DRSC/TRiP Functional Genomics Resources

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Protein Alignment bt and Cntn3

DIOPT Version :9

Sequence 1:NP_001162825.1 Gene:bt / 43814 FlyBaseID:FBgn0005666 Length:8933 Species:Drosophila melanogaster
Sequence 2:NP_032805.2 Gene:Cntn3 / 18488 MGIID:99534 Length:1028 Species:Mus musculus


Alignment Length:1124 Identity:226/1124 - (20%)
Similarity:391/1124 - (34%) Gaps:326/1124 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 PSFVKKPQ-----LHQEDDGNRLIFECQLLSSPKPDIEWFRSDNKVVEDVRTKFKIQPVGENKYT 68
            |.|:|:|.     :..||  .::...|:...:|.|...|..:.:.:...:..::|:.  |.|   
Mouse    26 PVFIKEPSNSIFPVDSED--KKITLNCEARGNPSPHYRWQLNGSDIDTSLDHRYKLN--GGN--- 83

  Fly    69 VVLELDDVVETDAGLYKVKAKNKSGE-VSASINLNFTPADEPKEKQIDGFAPTFAKKPAIRQEED 132
             ::.::.....|.|.|:..|.|..|. ||....|.|.        .::.|........::|   :
Mouse    84 -LIVINPNRNWDTGSYQCFATNSLGTIVSREAKLQFA--------YLENFKTRMRSTVSVR---E 136

  Fly   133 GKRLLFECRVNADPIP-----AIIWFHN--GAAVKESERHKITVDKDVHSYFATLEILNVTVEDA 190
            |:.::..|    .|.|     :..|..|  .:.|:|..|..::.:.. |.|.|.:|     ..|.
Mouse   137 GQGVVLLC----GPPPHSGELSYAWVFNEYPSFVEEDSRRFVSQETG-HLYIAKVE-----PSDV 191

  Fly   191 GKYK--------------------VNAKNELGESNATISLNFDSDEAPVPESAEGIKPTFTERPV 235
            |.|.                    :.:...:||....|.:.|       ||:....|        
Mouse   192 GNYTCVVTSTVTNTRVLGSPTPLVLRSDGVMGEYEPKIEVQF-------PETLPAAK-------- 241

  Fly   236 IRQSEDGGNVTFECRCVGDPTPTVTW--SHGETELNESNRYKMSLTMDQKLYHIACLEISSVVSS 298
                  |..|..||..:|:|.|.:.|  |.|....|:....|.:          ..|||.:....
Mouse   242 ------GSTVRLECFALGNPVPQINWRRSDGMPFPNKIKLRKFN----------GMLEIQNFQQE 290

  Fly   299 DQGEYRAQAKNKHGSGVATINLNFESGSKKIPDGKSPRFPKKPTIRQ--------EEDLLIMECV 355
            |.|.|...|:|..|..||...|.:.:               ||...|        .||.|..||.
Mouse   291 DTGSYECIAENSRGKNVARGRLTYYA---------------KPYWLQLLRDVEIAVEDSLYWECR 340

  Fly   356 LEAHPVPDIVWYCSEKEICNNQRTKMTRKAITKDSYILTLEIQNPTKEDGGNYRCNAINMYGESN 420
            ....|.|...|..:...:...:|.::...|:|         |.|....|.|.::|.|.|.:|...
Mouse   341 ASGKPKPSYRWLKNGDALVLEERIQIENGALT---------ITNLNVTDSGMFQCIAENKHGLIY 396

  Fly   421 ANIALNFQGASDANGFAPSFIEKP--RIIPNESGTLITMKCKCKAKPEPTVTWYRGQDLVEKSKK 483
            ::..|....:      ||.|...|  :::..:.|:|:.:.||.:|.|.....|.:|..:|.:..:
Mouse   397 SSAELKVVAS------APDFSRNPMKKMVQVQVGSLVILDCKPRASPRALSFWKKGDMMVREQAR 455

  Fly   484 IK-INTTVIAEDTYELTLEIKDPGATDGGTYRCNVKNEYGESNANLNLNIEAEPEPEGEGPTFIE 547
            :. :|         :..|:|.:....|.|||.|..:|::|::|...:|.:..        ||.| 
Mouse   456 VSFLN---------DGGLKIMNVTKADAGTYTCTAENQFGKANGTTHLVVTE--------PTRI- 502

