISEVDVQSVAETEVGAKKKPDAEKPTDLSKAKK 9254

  Fly  4388 LAPKIDRKNIRTYNFKSGEPIFLDINISGEPAPDVTWNQNNKSVQTTSFSHIENLPYNTKYINNN 4452
                 |.|     :.||.||                 ..:.:...||      ..|.|.|....:
Worm  9255 -----DSK-----SKKSDEP-----------------EASTEEKSTT------EKPTNDKTSKKS 9286

  Fly  4453 PERKDTGLYKISAHNFYGQDQVEFQINIITKPGKPEGPLEVSEVHKDGCKLKWKKP---KDDGGE 4514
            .|:|                        ..||.|     ||:     |..|:.|||   |.|..:
Worm  9287 AEKK------------------------TVKPKK-----EVT-----GKPLEAKKPVEDKKDASQ 9317

  Fly  4515 PVESYLVEKFDPDTG---------IWLP---VGRSDGP-----EYNVDGLVPGHDYKFRVKAVNK 4562
            |..|  .|...|..|         :::|   ..|...|     |.|:...:.|.:
Worm  9318 PSSS--KESSPPTDGKKKKQIPKALFIPDEISSRFGDPSTMHSETNITTTIRGRE---------- 9370

  Fly  4563 EGESEPLETLGSIIAKDPFSVPTKPGVPEPTDWTANKVELAW------PEPAS---DGGSPIQGY 4618
                      ||..||.|...|....|....:....|.|.::      |:..|   :|..|.:.
Worm  9371 ----------GSADAKTPLVEPLSASVSMKVESAKEKAEFSFKRRSETPDDKSRKKEGLPPAKK- 9424

  Fly  4619 IVEVKDKYSPLWEKALETNSPTPTATVQGLIEGNEYQFRVVALNKGGLSE--PSDPSKIFTAKPR 4681
             .|.||:.:.  ||          .:.:.|||..:.:     :::..:||  |||.:|
Worm  9425 -SEKKDEVTA--EK----------QSTEALIESKKKE-----VDESKISEQQPSDKNK------- 9464

  Fly  4682 YLAPKIDRRNLRNITLSSGTALKLDANITGEP----APKVEWKLSNYHLQSGKNVTIETPDYYTK 4742
                                     :.:.|.|    .|:.:..:|...         |.|.  .|
Worm  9465 -------------------------SEVVGVPEKAAGPETKKDVSEIE---------EVPK--KK 9493

  Fly  4743 LVIRPTQRSDSGEYLVTATNTSGKDSVLVNVVITDKPSPPNGPLQISDVHKEGCHLKWKRPSDDG 4807
            .:.:.|::|||        :.|.|.:||       ||:..:                 |..|||
Worm  9494 TIKKKTEKSDS--------SISQKSNVL-------KPADDD-----------------KSKSDD- 9525

  Fly  4808 GTPIEYFQIDKLEPETGCWIPSCRSTEPQVDVTGLSPGNEYKFRVSAVNAEGESQPLVGDESIVA 4872
                   ..||          |.::||.|..|     ..:.|...:|     ::...:..|::|
Worm  9526 -------VTDK----------SKKTTEDQTKV-----ATDSKLEKAA-----DTTKQIETETVV- 9562

  Fly  4873 RNPFDEPGKPENLKATDWDKDHV--DLAWTPPLIDGGSPISCYI-----IEKQDKYGKWERALDV 4930
                |:..|.:.||......|..  ..:.|||:::...|.....     :.|..|..:.:..|..
Worm  9563 ----DDKSKKKVLKKKTEKSDSFISQKSETPPVVEPTKPAESEAQKIAEVNKAKKQKEVDDNLKR 9623

  Fly  4931 PADQCKATIPD---LVEGQTYKFRVSAVNAAGTGEPSDSTPPIIAKARNKPPIIDRSSLVEVRIK 4992
            .|:.....|.|   .:|.:....:.:.|.||...:..|.      :.:.:..::.:.|
Worm  9624 EAEVAAKKIADEKLKIEAEANIKKTAEVEAAKKQKEKDE------QLKLETEVVSKKS------- 9675

  Fly  4993 AGQSFTFDCKVSGEPAPQTKWLLKKKEVYSKDNVKVTNVDYNTKLKV--NSATRSDSGIYTVFAE 5055
            |.:....:.:...:.|.:...:.|:||:..|:.::........|||:  .||.:|..    |..|
Worm  9676 AAEKLELEKQAQIKKAAEADAVKKQKELNEKNKLEAAKKSAADKLKLEEESAAKSKK----VSEE 9736

  Fly  5056 NAN-GEDSADVKVTVIDKPAPPNGPLKVDEINSESCTLHWNPPDDDGGQPIDNYVVEKLDETTGR 5119
            :.. ||:    |.|...:        |..::.||               |.....::..|  .|.
Worm  9737 SVKFGEE----KKTKAGE--------KTVQVESE---------------PTSKKTIDTKD--VGA 9772

  Fly  5120 WIPAGETDGPVTALKVGGLTPGHKYKFRVRAKNRQGTS----EPLTTAQAIIAKNPFDVPTKPG- 5179
            ..||.|             ||..|.   ::.|..:..|    :..|.::.:..:...|.||||.
Worm  9773 TEPADE-------------TPKKKI---IKKKTEKSDSSISQKSATDSEKVSKQKEQDEPTKPAV 9821

  Fly  5180 --TPTIKDFDKEFVDLEW-------------TRPEADGGSPITGYVVEKRDKFSPDWEKCAEISD 5229
              |..:.:.||.....|.             |:.|||..|.:...            ||..::|:
Worm  9822 SETQMVTEADKSKKQKETDEKLKLDAEIAAKTKQEADEKSKLDAQ------------EKIKKVSE 9874

