DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ey and YHP1

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_010739.3	Gene:	YHP1 / 852062	SGDID:	S000002859	Length:	353	Species:	Saccharomyces cerevisiae

Alignment Length:	322	Identity:	57/322 - (17%)
Similarity:	111/322 - (34%)	Gaps:	86/322 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   372 TSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQ 436
            ||::  |:|....::|.:.:.....:.....||..:.|.             :.:::...|...:
Yeast    86 TSMT--PLSKPKKLSSHSPFTPTVRVCSKEQPPQSMHSY-------------KKVNILTPLSAAK 135

  Fly   437 SDETGSGEGENSNGGASNIGNTED--------DQARLILKRKLQRNRTSFTNDQIDSLEKEFERT 493
            :..|.:...|.....|....:.|.        |.||| .:||  |.|||  :.::..|:..|:..
Yeast   136 AVLTPTTRKEKKRSFAFITHSQETFPKKEPKIDNARL-ARRK--RRRTS--SYELGILQTAFDEC 195

  Fly   494 HYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRTPNSTGASATSSSTSATASLT 558
            ..|:...|..|:.:..:.|..:|:||.|:|      :..:..:.:.|::.....|:.:.:..|.:
Yeast   196 PTPNKAKRIELSEQCNMSEKSVQIWFQNKR------QAAKKHKNSGNTSHCKVHSNDSMSMISYS 254

  Fly   559 DSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGAGIDSSESPTPIPHIRPSCTS 623
            |:...::                     |:|::....:.|..|.....::.|.....||.|
Yeast   255 DAALEIT---------------------STPTSTKEAITAELLKTSPANTSSIFEDHHITP---- 294

  Fly   624 DNDNGRQSEDCRRVCSPCPLGVGGHQNTHH--------IQSNGHAQGHALVPAISPRLNFNS 677
                          |.|     ||....|.        :.:.||::..........||.||:
Yeast   295 --------------CKP-----GGQLKFHRKSVLVKRTLSNTGHSEIIKSPKGKENRLKFNA 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	14/51 (27%)
YHP1	NP_010739.3	COG5576	123..278	CDD:227863	34/186 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030