  Fly   548 KPRIVSENN-----GKLVIMECKVKADPKPDVI--WFRNGEVIKESNKIKTFIEQRGDQYYIKLE 605
               |::.:|     |:.||:.|:|:.||..|::  |:.|| .:.:..|..:..|:.|......|.
Mouse   503 ---ILAPSNMDVAVGESVILPCQVQHDPLLDIMFAWYFNG-ALTDFKKDGSHFEKVGGSSSGDLM 563

  Fly   606 LLDPQLEDSGLYKCNIKNTLGELNANLTLNIEIVPVIKDKPKIIKI------------IKKRTVV 658
            :.:.||:.||.|.|.::..:..:::...|.:...|...:..|:.:|            ....:.|
Mouse   564 IRNIQLKHSGKYVCMVQTGVDSVSSAAELIVRGSPGPPENVKVDEITDTTAQLSWTEGTDSHSPV 628

  Fly   659 IECTVASKFEPKCTWYKETSTVKE---SKRHVYQVEQTKEGEFAVKLEINDVEESDKGAYKLVAS 720
            |...|.:: .|....::...||.|   .|.|.           |..:|:|...|.:   :::|||
Mouse   629 ISYAVQAR-TPFSVGWQSVRTVPEVIDGKTHT-----------ATVVELNPWVEYE---FRIVAS 678

  Fly   721 NEKG--------------EAVSQIV------------NLV----DIPEEER-----------KP- 743
            |:.|              ||..:|.            .||    .:|||.:           :| 
Mouse   679 NKIGGGEPSLPSEKVRTEEAAPEIAPSEVSGGGGSRSELVITWDPVPEELQNGGGFGYVVAFRPL 743

  Fly   744 ----------CKPEISRKLADQKVAESKTFELLVSLSQTDRKCKVEWYKGS------TVIRETKD 792
                      ..|:..|.:...        |.:|..|..:.|..|...||.      |.:...::
Mouse   744 GVTTWIQTVVTSPDNPRYVFRN--------ESIVPFSPYEVKVGVYNNKGEGPFSPVTTVFSAEE 800

  Fly   793 ITTTFDGTTARLTFSSARTE-------------HTSNYKVIVTNEVGKDESSCKI---------- 834
            ..|......:..:.||:..|             |...|:|...|..|::|||.|:          
Mouse   801 EPTVAPSHISAHSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNNGGEEESSRKVKVAGNQTSAV 865

  Fly   835 ---------------------------TVEKVAKK--KEEKPKEKEKTKNEKEV----EQ-KEME 865
                                       ||....||  ..:.|........:.:|    || |.||
Mouse   866 LRGLKSNLAYYTAVRAYNSAGAGPFSATVNATTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAME 930

  Fly   866 EDKNESGQSV-AQTEGRINIEQISEGDPKEE--LTVKEEILDKRDTQEVKESSVELQDSAGHEVP 927
            .:...:|..| .:|..:.|:..::......|  |.:||:.:     .|||.::.....::..::.
Mouse   931 NESEVTGYKVFYRTSSQNNVHVLNTNKTSAELLLPIKEDYI-----IEVKATTDGGDGTSSEQIR 990