  Fly  5230 DITNAHVPDLIEGLKYE------------------------FRVRAVNKAGPGSPSDATETHVAR 5270
            |.......:|.:.||.|                        ..|.|..|..........:|..|.
Worm  9875 DDAARKEKELNDKLKLESEIATKKASADKLKLEEQAQAKKAAEVEAAKKQKEKDEQLKLDTEAAS 9939

  Fly  5271 PKNTPPKIDRNFMSDIKIKAGNVFEFDVPVTGEPLPSKDWTHEGNMIINTDRVKI---------- 5325
            .|....|::....:.||..||    .|.....:.|..|: ..|.|......::||
Worm  9940 KKAAAEKLELEKQAQIKKAAG----ADAVKKQKELDEKN-KLEANKKSAAGKLKIEEESAAKSKQ 9999

Fly 5326 -----SNFDDRTKIRILDAKRSDTGVYTLTARNINGTDRHNVKVTILDAPSVPEGPLRNGDVSKN 5385
:..|.:||.:..:.: |...::...|.....|.|:.:.| .
Worm 10000 TVEEQAKLDAQTKAKTAEKQ-------TKLEKDEKSTKESESKETVDEKP--------------K 10043

Fly 5386 SIVLRWRPPKDDGG----SEITHYVVEKMDNEAMRWVPVGDC------TD--------------- 5425
..||:.:..|.|.. ||.:..|||...........|.|. ||
Worm 10044 KKVLKKKTEKSDSSISQKSETSKTVVESAGPSESETQKVADAARKQKETDEKQKLEAEITAKKSA 10108

Fly 5426 ---TEIRADNLIENHDYSFRVRAVNKQGQ-SQPLTTSQPITAK---------DPYSHPDKPGQPQ 5477
:::.|::.::. :..|.|..||.: .:.|.......:| :..||..|..:..
Worm 10109 DEKSKLEAESKLKK---AAEVEAAKKQKEKDEQLKLDTEAASKKAAAEKLELEKQSHIKKAAEVD 10170

Fly 5478 ATDWGKHF-----VDLEWSTPKRDG-----------GAPISSYIIEK-RPKFGQWERAAVVLGDN 5525
|....|.. ::.|.:|.|.|. .|.|:...|:| :.|..|.:.. |.|.
Worm 10171 AVKKQKELEEKQRLESEAATKKADAEKLKLEEQKKKAAEIALIEIQKEQEKLAQEQSR---LEDE 10232

Fly 5526 CKAHVPELTNGGEYEFRVIAVNRGGPSDPSDPSSTIICKPRFLAPFFDKSLLNDITVHAGKRLGW 5590
.|... |.:.:............|..::..||: |.:|...|
Worm 10233 AKKSA---------EKQKLESETKSKQTEEAPKESVDEKPK-------KKVLKKKT--------- 10272

Fly 5591 TLPIEASPRPLITWLYNGKEIGSNSRGESGLFQN----ELTFEIVSSLRSDEGRYTLILKNE--- 5648
.:.:|.:.|. :.|.:...:|.|| :.|:.|..
Worm 10273 ------------------------EKSDSSISQKSKSAKSTVDAAETLESD---FNLVEKKTVQK 10310

Fly 5649 -HGSFDASAHATVLDRPSPPKGPL------DITKITRDGCHLTWNVPDDDGGSPILHYIIEKMDL 5706
..|.|.|..||:...|:.....: |..|.|.|| ....|:|...:|....:.:|...
Worm 10311 VEQSPDESTSATIKRDPAQKTEEISKQDDGDEKKTTTDG---KPPKPEDSEATPKKRVVKKKTQK 10372

Fly 5707 SRSTWSDAGMSTHIVHDVTRLVH------RKEYLFR--VKAVNAIGESD------------PLEA 5751
|.|..|||.:: ||::|.. :|:.|.: .|:.:.|.|:. |.|.
Worm 10373 SDSVASDASLA-----DVSKLSDDVEEKPKKKVLKKKTEKSDSVISETSSVDTIKPESVEIPTEK 10432

Fly 5752 VNTIIAKNEFDEPDA----PGKPIITDWDRDHIDLQWAVPKSDGGAPISEYIIQKKEKGSPYWTN 5812
...:|..|.|....| |......|.::...|: ..:.|.|..:::
Worm 10433 AEQMILHNRFSTDSAVESEPKNAHKDDTEKTTDDM------------------MTRRKSSAIFSD 10479

Fly 5813 VRHVPSNKNTTTIPELTEGQEYEFRVIAVNQAGQSEPSEPSDMIMAKPRYLPPKIITPLNEVRIK 5877
.....|:|.: :||:....|....::.. ||.:..:. :.|.|:
Worm 10480 DEQSISSKTS------SEGRRRRRRTGFASKFA-------SDTLALRG-----------DNVEIE 10520

Fly 5878 CGLIFHTDIHFIGEPAPEATWTLNSNPLLSNDRSTITSIGHHSVVHTVNCQRSDSGIYHLLLRNS 5942
..|:...| ..||.:|......|.|. |.:.||.
Worm 10521 AELLAEDD---------TVTWKVNGKDADLNSRC-------HEMSHTF----------------- 10552

Fly 5943 SGIDEGSFELVVLDRPGPPEGPMEYEEITANSVTISWKPPKDNGGSEISSYVIEKRDLTHGGGWV 6007
|..:::|...|.:..| ||||.. |:|..:.:::..:|
Worm 10553 -------FRTLIIDEVEPTDSGM---EITATC------------GTESHTTILKVEEL------- 10588

