DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ey and ATHB-15

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_849795.1	Gene:	ATHB-15 / 841645	AraportID:	AT1G52150	Length:	837	Species:	Arabidopsis thaliana

Alignment Length:	765	Identity:	137/765 - (17%)
Similarity:	244/765 - (31%)	Gaps:	287/765 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 PSPTMEAVEASTASHPHSTSSYFATTYYHLTDDECHSGVNQLGGVFVGGRPLPDSTRQKIVELAH 127
            |:|::.|.:.|..|         ..|          ||.:||    ....|..|::...::.:|.
plant   122 PNPSLPAKDTSCES---------VVT----------SGQHQL----ASQNPQRDASPAGLLSIAE 163

  Fly   128 S--------------------GARP-CDISRILQVSNGCVSKILGRYYETGSIRPRAIG--GSKP 169
            .                    |.:| .|...|:.:|:||          || :..||.|  |.:|
plant   164 ETLAEFLSKATGTAVEWVQMPGMKPGPDSIGIIAISHGC----------TG-VAARACGLVGLEP 217

  Fly   170 RVATAEVVSKISQYKRECPSIFAWEIRDRLLQENVCTNDNI------PSVSSINR---------V 219
             ...||:|.....:.|||.::   |:.:.|...|..|.:.:      |:..:..|         |
plant   218 -TRVAEIVKDRPSWFRECRAV---EVMNVLPTANGGTVELLYMQLYAPTTLAPPRDFWLLRYTSV 278

  Fly   220 LRN---LAAQKEQQSTGSGSSSTSAGNSISAKVSVS--------IGGNVSNVAS----------- 262
            |.:   :..::..:||.:|.|.....|.:.|::..|        .||::.::..
plant   279 LEDGSLVVCERSLKSTQNGPSMPLVQNFVRAEMLSSGYLIRPCDGGGSIIHIVDHMDLEACSVPE 343

  Fly   263 ------------GSRGTLSSSTDLMQTA---TPLNSSESG------------------------- 287
                        ..:.|:::...|.|.|   |..|||.:|
plant   344 VLRPLYESPKVLAQKTTMAALRQLKQIAQEVTQTNSSVNGWGRRPAALRALSQRLSRGFNEAVNG 408

  Fly   288 ----GASNSGEGSEQEAIY-----EKLRLLNTQHAAGPGPLEP----ARAAPLVGQSPNHLGTRS 339
                |.|..|:..:...|.     :||..||...|.|..|:..    |:|:.|:...|..:..|
plant   409 FTDEGWSVIGDSMDDVTITVNSSPDKLMGLNLTFANGFAPVSNVVLCAKASMLLQNVPPAILLR- 472

  Fly   340 SHPQLVHGNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASG-------PSL 397
                       .|::|:.:          |...:: :..:::|..:...:|...|       | |
plant   473 -----------FLREHRSE----------WADNNI-DAYLAAAVKVGPCSARVGGFGGQVILP-L 514

  Fly   398 AHSLSPPNDIE--SLASIGHQRNCPVATEDIHLKKELDGHQSDETG------------------- 441
            ||::.....:|  .|..:||.....:...||.|.:...|...:..|
plant   515 AHTIEHEEFMEVIKLEGLGHSPEDAIVPRDIFLLQLCSGMDENAVGTCAELIFAPIDASFADDAP 579

  Fly   442 ------------SGEGENSN-------GGASNIGN----TEDDQ------ARLILKRKLQRNRTS 477
                        |.:.|.|:       ..|..||:    ...||      ||.::....:....|
plant   580 LLPSGFRIIPLDSAKQEVSSPNRTLDLASALEIGSAGTKASTDQSGNSTCARSVMTIAFEFGIES 644

  Fly   478 FTNDQIDSLEKEFERTHYPDV------FARERLAGKIGL------PEAR-IQVWFSNRRAKWRRE 529
            ...:.:.|:.:::.|.....|      .:...::.::||      |||: :..|.......:...
plant   645 HMQEHVASMARQYVRGIISSVQRVALALSPSHISSQVGLRTPLGTPEAQTLARWICQSYRGYMGV 709

  Fly   530 EKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLST 594
            |.|::     ||.|      :.|...:|....:::..||                  .....:.|
plant   710 ELLKS-----NSDG------NESILKNLWHHTDAIICCS------------------MKALPVFT 745

  Fly   595 NVNAPTLGAGIDSSESPTPIPHIRPSCTSD--NDNGRQSEDCRRVCSPCP 642
            ..|.    ||:|..|  |.:..::......  :||||::     :||..|
plant   746 FANQ----AGLDMLE--TTLVALQDISLEKIFDDNGRKT-----LCSEFP 784

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	34/160 (21%)
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	10/64 (16%)
ATHB-15	NP_849795.1	Homeobox	17..74	CDD:278475
		bZIP	<69..108	CDD:269834
		START_ArGLABRA2_like	155..371	CDD:176884	41/230 (18%)
		MEKHLA	693..832	CDD:285833	24/132 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910