  Fly   928 EPKKATSDSKLDQSNQKNL 946
            .|:..:.|::...|...|:
Mouse   991 IPRITSMDARGSTSAISNI 1009

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
btNP_001162825.1 I-set 9..101 CDD:254352 21/97 (22%)
Ig 26..100 CDD:143165 15/74 (20%)
I-set 119..210 CDD:254352 20/117 (17%)
Ig 136..209 CDD:143165 17/99 (17%)
I-set 228..320 CDD:254352 23/93 (25%)
IGc2 242..312 CDD:197706 20/71 (28%)
I-set 335..425 CDD:254352 22/97 (23%)
Ig 350..423 CDD:143165 17/72 (24%)
Ig 436..530 CDD:299845 24/96 (25%)
I-set 438..532 CDD:254352 24/96 (25%)
I-set 545..636 CDD:254352 25/97 (26%)
Ig 560..633 CDD:143165 20/74 (27%)
Ig 657..731 CDD:143165 20/90 (22%)
I-set 746..835 CDD:254352 23/144 (16%)
Ig 1496..1586 CDD:299845
IG_like 1503..1588 CDD:214653
I-set 1639..1724 CDD:254352
IG 1750..1821 CDD:214652
IGc2 1750..1806 CDD:197706
I-set 1826..1909 CDD:254352
Ig 1831..1897 CDD:299845
I-set 1914..1998 CDD:254352
Ig 2020..2095 CDD:299845
FN3 2100..2194 CDD:238020
FN3 2203..2292 CDD:238020
I-set 2311..2395 CDD:254352
Ig 2321..2395 CDD:299845
FN3 2399..2493 CDD:238020
FN3 2501..2590 CDD:238020
I-set 2602..2693 CDD:254352
Ig 2619..2693 CDD:299845
FN3 2697..2793 CDD:238020
FN3 2801..2893 CDD:238020
I-set 2902..2995 CDD:254352
Ig 2919..2993 CDD:299845
FN3 2999..3088 CDD:238020
FN3 3102..3191 CDD:238020
I-set 3208..3292 CDD:254352
Ig 3219..3292 CDD:299845
FN3 3296..3390 CDD:238020
FN3 3400..3489 CDD:238020
I-set 3494..3590 CDD:254352
Ig 3516..3590 CDD:299845
FN3 3594..3682 CDD:238020
FN3 3694..3781 CDD:238020
I-set 3795..3885 CDD:254352
Ig 3813..3885 CDD:299845
FN3 3889..3980 CDD:238020
FN3 3990..4082 CDD:238020
I-set 4090..4181 CDD:254352
Ig 4108..4181 CDD:299845
FN3 4185..4271 CDD:238020
FN3 4285..4383 CDD:238020
Ig 4404..4480 CDD:299845
FN3 4484..4571 CDD:238020
FN3 4584..4677 CDD:238020
I-set 4685..4775 CDD:254352
Ig 4703..4775 CDD:299845
FN3 4779..4863 CDD:238020
FN3 4879..4970 CDD:238020
IG 4989..5069 CDD:214652
Ig 4996..5069 CDD:299845
FN3 5073..5166 CDD:238020
FN3 5175..5265 CDD:238020
I-set 5276..5366 CDD:254352
Ig 5293..5366 CDD:299845
FN3 5370..5462 CDD:238020
FN3 5470..5561 CDD:238020
Ig 5559..5654 CDD:299845
I-set 5570..5660 CDD:254352
FN3 5664..5755 CDD:238020
FN3 5764..5853 CDD:238020
I-set 5865..5954 CDD:254352
Ig 5882..5954 CDD:299845
FN3 5958..6049 CDD:238020
FN3 6062..6153 CDD:238020
I-set 6173..6255 CDD:254352
Ig_Titin_like 6182..6255 CDD:143225
FN3 6259..6350 CDD:238020
FN3 6359..6451 CDD:238020
FN3 6470..6552 CDD:238020
I-set 6564..6650 CDD:254352
Ig_Titin_like 6577..6650 CDD:143225
FN3 6654..6745 CDD:238020
FN3 6754..6840 CDD:238020
I-set 6855..6946 CDD:254352
Ig 6874..6946 CDD:299845
FN3 6950..7042 CDD:238020
FN3 7050..7139 CDD:238020
FN3 7151..7237 CDD:238020
I-set 7254..7334 CDD:254352
Ig 7272..7339 CDD:143165
IG_like 7354..7440 CDD:214653
Ig 7366..7440 CDD:299845
FN3 7444..7531 CDD:238020
FN3 7545..7637 CDD:238020
I-set 7648..7737 CDD:254352
Ig 7665..7734 CDD:143165
Ig 7760..7833 CDD:299845