Fly 6008 PAVNYVSAKYNHAVVPRLLEGTMYELRVMAENLQGRSDPLTSDQPVVAKSQYTVPGAPGKPELTD 6072
.|::| || :||...|. :|: |:|
Worm 10589 -PVDFV--KY----LPRKTSGK-----------EGQ-------------------------EVT- 10609

Fly 6073 SDKNHITIKWKQPISNGGSPIIGYDIERRDVNTGRWIKINGQPVP-TAEYQDDRVTSNHQYQYRI 6136
|::....|| |::...|:| :|:|:. ..:|..|.|..:.....|.
Worm 10610 -----ISVTLNHPI---------------DISKVVWLK-DGKPLEINKDYSIDTVGCSVSLTLRR 10653

Fly 6137 SAVNAAGNGKTSEPSAIFNARPLREKPRFYFDGL-IGKRIKVRAGEPVNLNIPISGAPTPTIEWK 6200
:....:| |.:...||: ....:.:: |:||..|: ....|.|...
Worm 10654 AKYEDSG------------------KYKVVCDGVDCSTHLSIQ-GKPVLKNV---SETKPVITVD 10696

Fly 6201 RGDLKLEEGKRISYETNSERTLFR-----------------IDDS--------NRRDSGKYTVTA 6240
:.| :....::|::|.|.:... :||. ::.|:|:|.|..
Worm 10697 KDD---QFSLLVAYDSNPEASFSMTVDGKDLEFDGRSRIDVVDDGLKLTKRGVSKTDAGEYEVKL 10758

Fly 6241 ANEFGKDTADIEVIVVDKPSPPEGPLSYTETAPDHISLHWYSPKDDGGSDITGYIIEFTEFGVDD 6305
.||||:.....:|.|.|.||.| |.:|..:...|.:.:.|.:|.:|.|:::|.|:||..|.|...
Worm 10759 KNEFGEVAQKFDVKVNDTPSAP-GDVSVVKAESDCLHIEWTAPTEDNGAEVTSYVIEKKESGRRK 10822

Fly 6306 W-KPVPGTCPNTNFTVKNLVEGKKYVFRIRAENIYGASEALEGKPVLAKSPFDPPGAPSQPTISA 6369
: |........|::.|.:|.....|:.||.|.|.:|..|.:|.|||...|||..|.....|||..
Worm 10823 FHKVATVNGKKTSYVVDDLEIETPYIVRIAAVNKFGTGEFIETKPVQTGSPFQVPTVEFPPTIDN 10887

Fly 6370 YTPNSANLEWHPPDDCGGKPITGYIVERRERGGEWIKCNNYPTPNT-SYTVSNLRDGARYEFRVL 6433
.|..|.:|.|..|.:.||.|:.||.|.:||..|||.|.|......| |:.|..|..|..|||::.
Worm 10888 VTSTSCSLSWPKPIEDGGSPVYGYDVYKRENEGEWQKMNGEELVFTESFNVRALSSGKEYEFKIE 10952

Fly 6434 AVNEAG-PGHPSKPSDPMTAEHQRYRPDPPE----PPKPDRITRNGVTLSWRPPRTDGKSRIKGY 6493
|.|||| ..:.:..|..:|.|.. .|| .|....:..:.|.::| ::||: |.:
Worm 10953 ACNEAGLRSNSNVVSKKLTVEGL-----VPEIILDMPMVKVLDNDKVEVTW---KSDGE---KEF 11006

Fly 6494 YVEMRPKNGKDWKTVNDI--PINSTVYT----VPSLKEGEEYSFRVVAENEVGRSDPSKPSQPIT 6552
.|:.:......|.:| || |.:.:..| :..|:||..|.|||.|.|:.|..:.|:|:.|:.
Worm 11007 VVQYKSDGSSIWASV-DIGGPRSESAATSKCIIDGLREGIPYVFRVAARNQHGTGEFSEPTIPVV 11070

Fly 6553 I--EEQPN-----KPCM--ELGKVRDIVCRAGDDFSIHVPYLAFPKPNAFWYSNDNML---DDNN 6605
: ::.|. ||.. :.|::| :.|.|. ..|.|...||.:...: |:|.
Worm 11071 VLADDAPRVLKAIKPVKIPKKGELR-LECHAA----------GHPAPEYIWYKDGKEIIPTDENT 11124

Fly 6606 RVHKHLTDDAASVVVKNSKRADSGQYRLQLKNTSGFDTATINVRVLDRPSPPTRLRA---DEFS- 6666
.:... ...:::::......|.|.|::.::|..|...:...|.:.| :|| ..||
Worm 11125 EIVNE--GSMSALIIHELAGEDVGLYKVLVENIHGTAESEAEVGISD-------VRAHFNSSFSE 11180

Fly 6667 ------GDSLTLYWNPPNDDGGSAIQNYIIEKKEARSSTWSKVSSFCTVPFVRIRNLVLNKEYDF 6725
|..:.|.....::: |:.|:..:.|:..:|...:..:......:||:. :.:.|.
Worm 11181 LTEIEEGHDIELTCEVSDEE---AVVNWYKDGKKLVASDRVQFYAMARKRTLRIKG---STDADS 11239

Fly 6726 RVI-AENKYGQSDPANTSEPILARHPFDIPNTPGIPHGIDSTEDSITIAWTKPKHDGGSPITGYI 6789
.|. .|...|:| .|...::.... .||.:...:|:|. .|.|..:..:.
Worm 11240 GVYKCETTDGRS---RTEGEVIVNEQ--------EPHILVGPQDAIV-------KDFGETMVLFC 11286

