DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ey and lhx2a

DIOPT Version :9

Sequence 1:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_017208320.1	Gene:	lhx2a / 795283	ZFINID:	ZDB-GENE-091118-109	Length:	328	Species:	Danio rerio

Alignment Length:	200	Identity:	56/200 - (28%)
Similarity:	83/200 - (41%)	Gaps:	40/200 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   427 HLKKE--LDGHQSD----ETGSG---------------EGENSNGGASNIGNTED------DQAR 464
            |:::|  .|.:.||    ||.|.               ....:|..|.:|..:.|      |.:.
Zfish   129 HIQRECHADLYYSDMSSRETNSESHTYDEESPVHRARVRRRKNNSTADHIAYSSDVSDLGVDLSE 193

  Fly   465 LILKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRRE 529
            .:..:|.:|.||||.:.|:.|::..|...|.||....:.||.|.||.:..:||||.|.|||:||.
Zfish   194 RVSCQKSKRMRTSFKHHQLRSMQSFFTHNHNPDAKDLKELAQKTGLTKRVLQVWFQNARAKFRRN 258

  Fly   530 EKLRNQRRTPNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLST 594
            ...:      .|.|....|.:::.|:....||.......|..|.|...||..|      ||. :.
Zfish   259 CLYQ------ESIGVDNVSDNSTLTSPSVPSPELCHGSMSPSSPSGTSPSQHT------PSA-AR 310

  Fly   595 NVNAP 599
            |.::|
Zfish   311 NTHSP 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	23/51 (45%)
lhx2a	XP_017208320.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910