Protein Alignment ey and Nkx1-1

DIOPT Version :9

• Sequence 1: NP_001014693.1
• Gene: ey / 43812
• FlyBaseID: FBgn0005558
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_035450.1
• Gene: Nkx1-1 / 672284
• MGIID: 109346
• Length: 440
• Species: Mus musculus
• Alignment Length: 601
• Identity: 127/601 - (21%)
• Similarity: 189/601 - (31%)
• Gaps: 228/601 - (37%)

  Fly    48 LGTAGGSGLGGIAGKPSPTMEAVEASTASHPHSTSSYFATTYYHLTDDECHSGVNQLGGVFVGGR 112
            :.|:|.:..|.:...|.|............|.:|:.                      ....|..
Mouse     1 MSTSGPAAPGDVPALPPPPPGPGSGPAPPAPAATAR----------------------DTMDGRA 43

  Fly   113 PLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATAEVV 177
            .||...|..:..||.|...|.       |..|           .|:.||.|    .||..:..|:
Mouse    44 ELPIFPRAGVPPLAASDTVPA-------VPEG-----------AGAARPAA----PPRPTSFSVL 86

  Fly   178 -----SKISQYKREC-------PSIFAWEIRDRLLQENVCTNDNIPSVSSINRVLRNLAAQKEQQ 230
                 :|.:..:|.|       |:..|      ......|.  .:|:.|.     |:..|:.|::
Mouse    87 DILDPNKFNSRRRRCVLLGPVVPATCA------PCAPAACV--AVPAASG-----RSPRAELERR 138

  Fly   231 ----STG----SGSSSTSAGNSISAKVSVSIGGNVSNVASGSRGTLSSSTDLMQTATPLNSSESG 287
                :||    :|:..||||:|..|                                  :.:|:.
Mouse   139 ALSAATGVAAAAGAEPTSAGDSYRA----------------------------------DEAEAN 169

  Fly   288 GASNSGEG------SEQEAIYEKLRLLNTQHAAGPGPLEPARAAPLVGQSPNHLGTRSSHPQLVH 346
            |.| ||.|      ||.||..:                |....||.|
Mouse   170 GYS-SGSGRSPTADSEDEAPED----------------EDEEEAPEV------------------ 199

  Fly   347 GNHQALQQHQQQSWPPRHYSGSWYPTSLSEIPISSAPNIASVTAYASGPSLAHSLSPPNDIESLA 411
                   |..|.:..||..||......      |..|..|.|.|           ||   ::..|
Mouse   200 -------QDAQGTEEPRGGSGGLGARG------SGCPGAAEVEA-----------SP---VDDTA 237

  Fly   412 SIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGNTEDDQARL---ILKRKLQR 473
            :.|.:.|.|.|          .|..:..||:|...::..||:  ..|:..:.|.   ....|.:|
Mouse   238 APGPRGNSPGA----------PGPPATATGAGSAGSTPQGAA--VTTKPKRKRTGSDSKSGKPRR 290

  Fly   474 NRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEKLRNQRRT 538
            .||:||.:|:.:||.:|:.|.|..|..|..||..:.|.|.::::||.|||.||:::
Mouse   291 ARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQ--------- 346

  Fly   539 PNSTGASATSSSTSATASLTDSPNSLSACSSLLSGSAGGPSVSTINGLSSPSTLSTNVNAPTLGA 603
              :.||.            |.:|          :|..|||......|...|..||....:|.:||
Mouse   347 --NPGAD------------TSAP----------TGGGGGPGPGAGPGAGLPGGLSPLSPSPPMGA 387

  Fly   604 GIDSSESPTPIPHIRP 619
            .: :...|...|...|
Mouse   388 PL-ALHGPAGYPAHSP 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ey	NP_001014693.1	PAX	98..221	CDD:128645	25/134 (19%)
		Homeobox	475..527	CDD:278475	22/51 (43%)
Nkx1-1	NP_035450.1	Homeobox	292..344	CDD:278475	22/51 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910