Fly 6790 IEKRLLSDDKWTKAVHALCPDLSCKIPNLIEN----AEYEFR------VAAVNAA-GQSAYSGSS 6843
...:.:...||.|....:.|.::..| :|| |..|.: :.|..|: .:...|..:
Worm 11287 ETSKPVRKVKWFKNGVEIWPQMNKAI---MENDGKRATLEIKNFDKHDIGAYTASVSEKETSAPA 11348

Fly 6844 DLIFCRRPPHAPKITSDLSIRD-MTVIAGDEFRITVPYHASPRPTASWSLNG--LEVIPGERIKF 6905
.|:| ..||.:.....||| :||.||:||...|.:...|.||...:.|| |:.| .:..
Worm 11349 KLVF----EVAPNLIIPTEIRDGVTVHAGNEFDFAVEFSGFPIPTIHLTNNGTPLKAI---AVVT 11406

Fly 6906 DSNDYASMYYNKSAKRDETGSYTITLTNNKGSDTASCHVTVVDRPLPPQGPLNAYDITPDTCTLA 6970
:.:|..|:.. |....|.:|:..:...:..|.......:.::|:|..| ..|...::|.|:..|:
Worm 11407 EYDDSVSVRM-KDVTLDNSGTVRVIAESPLGQCIKEIPLKIIDKPSAP-CDLQFKEVTEDSVFLS 11469

Fly 6971 WKTPLDDGGSPITNYVVEK--LDNSGSW-----VKIS--SFVRNTHYDVMGLEPHYKYNFRVRAE 7026
|:.||:..|:|:|.||:|: :||: .| ||.: :||.. .|..:..|.||:.|.
Worm 11470 WQPPLETNGAPLTGYVIERKAVDNN-RWRPCGQVKPTKLTFVAE------DLFCNQVYGFRILAV 11527

Fly 7027 NQYGLSDPLDII--------EPIVAKHQFTVPDEP--GQPKV-IDWDSGNVTLIWTRPLSDGGSR 7080
|:.|.|:|.|.: ||:....:..||... ..|:| :..|...|||.| :....
Worm 11528 NEVGESEPCDTVDVLTLESSEPVSESSELFVPKIAILRTPQVTVAVDETKVTLRW-----EECPE 11587

Fly 7081 IQGYQIEYRDILNDSSWNAYDYIIKDT---KYQLYNLINGSEYEFRIKAKNAAGLSKPSSPSLRF 7142
...|::| |..:.||.| ..|.:| |::..:|....||.:::.|.....:|.||..:...
Worm 11588 TSLYKVE-RKKVGDSDW----LEIANTDRNKFKDRSLTESGEYVYQVTATGIHAVSSPSEETNPV 11647

Fly 7143 KLKGKFTVPSP--PGAPQVTRVG--------KNYVDLKWEKPL-RDGGSRITGYIIERRDIGGAV 7196
|: .||.. |.:....:.. |:..::..||.: :...|..|...:|.:.....|
Worm 11648 KI----LVPGSEMPASKTEKKTDAAKSESEQKSAEEIVAEKQVDQSQASESTTEAVEEKKTKKVV 11708

Fly 7197 WVKCNDYNVLDTEYTVMNLIEMGDYEFRV-----------------FAVNSAGRSEPSLCTMPIK 7244
..|..:....:|...|...::.|....:| ....|..|||..|.....|
Worm 11709 KKKVAENKGEETLQEVKEKLKKGKAVEKVQDESRRGSLQASSDNESVTTTSEKRSEAELEKNSEK 11773

Fly 7245 VCE-------------------VLGGKKPDWITRLQDKVAPFG----------------KDYTLQ 7274
..| ..|.:..:...::..|||..| .:.:.|
Worm 11774 SAEKKSTSADLEAADKAETEKSETGKETTEKKKKVVKKVAKKGLVKADKSKIELTAGKEGEISAQ 11838

Fly 7275 CAASGKPSPTARWLRNGKEIQMNGGRMTCDSKDGVFRLHISNVQTGDDGDYTCEAMNSLG---FV 7336
.|.:| .:..|.::||.:..: .|..|..||..:.|..|.....|.:||:..:|.| .|
Worm 11839 VAETG---VSVEWKKDGKALDAS---YTVTSTGGVSTVKIPIVDVNTSGVFTCKVKSSEGDEEEV 11897

Fly 7337 NTSGYLKIGSPPIINRCPSELKLPEGDNSKIKIFYSGDQPLTVILKKNNEVICDSNDDTHVKVNI 7401
:.:..:|:...|.:....|.:::..||.:|:....| :...:|...|:::.| .:|.:||..:
Worm 11898 SIAVTVKLPEVPKVEAEQSIVEVKVGDVAKLSAKIS-EPASSVNWTKDDKPI---KEDGNVKAQL 11958

Fly 7402 FDDYVA-IYIRNIVKSDGGPYQIEFTNESGSATGEFYVHI----TGMPSAPTGPMGISYINKNSC 7461
..|..| :.|.....:..|.|::...|::|....|..:.| .|.|..||||:....:.::|.
Worm 11959 SPDGTAQLTISKTDSAHSGIYKLNVENDAGKGKVEIALRIKGAAKGAPGIPTGPIVFDDVTESSA 12023

Fly 7462 MLNWRPPSYDGGLKVSHYVIERKDVSSPHWITVSSTCKDTAFNVQGLIENQEYIFRVMAVNENGM 7526
..:|:.|..:||.:::.|.:|||:..:..|.....| |:..|...||.|..:|..:|.|||..|.
Worm 12024 EFSWKAPENNGGCEITGYNVERKESKNKGWKQCGKT-KELKFKADGLEEGTDYDVKVSAVNTMGT 12087