FN3 7837..7927 CDD:238020
STKc_Twitchin_like 7986..8244 CDD:271016
S_TKc 7989..8244 CDD:214567
Ig 8311..8394 CDD:299845
I-set 8312..8401 CDD:254352
I-set 8437..8525 CDD:254352
Ig 8455..8519 CDD:143165
I-set 8632..8721 CDD:254352
IGc2 8646..8711 CDD:197706
I-set 8740..8831 CDD:254352
Ig 8757..8826 CDD:143165
I-set 8839..8922 CDD:254352
Ig 8845..>8909 CDD:299845
Cntn3NP_032805.2 Ig 25..120 CDD:416386 23/109 (21%)
Ig strand A 27..31 CDD:409353 1/3 (33%)
Ig strand A' 34..39 CDD:409353 0/4 (0%)
Ig strand B 45..53 CDD:409353 1/7 (14%)
Ig strand C 58..64 CDD:409353 2/5 (40%)
Ig strand C' 66..69 CDD:409353 0/2 (0%)
Ig strand D 76..80 CDD:409353 1/3 (33%)
Ig strand E 82..88 CDD:409353 1/9 (11%)
Ig strand F 95..104 CDD:409353 3/8 (38%)
Ig strand G 107..120 CDD:409353 5/20 (25%)
Ig 129..214 CDD:416386 17/97 (18%)
Ig strand A 130..135 CDD:409353 0/4 (0%)
Ig strand B 139..145 CDD:409353 1/9 (11%)
Ig strand C 153..159 CDD:409353 1/5 (20%)
Ig strand C' 164..166 CDD:409353 0/1 (0%)
Ig strand D 171..176 CDD:409353 1/4 (25%)
Ig strand E 179..183 CDD:409353 1/4 (25%)
Ig strand F 193..201 CDD:409353 1/7 (14%)
Ig strand G 203..214 CDD:409353 0/10 (0%)
Ig 227..315 CDD:416386 29/118 (25%)
Ig strand A 227..232 CDD:409353 1/4 (25%)
Ig strand A' 235..240 CDD:409353 1/4 (25%)
Ig strand B 243..252 CDD:409353 3/8 (38%)
Ig strand C 258..262 CDD:409353 0/3 (0%)
Ig strand C' 265..267 CDD:409353 0/1 (0%)
Ig strand D 276..279 CDD:409353 1/2 (50%)
Ig strand E 280..285 CDD:409353 2/4 (50%)
Ig strand F 293..301 CDD:409353 3/7 (43%)
Ig strand G 304..315 CDD:409353 4/10 (40%)
Ig 320..403 CDD:416386 21/91 (23%)
Ig strand A' 326..330 CDD:409353 0/3 (0%)
Ig strand B 334..342 CDD:409353 3/7 (43%)
Ig strand C 348..353 CDD:409353 1/4 (25%)
Ig strand C' 355..358 CDD:409353 0/2 (0%)
Ig strand D 363..367 CDD:409353 1/3 (33%)
Ig strand E 369..374 CDD:409353 2/13 (15%)
Ig strand F 383..390 CDD:409353 2/6 (33%)
Ig strand G 394..403 CDD:409353 1/8 (13%)
Ig 408..496 CDD:416386 24/96 (25%)
Ig strand A 408..413 CDD:409353 2/4 (50%)
Ig strand A' 416..421 CDD:409353 0/4 (0%)
Ig strand B 425..432 CDD:409353 1/6 (17%)
Ig strand C 440..444 CDD:409353 0/3 (0%)
Ig strand D 458..461 CDD:409353 1/11 (9%)
Ig strand E 462..467 CDD:409353 1/4 (25%)
Ig strand F 475..483 CDD:409353 4/7 (57%)
Ig strand G 489..496 CDD:409353 2/6 (33%)
Ig 498..598 CDD:416386 27/112 (24%)
Ig strand A 498..504 CDD:409353 3/17 (18%)
Ig strand A' 507..512 CDD:409353 1/4 (25%)
Ig strand B 515..523 CDD:409353 3/7 (43%)
Ig strand C 532..536 CDD:409353 0/3 (0%)
Ig strand E 560..564 CDD:409353 1/3 (33%)
Ig strand F 573..580 CDD:409353 3/6 (50%)
Ig strand G 587..591 CDD:409353 0/3 (0%)
FN3 598..695 CDD:238020 21/111 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 684..714 3/29 (10%)
FN3 703..795 CDD:238020 16/99 (16%)
FN3 805..898 CDD:238020 14/92 (15%)
FN3 906..991 CDD:238020 18/89 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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