Fly 7527 GPPLEG-LNPIRAK--------------------DPIDPPSPPGSPQITEIGGDFVHLEWEKPES 7570
|..||| :..::.| |.:......|.|:........:.|:|.....
Worm 12088 GSALEGKITTLKKKEETGKQKSEKSESDEKKSESDKVSELKQIGKPEYVSSTATSIALKWTSDND 12152

Fly 7571 DGGAHIQGYWIDKREVGS-NTWQRVNATI--CAANQINCINLIEGRQYEFRIFAQNVAGLSTESS 7632
: ..|.:..:|..| ..|..|...| |:| ....|.||..|.||:.|||..|.:..|.
Worm 12153 E-----VTYTVQMKEANSKRPWAVVAKEISECSA---TIAQLKEGTSYLFRVIAQNKTGQTVTSE 12209

Fly 7633 ASQAVKIIDPQAASPPLIVKPLRDANCIQNHNAQFTCTINGVPKPTISWYKGAREISNGARYHMY 7697
.|::::..|...:..|.......|...::|...:.|....|.|.|.|.|:|..:||.:|.|..:.
Worm 12210 QSESIECKDTTESKKPAFTNAPTDLTAVKNGKTKITAEFTGHPAPEIHWFKNKKEIFSGKRQWIE 12274

Fly 7698 SEGDNHFLNINDVFGEDADEYVCRAVNKAGAKSTRATLAIMTAPKLNVPPRFRDTAYFDKGENVV 7762
:......|.|.::..:|..||.....|.||:......|.:...|::|...|:..|..|||||.|.
Worm 12275 NIAGATSLTIGEMREDDEGEYKIVVKNTAGSVEHSCKLTMDQLPEINRVDRYASTLVFDKGETVK 12339

Fly 7763 IKIPFTGFPKPRIHWV-RDGENIESGGHYTVEVKERHAVLIIRDGSHLDSGPYRITAENELGSDT 7826
:::.|:|.|:|.:.|: .:|:.||......:|....:.||.|......|.|.:.:..:|..|.|.
Worm 12340 LRLSFSGRPQPEVIWIDNNGKVIEESRKMKIEKTVLNTVLTINSIDSQDQGEFALKIKNRCGEDK 12404

Fly 7827 AIIQVQISDRPDPPRFPLIESIGTESLSLSWKAPVWDGCSDITNYYVERREHPLSSWIRVGNTRF 7891
..|.:|::|||..|..|.:|....:|:.|.|.||..||.|.:.||.||.......:|.:...|:.
Worm 12405 YAIGIQVTDRPAAPGKPAVEDQNVDSVRLRWAAPTNDGGSPVRNYTVEMCTEKGKTWTKAEVTKQ 12469

Fly 7892 TSMAVSGLTPGKEYDFRIFADNVYGRSDASDTSTLIKTK------ESVKKKPIERKWEIDANGRK 7950
..:.:..|.||:.|.||:.|||.:|:|:.||.|.|:..| |..|||.::.|.:...:..:
Worm 12470 AFITLFNLVPGESYRFRVRADNTFGQSEPSDESELVVVKNVSRVVEEPKKKEVKVKEQESVDYER 12534

Fly 7951 LRGKADGPVKDYDSYVFDIYSKFVPQPVEISQQSVYDRYDILEEIGTGAFGVVHRCRERSTGNIF 8015
: ..|....:|.: .||:. :|..::. :|.|.||:|.||:|.|:|..|::||..:
Worm 12535 V--AKDSEPSEYKT--IDIHR--LPNDLQA-------KYIIHEELGKGAYGTVYRATEKATGKTW 12586

Fly 8016 AAKFIPVSHSVEKDLIRREIDIMNQLHHQKLINLHDAFEDDDEMILILEFLSGGELFERITAEGY 8080
|||.:.|...|:|:.:..||.:||||||:||:|||:||:..:||.||.||:|||||||:|..:..
Worm 12587 AAKMVQVRPGVKKENVIHEISMMNQLHHEKLLNLHEAFDMGNEMWLIEEFVSGGELFEKILEDDS 12651

Fly 8081 VMTEAEVINYMRQICEGIRHMHEQNIIHLDIKPENIMCQTRSSTNVKLIDFGLATRLDPNEVVKI 8145
:|:|.||.:||.||..|:.|||:..|:|||:|||||:.:.::|..:|:||||||.:|||.:.||:
Worm 12652 LMSEEEVRDYMHQILLGVSHMHKNQIVHLDLKPENILLKAKNSNELKIIDFGLARKLDPKKSVKL 12716

Fly 8146 TTGTAEFAAPEIVNREPVGFYTDMWATGVLSYVLLSGLSPFAGDNDVQTLKNVKACDWDFDVESF 8210
..||.||.|||:||.:|||..||||..||:|||||||||||.||:|..||.||.|.|||||..|:
Worm 12717 LFGTPEFCAPEVVNYQPVGLSTDMWTVGVISYVLLSGLSPFLGDSDEDTLANVSASDWDFDDPSW 12781

Fly 8211 KYISEEAKDFIRKLLVRNKEKRMTAHECLLHPWLTG-------DHS----AMKQEINRDRYLAYR 8264
..:|:.|||||.:|::::|.|||:..:.|.|||:|| |.| .|:.::::....|.:
Worm 12782 DDVSDLAKDFICRLMIKDKRKRMSVQDALRHPWITGPLLSAFNDLSEYVKKMQPKLDKSGVPARQ 12846

Fly 8265 EK----LRRKYEDFERFLLPIGRLSEYSSL-RKLLMEKYKIHDAVFDRR-----QAAP------- 8312
:: |:|..:| |||||||::..:: |:|.| |.||:|. .|||
Worm 12847 KRNFLSLKRWSDD----LLPIGRLAKRGAIFRRLTM------DGVFERNIAFDTDAAPSVKKQLE 12901

Fly 8313 -------------------------------RFVIRPSSQF---------------CYEGQSVKF 8331
:.:..||.:: ..|..:.|:
Worm 12902 DIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKY 12966

Fly 8332 YCRC------------------------------------------------------------- 8335
.||.
Worm 12967 TCRATNDLGSIMTHAKLSVKADEKKKKKSKTSPAVIEKKKDRKTSKVVVIEEMIDMPPNFHHLLQ 13031

Fly 8336 ----------IAIAT------PTLTWSHN--NIELRQSVKFMKRYVGDDYYFIINRVKLDDRGEY 8382
|.:.| ||:.|.|| :|.:..| .:::::....|...|..|...|.|::
Worm 13032 DDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISINDS-NYLRKHDKGRYELHILSVDSTDEGKW 13095

Fly 8383 IIRAENHYGSREEVVFLNVQPLPKEQ--PRYRTESTPVRRRE-------------PLPYTFW-QE 8431
....:|.:|..|....|.| .:|..| |.:..:.:.|:..| |.|...| :.
Worm 13096 KAVGKNAFGECESEAKLTV-VIPDGQYAPSFGKQLSDVKCSESDILKLEVNIQANPAPEINWFRN 13159

Fly 8432 ESE-------------------------------------------------------------- 8434
|||
Worm 13160 ESEIEHSQHHRLQFDDGSGNYSLTIIDAYAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKK 13224

Fly 8435 ----TAPSFTFLL-RPRVMQARDTCKLLCCLSGKPVPNVRWYKDGRELSKYEYAMTHSDGVVTME 8494
.||.|...| .||.:.......|:|.:||.|.||::|.||.:.:......:.|.:||.|:.
Worm 13225 IDGSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDDKPIDMSNKQVRHENGVCTLH 13289

Fly 8495 IIDCKPSDSGKYSCKATNCHGTDETDCVV----IVEGEWVTPEQAQ-LAHNFLYSGDRKYIEQPI 8554
||..:..|.|:|.|:|.|.||..::..|| .|:.:.|.|:..: |.:.....|:...:|..:
Worm 13290 IIGARDDDQGRYVCEAENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCV 13354

Fly 8555 KPAPLPIVT-SRQYTSSSVQNTSEPQGDKVNVSNSNSSGI--SNKKKYASNSLQAPG-------- 8608
...|:|.:| .:......::|......|:..||..|...: ::..:|...::.:.|
Worm 13355 TGKPIPTITWYKDGLKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTV 13419

Fly 8609 ----------------SPSRSRSATKELILPPDDSLMCKPEFTKPLHDLTIHDGEQLILTCYVKG 8657
|.|||||.:..:: ...:...|..|:||.|.|:.:|.:.:|...|.|
Worm 13420 KVVDMGLSKTRLTPVRSRSRSRSRSPSVV---GGEIQRPPVVTRPLADATVTEGNRELLEVEVDG 13481

Fly 8658 DPEPQISWSKNGKSLSSSDILDLRYKNGIATLTINEVFPEDEGVITCTATNSVGAVETKCKLTIQ 8722
.|.|.|.|..:||.::.|..|...:...:|.|.|.|...|..|...|..:|.:|||||:..:.::
Worm 13482 FPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVE 13546

Fly 8723 PLDKNINKRKVNAGDNA---PKIVSHLESRFVRD-GDAVNLACRIIGAQHFDVVWLHNNKEIKPS 8783
..| |.::. |..|..|:...::. |:.....|:........||||||.|.::.:
Worm 13547 APD---------AAEHVTQMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKALQQT 13602

Fly 8784 KDFQYTN--EANIYRLQIAEIFPEDGGTYTCEAFNDIGESFSTCTINVTVPGDETKQ-----PSF 8841
|....|. :.|...|.|..:..|..||||..|.|..|:..::. .:|:.|.|.|: |.|
Worm 13603 KSNYKTRLFDDNTATLVIENVTDELCGTYTAVANNQFGDVHTSA--QLTISGSEAKKIAASLPYF 13665

Fly 8842 -VKFPTSVSVLEGEGTTFECEID-SELLNLVWLKDGKPIDETLPRYSFTKDGHRYSFAVAKCNMD 8904
::....::|:||...:.:.::: |.:..:|||||...:.|: .|.....||..|...|....::
Worm 13666 IIELKPKINVVEGATLSIQADLNGSPIPEVVWLKDNSELVES-DRIQMKCDGVNYQLLVRDVGLE 13729

Fly 8905 DVGQYQAKAVSGKAE 8919
|.|.|...|.:.|.:
Worm 13730 DEGTYTITAENEKGK 13744

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bt	NP_001162825.1	I-set	9..101	CDD:254352	17/68 (25%)
		Ig	26..100	CDD:143165	17/67 (25%)
		I-set	119..210	CDD:254352	26/104 (25%)
		Ig	136..209	CDD:143165	22/86 (26%)
		I-set	228..320	CDD:254352	21/103 (20%)
		IGc2	242..312	CDD:197706	16/78 (21%)
		I-set	335..425	CDD:254352	16/117 (14%)
		Ig	350..423	CDD:143165	13/94 (14%)
		Ig	436..530	CDD:299845	16/97 (16%)
		I-set	438..532	CDD:254352	16/97 (16%)
		I-set	545..636	CDD:254352	23/90 (26%)
		Ig	560..633	CDD:143165	17/72 (24%)
		Ig	657..731	CDD:143165	17/85 (20%)
		I-set	746..835	CDD:254352	20/107 (19%)
		Ig	1496..1586	CDD:299845	13/105 (12%)
		IG_like	1503..1588	CDD:214653	12/96 (13%)
		I-set	1639..1724	CDD:254352	23/100 (23%)
		IG	1750..1821	CDD:214652	17/82 (21%)
		IGc2	1750..1806	CDD:197706	11/64 (17%)
		I-set	1826..1909	CDD:254352	14/83 (17%)
		Ig	1831..1897	CDD:299845	11/65 (17%)
		I-set	1914..1998	CDD:254352	23/99 (23%)
		Ig	2020..2095	CDD:299845	20/80 (25%)
		FN3	2100..2194	CDD:238020	23/126 (18%)
		FN3	2203..2292	CDD:238020	14/88 (16%)
		I-set	2311..2395	CDD:254352	21/83 (25%)
		Ig	2321..2395	CDD:299845	18/73 (25%)
		FN3	2399..2493	CDD:238020	30/96 (31%)
		FN3	2501..2590	CDD:238020	14/93 (15%)
		I-set	2602..2693	CDD:254352	17/97 (18%)
		Ig	2619..2693	CDD:299845	14/80 (18%)
		FN3	2697..2793	CDD:238020	25/130 (19%)
		FN3	2801..2893	CDD:238020	23/98 (23%)
		I-set	2902..2995	CDD:254352	22/113 (19%)
		Ig	2919..2993	CDD:299845	20/94 (21%)
		FN3	2999..3088	CDD:238020	14/88 (16%)
		FN3	3102..3191	CDD:238020	19/102 (19%)
		I-set	3208..3292	CDD:254352	18/87 (21%)
		Ig	3219..3292	CDD:299845	15/76 (20%)
		FN3	3296..3390	CDD:238020	21/100 (21%)
		FN3	3400..3489	CDD:238020	15/89 (17%)
		I-set	3494..3590	CDD:254352	12/95 (13%)
		Ig	3516..3590	CDD:299845	9/73 (12%)
		FN3	3594..3682	CDD:238020	25/88 (28%)
		FN3	3694..3781	CDD:238020	18/86 (21%)
		I-set	3795..3885	CDD:254352	25/101 (25%)
		Ig	3813..3885	CDD:299845	21/82 (26%)
		FN3	3889..3980	CDD:238020	15/97 (15%)
		FN3	3990..4082	CDD:238020	20/92 (22%)
		I-set	4090..4181	CDD:254352	27/101 (27%)
		Ig	4108..4181	CDD:299845	21/80 (26%)
		FN3	4185..4271	CDD:238020	29/86 (34%)
		FN3	4285..4383	CDD:238020	29/110 (26%)
		Ig	4404..4480	CDD:299845	10/75 (13%)
		FN3	4484..4571	CDD:238020	22/106 (21%)
		FN3	4584..4677	CDD:238020	22/103 (21%)
		I-set	4685..4775	CDD:254352	15/93 (16%)
		Ig	4703..4775	CDD:299845	15/75 (20%)
		FN3	4779..4863	CDD:238020	14/83 (17%)
		FN3	4879..4970	CDD:238020	19/100 (19%)
		IG	4989..5069	CDD:214652	17/82 (21%)
		Ig	4996..5069	CDD:299845	16/75 (21%)
		FN3	5073..5166	CDD:238020	15/96 (16%)
		FN3	5175..5265	CDD:238020	24/129 (19%)
I-set	5276..5366	CDD:254352	18/104 (17%)
Ig	5293..5366	CDD:299845	13/87 (15%)
FN3	5370..5462	CDD:238020	20/120 (17%)
FN3	5470..5561	CDD:238020	18/107 (17%)
Ig	5559..5654	CDD:299845	14/102 (14%)
I-set	5570..5660	CDD:254352	15/97 (15%)
FN3	5664..5755	CDD:238020	25/116 (22%)
FN3	5764..5853	CDD:238020	11/92 (12%)
I-set	5865..5954	CDD:254352	13/88 (15%)
Ig	5882..5954	CDD:299845	10/71 (14%)
FN3	5958..6049	CDD:238020	17/90 (19%)
FN3	6062..6153	CDD:238020	15/91 (16%)
I-set	6173..6255	CDD:254352	21/106 (20%)
Ig_Titin_like	6182..6255	CDD:143225	20/97 (21%)
FN3	6259..6350	CDD:238020	29/91 (32%)
FN3	6359..6451	CDD:238020	36/93 (39%)
FN3	6470..6552	CDD:238020	25/87 (29%)
I-set	6564..6650	CDD:254352	16/88 (18%)
Ig_Titin_like	6577..6650	CDD:143225	12/75 (16%)
FN3	6654..6745	CDD:238020	18/101 (18%)
FN3	6754..6840	CDD:238020	17/96 (18%)
I-set	6855..6946	CDD:254352	24/93 (26%)
Ig	6874..6946	CDD:299845	15/73 (21%)
FN3	6950..7042	CDD:238020	34/108 (31%)
FN3	7050..7139	CDD:238020	24/94 (26%)
FN3	7151..7237	CDD:238020	18/113 (16%)
I-set	7254..7334	CDD:254352	20/95 (21%)
Ig	7272..7339	CDD:143165	18/69 (26%)
IG_like	7354..7440	CDD:214653	19/86 (22%)
Ig	7366..7440	CDD:299845	16/74 (22%)
FN3	7444..7531	CDD:238020	28/86 (33%)
FN3	7545..7637	CDD:238020	24/94 (26%)
I-set	7648..7737	CDD:254352	23/88 (26%)
Ig	7665..7734	CDD:143165	19/68 (28%)
Ig	7760..7833	CDD:299845	19/73 (26%)
FN3	7837..7927	CDD:238020	32/89 (36%)
STKc_Twitchin_like	7986..8244	CDD:271016	139/257 (54%)
S_TKc	7989..8244	CDD:214567	139/254 (55%)
Ig	8311..8394	CDD:299845	24/214 (11%)
I-set	8312..8401	CDD:254352	25/220 (11%)
I-set	8437..8525	CDD:254352	31/92 (34%)
Ig	8455..8519	CDD:143165	24/63 (38%)
I-set	8632..8721	CDD:254352	31/88 (35%)
IGc2	8646..8711	CDD:197706	20/64 (31%)
I-set	8740..8831	CDD:254352	25/93 (27%)
Ig	8757..8826	CDD:143165	21/70 (30%)
I-set	8839..8922	CDD:254352	22/83 (27%)
Ig	8845..>8909	CDD:299845	17/64 (27%)
ttn-1	NP_001346715.1	IG	105..177	CDD:214652
		I-set	205..285	CDD:333254
		I-set	406..493	CDD:333254
		I-set	821..914	CDD:333254
		Ig	962..1032	CDD:319273
		I-set	1135..1215	CDD:333254
		I-set	1679..1767	CDD:254352
		Ig	1789..>1845	CDD:319273
		Atrophin-1	<1957..2285	CDD:331285
		I-set	2381..2468	CDD:333254
		I-set	2489..2578	CDD:333254
		I-set	2631..2717	CDD:333254
		I-set	2732..2815	CDD:333254
		Ig	2848..2909	CDD:319273
		I-set	2924..3007	CDD:333254
		RNase_E_G	<3161..3303	CDD:331378
		RNase_E_G	<3356..3556	CDD:331378
		RNase_E_G	<3506..3673	CDD:331378
		RNase_E_G	<3595..3803	CDD:331378
		RNase_E_G	<3722..3912	CDD:331378
		RNase_E_G	<3875..4073	CDD:331378
		FtsK	<4014..>4556	CDD:332908
		RNase_E_G	<4346..4567	CDD:331378
		RNase_E_G	<4525..4723	CDD:331378
		RNase_E_G	<4746..4936	CDD:331378
		RNase_E_G	<4858..5044	CDD:331378
		FtsK	<4960..>5541	CDD:332908	84/406 (21%)
		Neuromodulin_N	<5525..6250	CDD:331332	162/793 (20%)
		Neuromodulin_N	<6198..6681	CDD:331332	117/544 (22%)
		V-ATPase_G_2	<6559..>6683	CDD:330366	19/148 (13%)
		I-set	7448..7535	CDD:333254	23/89 (26%)
		FN3	7540..7630	CDD:238020	31/100 (31%)
		MDN1	<7687..8197	CDD:331582	110/568 (19%)
		Neuromodulin_N	<7944..8780	CDD:331332	214/1083 (20%)
		Ig	8886..>8935	CDD:325142	14/64 (22%)
		FN3	9052..9142	CDD:238020	31/90 (34%)
		Neuromodulin_N	<9210..9875	CDD:331332	178/954 (19%)
		Neuromodulin_N	<9583..10392	CDD:331332	173/974 (18%)
		IG_like	10597..>10662	CDD:214653	19/140 (14%)
		Ig	10711..10773	CDD:325142	12/61 (20%)
		FN3	10777..10870	CDD:238020	31/93 (33%)
		FN3	10883..10958	CDD:238020	32/74 (43%)
		FN3	10984..11070	CDD:238020	26/92 (28%)
		I-set	11077..11165	CDD:333254	18/100 (18%)
		IG	11179..11259	CDD:214652	15/88 (17%)
		I-set	11264..11350	CDD:333254	18/95 (19%)
		I-set	11368..11446	CDD:333254	20/81 (25%)
		FN3	11450..11543	CDD:238020	32/100 (32%)
		FN3	11565..11645	CDD:238020	23/89 (26%)
		I-set	11823..11903	CDD:333254	18/85 (21%)
		I-set	11918..11996	CDD:333254	18/81 (22%)
		FN3	12006..12097	CDD:238020	31/91 (34%)
		FN3	12131..12217	CDD:238020	24/93 (26%)
		I-set	12225..12313	CDD:333254	22/87 (25%)
		Ig	12337..12411	CDD:325142	19/73 (26%)
		FN3	12415..12503	CDD:238020	31/87 (36%)
		PKc_like	12566..12815	CDD:328722	135/248 (54%)
		I-set	12894..12985	CDD:254352	7/90 (8%)
		I-set	13024..13114	CDD:333254	18/90 (20%)
		I-set	13123..13206	CDD:254352	9/82 (11%)
		Ig	13249..13314	CDD:319273	24/64 (38%)
		I-set	13331..13421	CDD:254352	14/89 (16%)
		I-set	13456..13545	CDD:254352	31/88 (35%)
		I-set	13558..13650	CDD:254352	25/93 (27%)
I-set	13663..13753	CDD:254352	22/83 (27%)
FN3	13778..13864	CDD:238020
Ig	13893..13963	CDD:325142
I-set	13984..14074	CDD:333254
I-set	14083..14168	CDD:254352
Ig_3	14195..14275	CDD:316449
Ig_3	14302..14384	CDD:316449
I-set	14408..14498	CDD:333254
I-set	14634..14724	CDD:333254
IG_like	14754..14838	CDD:214653
I-set	14854..14943	CDD:333254
I-set	14969..15044	CDD:254352
Ig_3	15054..15132	CDD:316449
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	67	1.000	Domainoid score	I6485
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004229
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100287
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810